MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

1979 • 7,240 citations

Numerical Analysis

1978 • 7,025 citations

Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance

1979 • 4,730 citations

Quantitative estimation of insulin sensitivity.

1979 • 1,822 citations

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose.

1981 • 1,606 citations

Assessment of Insulin Sensitivityin Vivo*

1985 • 1,076 citations

Mechanisms of Insulin Resistance in Aging

1983 • 543 citations

Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes

1970 • 500 citations

Pathogenesis of Age-Related Glucose Intolerance in Man: Insulin Resistance and Decreased β-Cell Function*

1985 • 350 citations

Multiexponential, multicompartmental, and noncompartmental modeling. II. Data analysis and statistical considerations

1984 • 345 citations

The mathematical modeling of metabolic and endocrine systems

1984 • 336 citations

Quantitative Estimation of Beta Cell Sensitivity to Glucose in the Intact Organism: A Minimal Model of Insulin Kinetics in the Dog

1980 • 278 citations

Decreased Sensitivity of the Pancreatic Beta Cells to Glucose in Prediabetic and Diabetic Subjects: A Glucose Dose-Response Study

1972 • 252 citations

A modified Marquardt subroutine for non-linear least squares

1971 • 180 citations

Importance of Glucose Per Se to Intravenous Glucose Tolerance: Comparison of the Minimal-Model Prediction with Direct Measurements

1985 • 166 citations

Potentiation of Insulin Secretory Responses by Plasma Glucose Levels in Man: Evidence That Hyperglycemia in Diabetes Compensates for Impaired Glucose Potentiation*

1979 • 151 citations

Insulin-independent diabetes mellitus: Metabolic characteristics

1980 • 107 citations

Minimal modeling, partition analysis, and the estimation of insulin sensitivity.

1980 • 94 citations

Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog

1980 • 90 citations

The Insulin Sensitivity Index: Correlation in Dogs Between Values Determined from the Intravenous Glucose Tolerance Test and the Euglycemic Glucose Clamp

1984 • 88 citations

A Simplified Method Using Somatostatin to Assess In Vivo Insulin Resistance over a Range of Obesity

1979 • 59 citations

Importance of glucose per se to intravenous glucose tolerance. Comparison of the minimal-model prediction with direct measurements

1985 • 52 citations

Optimal Design of Multioutput Sampling Schedules - Software and Applications to Endocrine - Metabolic and Pharmacokinetic Models

1985 • 52 citations

A Minimal-Model-Based Glucose Clamp Yielding Insulin Sensitivity Independent of Glycemia

1982 • 42 citations

PACBERG: An adaptive program for controlling the blood sugar

1983 • 33 citations

The insulin sensitivity index. Correlation in dogs between values determined from the intravenous glucose tolerance test and the euglycemic glucose clamp

1984 • 29 citations

A minimal-model-based glucose clamp yielding insulin sensitivity independent of glycemia

1982 • 16 citations

A simplified method using somatostatin to assess in vivo insulin resistance over a range of obesity

1979 • 15 citations