Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Pirenzepine distinguishes between different subclasses of muscarinic receptors

1980 • 1,299 citations

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

1973 • 1,284 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

1987 • 442 citations

Activation and attenuation of adenylate cyclase. The role of GTP-binding proteins as macromolecular messengers in receptor–cyclase coupling

1981 • 322 citations

Presence and regulation of tyrosinase activity in human neuroblastoma cell variants in vitro.

1985 • 110 citations

Differential receptor occupancy requirements for muscarinic cholinergic stimulation of inositol lipid hydrolysis in brain and in neuroblastomas.

1987 • 105 citations

Expression of neurotransmitter receptors and myc protooncogenes in subclones of a human neuroblastoma cell line.

1987 • 101 citations

Guanine nucleotide regulation of agonist binding to muscarinic cholinergic receptors. Relation to efficacy of agonists for stimulation of phosphoinositide breakdown and Ca2+ mobilization

1985 • 96 citations

A Putative M₃ Muscarinic Cholinergic Receptor of High Molecular Weight Couples to Phosphoinositide Hydrolysis in Human SK‐N‐SH Neuroblastoma Cells

1988 • 78 citations

Characterization of muscarinic receptors in guinea pig ileum longitudinal smooth muscle.

1988 • 70 citations

The Intact Human Neuroblastoma Cell (SH‐SY5Y) Exhibits High‐Affinity [³H]Pirenzepine Binding Associated with Hydrolysis of Phosphatidylinositols

1988 • 58 citations

Pharmacological Characterization of Cholinergic Receptors in a Human Neuroblastoma Cell Line

1986 • 57 citations

Separating receptor subtypes from their shadows

1988 • 53 citations

Phosphatidylinositol turnover in neuroblastoma cells: Regulation by bradykinin, acetylcholine, but not μ- and δ-opioid receptors

1986 • 42 citations

Recognition of muscarinic cholinergic receptors in human SK-N-SH neuroblastoma cells by quaternary and tertiary ligands is dependent upon temperature, cell integrity, and the presence of agonists.

1988 • 33 citations

80% of muscarinic receptors expressed by the NB‐OK 1 human neuroblastoma cell line show high affinity for pirenzepine and are comparable to rat hippocampus M1 receptors

1988 • 32 citations

Control of ion conductances by muscarinic receptors.

1988 • 28 citations

Muscarinic receptors coupled to phosphoinositide hydrolysis and elevated cytosolic calcium in a human neuroblastoma cell line SK‐N‐SH

1989 • 25 citations

Differential expression of α‐subunits of G‐proteins in human neuroblastoma‐derived cell clones

1987 • 25 citations