Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor induction by the carcinogen N-hydroxy-N-2-fluorenylacetamide
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References (42)
Immunology of Experimental Tumors
1964 • 487 citations
N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat.
1961 • 336 citations
IMMUNITY AND CYSTIC FIBROSIS.
1965 • 300 citations
FACTORS DETERMINING SHORT- AND LONG-TERM SURVIVAL AFTER ORTHOTOPIC LIVER HOMOTRANSPLANTATION IN THE DOG.
1965 • 180 citations
Human Transplantation
1968 • 170 citations
Immunologic Rejection of Human Cancer Transplanted with a Renal Allograft
1968 • 168 citations
Molecular Geometry and Carcinogenic Activity of Aromatic Compounds. New Perspectives
1969 • 137 citations
The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent.
1955 • 135 citations
Development of Preneoplastic and Neoplastic Lesions of the Liver in Male Rats Given 0.025 Percent <italic>N</italic>-2-Fluorenyldiacetamide<xref ref-type="fn" rid="FN2">2</xref>
1965 • 128 citations
Survey of Compounds Which Have Been Tested for Carcinogenic Activity
1953 • 120 citations
EIGHTH REPORT OF THE HUMAN KIDNEY TRANSPLANT REGISTRY
1971 • 111 citations
Cadaveric Renal Homotransplantation With Inadvertent Transplantation of Carcinoma
1965 • 109 citations
Tests for chemical carcinogens. Report on the activity of derivatives of aromatic amines, nitrosamines, quinolines, nitroalkanes, amides, epoxides, aziridines, and purine antimetabolites.
1968 • 103 citations
Metabolic Basis for the Actions of Analogs of Purines and Pyrimidines
1965 • 96 citations
Antigenic Structure of Chemically-Induced Hepatomas
2015 • 80 citations
TREATMENT OF ACTIVE CHRONIC HEPATITIS AND LUPOID HEPATITIS WITH 6-MERCAPTOPURINE AND AZOTHIOPRINE
1964 • 79 citations
THE TREATMENT OF ACTIVE CHRONIC HEPATITIS WITH 6‐MERCAPTOPURINE AND AZATHIOPRINE
1967 • 77 citations
Influence of Adrenocortical, Androgenic, and Anabolic Hormones on the Development of Carcinoma and Cirrhosis of the Liver in A × C Rats Fed <italic>N</italic>-2-Fluorenyldiacetamide<xref ref-type="fn" rid="FN1">2</xref>
1961 • 77 citations
CHRONIC HEPATITIS: EFFECT OF PROLONGED SUPPRESSIVE TREATMENT AND COMPARISON OF AZATHIOPRINE WITH PREDNISOLONE
1968 • 74 citations
Hepatotoxicity of mercaptopurine
1968 • 68 citations
Evidence for Cancer-specific Antigens in Man
2015 • 64 citations
Immunotherapy of Cancer: Experiments with Primary Tumours and Syngeneic Tumour Grafts
2015 • 59 citations
Survey of Compounds Which Have Been Tested for Carcinogenic Activity
1971 • 56 citations
Treatment of refractory idiopathic thrombocytopenic purpura.
1969 • 56 citations
Factors determining short and long-term survival after orthotopic liver homotransplantation in the dog
1966 • 51 citations
Brief Report: The Development of Lymphomas in Mice with Autoimmune Disorders Treated with Azathioprine
1968 • 49 citations
Homotransplantation of a Cadaver Neoplasm and a Renal Homograft
1965 • 47 citations
Tumor-specific antigens of putatively nonviral tumors.
1968 • 45 citations
FIFTH REPORT OF THE HUMAN KIDNEY TRANSPLANT REGISTRY
1967 • 43 citations
Hyperglycemic, Hyperosmolar, Nonketoacidotic Diabetes: A Complication of Steroid and Immunosuppressive Therapy
1969 • 35 citations
THE EFFECT OF DIETARY COPPER ON RAT CARCINOGENESIS BY 3-METHOXY DYES. I. TUMORS INDUCED AT VARIOUS SITES BY FEEDING 3-METHOXY-4-AMINOAZOBENZENE AND ITS N-METHYL DERIVATIVE.
1964 • 33 citations
Progress in clinical renal homotransplantation.
1966 • 28 citations
Effects of pituitary hormones and prefeeding N-hydroxy-N-2-fluorenylacetamide on the metabolism of this carcinogen and on physiologic parameters.
1966 • 24 citations
RENAL TRANSPLANTATION FROM CADAVER DONORS
1968 • 23 citations
“Auto-immune” Chronic Hepatitis
1967 • 20 citations
Endocrine factors as determinants of the susceptibility of the liver to carcinogenic agents.
1968 • 19 citations
The metabolism of N-2-fluorenylhydroxyl-amine in male and female rats
1966 • 17 citations
Development of leukemia in rats by oral administration of N-nitrosobutylurea in the drinking water.
1969 • 14 citations
Immunity, Cancer, and Chemotherapy: Basic Relationships in the Cellular Level
1968 • 9 citations
The Effect of Immunosuppressive Drugs on Cellular Changes after Antigenic Stimulation
1967 • 8 citations
Treatment of refractory idiopathic thrombocytopenic purpura
1969 • 7 citations
Beeinflussung der Überlebenszeit von Hauthomotransplantaten bei Ratten durch Azathioprin
1969 • 2 citations