The crystal structure of urease from Klebsiella aerogenes

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Crystal structure of the nickel–iron hydrogenase from Desulfovibrio gigas

1995 • 1,508 citations

Traitement statistique des erreurs dans la determination des structures cristallines

1952 • 1,284 citations

An efficient general-purpose least-squares refinement program for macromolecular structures

1987 • 871 citations

THE ISOLATION AND CRYSTALLIZATION OF THE ENZYME UREASE

1926 • 860 citations

Jack bean urease (EC 3.5.1.5). Metalloenzyme. Simple biological role for nickel

1975 • 784 citations

Development of a Mouse Model of Helicobacter pylori Infection that Mimics Human Disease

1995 • 574 citations

Atomic Structure of Adenosine Deaminase Complexed with a Transition-State Analog: Understanding Catalysis and Immunodeficiency Mutations

1991 • 430 citations

Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity

1991 • 419 citations

The evolution of α/β barrel enzymes

1990 • 378 citations

STRUCTURE, FUNCTION, REGULATION, AND ASSEMBLY OF <scp>D</scp>-RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE

1994 • 348 citations

Pathogenicity of Helicobacter pylori: a perspective

1993 • 327 citations

Jack bean urease (EC 3.5.1.5). V. On the mechanism of action of urease on urea, formamide, acetamide, N-methylurea, and related compounds

1980 • 215 citations

Three-Dimensional Structure of Phosphotriesterase: An Enzyme Capable of Detoxifying Organophosphate Nerve Agents

1994 • 213 citations

Sequence of the Klebsiella aerogenes urease genes and evidence for accessory proteins facilitating nickel incorporation

1990 • 212 citations

The structure of jack bean urease

1988 • 191 citations

Competitive Inhibitors of Klebsiella aerogenes Urease

1989 • 176 citations

Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis

1992 • 172 citations

[27] Multiwire area X-ray diffractometers

1985 • 163 citations

Requirement of Carbon Dioxide for in Vitro Assembly of the Urease Nickel Metallocenter

1995 • 149 citations

A least-squares refinement method for isomorphous replacement

1968 • 144 citations

Nucleotide sequence of two genes from Helicobacter pylori encoding for urease subunits

1990 • 138 citations

Purification and characterization of the nickel-containing multicomponent urease from Klebsiella aerogenes.

1987 • 118 citations

Jack bean urease (EC 3.5.1.5). III. The involvement of active-site nickel ion in inhibition by β-mercaptoethanol, phosphoramidate, and fluoride

1980 • 116 citations

Strategy for data collection from protein crystals using a multiwire counter area detector diffractometer

1985 • 114 citations

Structure-factor probabilities for related structures

1990 • 113 citations

Three‐dimensional, sequence order‐independent structural comparison of a serine protease against the crystallographic database reveals active site similarities: Potential implications to evolution and to protein folding

1994 • 103 citations

Structure of the Dinuclear Active Site of Urease. X-ray Absorption Spectroscopic Study of Native and 2-Mercaptoethanol-Inhibited Bacterial and Plant Enzymes

1994 • 79 citations

Site‐directed mutagenesis of Klebsiella aerogenes urease: Identification of histidine residues that appear to function in nickel ligation, substrate binding, and catalysis

1993 • 72 citations

An α/β-barrel full of evolutionary trouble

1993 • 71 citations

Preliminary crystallographic studies of urease from jack bean and from Klebsiella aerogenes

1992 • 57 citations

Site-directed mutagenesis of the active site cysteine in Klebsiella aerogenes urease.

1992 • 55 citations

Ulcers as an Infectious Disease

1993 • 54 citations

Reactivity of the essential thiol of Klebsiella aerogenes urease. Effect of pH and ligands on thiol modification

1991 • 50 citations

Identification of the essential cysteine residue in Klebsiella aerogenes urease.

1991 • 49 citations

Variable-temperature magnetic circular dichroism spectroscopy as a probe of the electronic and magnetic properties of nickel in jack bean urease

1991 • 43 citations

Cloning and expression of various staphylococcal genes encoding urease inStaphylococcus carnosus

1991 • 19 citations

Diethylpyrocarbonate reactivity ofKlebsiella aerogenes urease: Effect ofpH and active site ligands on the rate of inactivation

1993 • 19 citations