Differential effects of IL-1ra on sickness behavior and weight loss induced by IL-1 in rats

Interleukin-1 and interleukin-1 antagonism

1991 • 2,276 citations

Biology of interleukin 1

1988 • 1,547 citations

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

1990 • 1,143 citations

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

1990 • 1,095 citations

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 • 972 citations

Interleukin-1 receptor antagonist reduces mortality from endotoxin shock

1990 • 865 citations

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1991 • 729 citations

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

1991 • 677 citations

Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein

1990 • 609 citations

Interleukin 1 receptor antagonist. A new member of the interleukin 1 family.

1991 • 589 citations

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

1994 • 502 citations

Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction

1991 • 457 citations

In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse

1992 • 335 citations

Interleukin-1-induced anorexia in the rat. Influence of prostaglandins.

1989 • 333 citations

Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1.

1992 • 319 citations

Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody.

1991 • 295 citations

Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism.

1994 • 276 citations

Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor

1991 • 262 citations

Interleukin 1 alters rat sleep: temporal and dose-related effects

1991 • 223 citations

Interleukin 1 receptor blockade attenuates the host inflammatory response.

1990 • 216 citations

Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s).

1986 • 211 citations

Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes

1992 • 155 citations

Interleukin 1-receptor antagonist blocks interleukin 1-induced sleep and fever

1991 • 149 citations

Expression of type I and type II interleukin-1 receptors in mouse brain

1994 • 147 citations

Interleukin-1 receptor antagonist binds to the type II interleukin-1 receptor on B cells and neutrophils.

1991 • 106 citations

Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment

1990 • 102 citations

Intracerebroventricular administration of a specific IL-1 receptor antagonist blocks food and water intake suppression induced by interleukin-1β

1992 • 94 citations

Androgen-dependent vasopressinergic neurotransmission attenuates interleukin-1-induced sickness behavior

1991 • 85 citations

Behavioral Effects of Cytokines: An Insight into Mechanisms of Sickness Behavior

1993 • 83 citations

Somnogenic cytokines and models concerning their effects on sleep.

1990 • 72 citations

Sex differences in corpus callosum: Influence of prenatal alcohol exposure and maternal undernutrition

1990 • 60 citations

Interleukin-1 inhibitors

1987 • 49 citations

Molecular Identification of Two Types of lnterleukin‐1 Receptors in the Murine Pituitary Gland

1993 • 47 citations

Roles of interleukin-1 and tumor necrosis factor in lipopolysaccharide-induced hypoglycemia

1991 • 45 citations

Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat

1993 • 45 citations

Neurobiology of Cytokines

1993 • 44 citations

CRF is not involved in the behavioral effects of peripherally injected interleukin 1 in the rat

1989 • 42 citations

Interleukin 1 alpha and an interleukin 1 beta fragment are somnogenic

1990 • 39 citations

Aphagic and adipsic effects of interleukin-1

1991 • 37 citations

Interleukin-1 receptor antagonist blocks effects of IL-1α and IL-1β on social behaviour and body weight in mice

1991 • 35 citations

Inhibition by interleukin 1 receptor antagonist of in vivo activities of interleukin 1 in mice.

1991 • 18 citations

CRF is not involved in the behavioural effects of peripherally injected interleukin 1 in the rat

1989 • 17 citations

[Study of the effect of phenophtorazole on the calcium ion concentration in rat thymocyte cytoplasm and on changes of this parameter, induced by concanavalin A].

1991 • 16 citations

Monoclonal antibody 1994-01 (also known as ALVA 42) reported to recognize type II IL-1 receptor is specific for HLA-DR alpha and beta chains

1994 • 15 citations

Biological role of the IL-1 receptor type II (IL-1RII) as defined by a monoclonal antibody

1991 • 11 citations

Deleted Work

1955 • 0 citations