Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

Cancer Cell Cycles

1996 • 5,379 citations

NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer

2000 • 2,394 citations

Multivitamin Use, Folate, and Colon Cancer in Women in the Nurses' Health Study

1998 • 764 citations

Effects of DNA methylation on DNA-binding proteins and gene expression

1993 • 732 citations

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

1993 • 712 citations

Moderate Folate Depletion Increases Plasma Homocysteine and Decreases Lymphocyte DNA Methylation in Postmenopausal Women

1998 • 493 citations

Developing Inhibitors of the Epidermal Growth Factor Receptor for Cancer Treatment

2003 • 385 citations

Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis

1989 • 325 citations

The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis

1997 • 300 citations

Folate Intake and Carcinogenesis of the Colon and Rectum

1991 • 293 citations

Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats.

1992 • 225 citations

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

1997 • 156 citations

Micronutrients and cancer risk

1994 • 148 citations

Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer

2002 • 72 citations

Epithelial cell folate depletion occurs in neoplastic but not adjacent normal colon mucosa

1997 • 65 citations

Regulation of the expression of the tissue transglutaminase gene by DNA methylation

1997 • 65 citations

Folic acid inhibition of EGFR-mediated proliferation in human colon cancer cell lines

1999 • 57 citations

Regulation and Function of DNA Methylation in Vertebrates

1998 • 54 citations

Phage display: structure, assembly and engineering of filamentous bacteriophage M13

1994 • 43 citations

Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor Suppressor Genes

2003 • 39 citations

Folate and chemoprevention of colorectal cancer: is 5-methyl-tetrahydrofolate an active antiproliferative agent in folate-treated colon-cancer cells?

2001 • 34 citations

Aging

1995 • 30 citations

Tissue-specific methylation occurs in the essential promoter element of the tyrosine hydroxylase gene

1997 • 26 citations

Folic acid mediated attenuation of loss of heterozygosity of DCC tumor suppressor gene in the colonic mucosa of patients with colorectal adenomas

2003 • 25 citations

Cloning and Characterization of the Promoter Region of the Rat Epidermal Growth Factor Receptor Gene and Its Transcriptional Regulation by Nerve Growth Factor in PC12 Cells

2000 • 14 citations

Okadaic acid-mediated induction of the c-fos gene in estrogen receptor-negative human breast carcinoma cells utilized, in part, posttranscriptional mechanisms involving adenosine-uridine-rich elements.

2000 • 10 citations