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Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor induction by the carcinogen N-hydroxy-N-2-fluorenylacetamide

Data up to Jan 2025

Published1970
Citations23
References42

Total Citations Per Year

Abstract

References (42)

Immunology of Experimental Tumors

1964 • 487 citations

N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat.

1961 • 336 citations

IMMUNITY AND CYSTIC FIBROSIS.

1965 • 300 citations

FACTORS DETERMINING SHORT- AND LONG-TERM SURVIVAL AFTER ORTHOTOPIC LIVER HOMOTRANSPLANTATION IN THE DOG.

1965 • 180 citations

Human Transplantation

1968 • 170 citations

Immunologic Rejection of Human Cancer Transplanted with a Renal Allograft

1968 • 168 citations

Molecular Geometry and Carcinogenic Activity of Aromatic Compounds. New Perspectives

1969 • 137 citations

The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent.

1955 • 135 citations

Development of Preneoplastic and Neoplastic Lesions of the Liver in Male Rats Given 0.025 Percent <italic>N</italic>-2-Fluorenyldiacetamide<xref ref-type="fn" rid="FN2">2</xref>

1965 • 128 citations

Survey of Compounds Which Have Been Tested for Carcinogenic Activity

1953 • 120 citations

EIGHTH REPORT OF THE HUMAN KIDNEY TRANSPLANT REGISTRY

1971 • 111 citations

Cadaveric Renal Homotransplantation With Inadvertent Transplantation of Carcinoma

1965 • 109 citations

Tests for chemical carcinogens. Report on the activity of derivatives of aromatic amines, nitrosamines, quinolines, nitroalkanes, amides, epoxides, aziridines, and purine antimetabolites.

1968 • 103 citations

Metabolic Basis for the Actions of Analogs of Purines and Pyrimidines

1965 • 96 citations

Antigenic Structure of Chemically-Induced Hepatomas

2015 • 80 citations

TREATMENT OF ACTIVE CHRONIC HEPATITIS AND LUPOID HEPATITIS WITH 6-MERCAPTOPURINE AND AZOTHIOPRINE

1964 • 79 citations

THE TREATMENT OF ACTIVE CHRONIC HEPATITIS WITH 6‐MERCAPTOPURINE AND AZATHIOPRINE

1967 • 77 citations

Influence of Adrenocortical, Androgenic, and Anabolic Hormones on the Development of Carcinoma and Cirrhosis of the Liver in A × C Rats Fed <italic>N</italic>-2-Fluorenyldiacetamide<xref ref-type="fn" rid="FN1">2</xref>

1961 • 77 citations

CHRONIC HEPATITIS: EFFECT OF PROLONGED SUPPRESSIVE TREATMENT AND COMPARISON OF AZATHIOPRINE WITH PREDNISOLONE

1968 • 74 citations

Hepatotoxicity of mercaptopurine

1968 • 68 citations

Evidence for Cancer-specific Antigens in Man

2015 • 64 citations

Immunotherapy of Cancer: Experiments with Primary Tumours and Syngeneic Tumour Grafts

2015 • 59 citations

Survey of Compounds Which Have Been Tested for Carcinogenic Activity

1971 • 56 citations

Treatment of refractory idiopathic thrombocytopenic purpura.

1969 • 56 citations

Factors determining short and long-term survival after orthotopic liver homotransplantation in the dog

1966 • 51 citations

Brief Report: The Development of Lymphomas in Mice with Autoimmune Disorders Treated with Azathioprine

1968 • 49 citations

Homotransplantation of a Cadaver Neoplasm and a Renal Homograft

1965 • 47 citations

Tumor-specific antigens of putatively nonviral tumors.

1968 • 45 citations

FIFTH REPORT OF THE HUMAN KIDNEY TRANSPLANT REGISTRY

1967 • 43 citations

Hyperglycemic, Hyperosmolar, Nonketoacidotic Diabetes: A Complication of Steroid and Immunosuppressive Therapy

1969 • 35 citations

THE EFFECT OF DIETARY COPPER ON RAT CARCINOGENESIS BY 3-METHOXY DYES. I. TUMORS INDUCED AT VARIOUS SITES BY FEEDING 3-METHOXY-4-AMINOAZOBENZENE AND ITS N-METHYL DERIVATIVE.

1964 • 33 citations

Progress in clinical renal homotransplantation.

1966 • 28 citations

Effects of pituitary hormones and prefeeding N-hydroxy-N-2-fluorenylacetamide on the metabolism of this carcinogen and on physiologic parameters.

1966 • 24 citations

RENAL TRANSPLANTATION FROM CADAVER DONORS

1968 • 23 citations

“Auto-immune” Chronic Hepatitis

1967 • 20 citations

Endocrine factors as determinants of the susceptibility of the liver to carcinogenic agents.

1968 • 19 citations

The metabolism of N-2-fluorenylhydroxyl-amine in male and female rats

1966 • 17 citations

Development of leukemia in rats by oral administration of N-nitrosobutylurea in the drinking water.

1969 • 14 citations

Immunity, Cancer, and Chemotherapy: Basic Relationships in the Cellular Level

1968 • 9 citations

The Effect of Immunosuppressive Drugs on Cellular Changes after Antigenic Stimulation

1967 • 8 citations

Treatment of refractory idiopathic thrombocytopenic purpura

1969 • 7 citations

Beeinflussung der Überlebenszeit von Hauthomotransplantaten bei Ratten durch Azathioprin

1969 • 2 citations

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Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor… (1970) – Toxicology and Applied Pharmacology | Metascience Observatory Explorer