A potent new dipeptide inhibitor of cell sickling and haemoglobin S gelation

Abnormal Adherence of Sickle Erythrocytes to Cultured Vascular Endothelium

1980 • 423 citations

Crystal structure of sickle-cell deoxyhemoglobin at 5 Å resolution

1975 • 336 citations

Molecular Mechanism of Red Cell "Sickling"

1966 • 206 citations

Supersaturation in sickle cell hemoglobin solutions.

1976 • 204 citations

Participation of hemoglobins A and F in polymerization of sickle hemoglobin.

1977 • 170 citations

Compensation in Haemolytic Anaemias caused by Abnormal Haemoglobins

1968 • 159 citations

Release of spectrin-free spicules on reoxygenation of sickled erythrocytes

1982 • 153 citations

Requirements for therapeutic inhibition of sickle haemoglobin gelation

1978 • 138 citations

Hemoglobin Interaction: Modification of Solid Phase Composition in the Sickling Phenomenon

1970 • 130 citations

Patterns of Nonelectrolyte Permeability in Human Red Blood Cell Membrane

1973 • 101 citations

Thermodynamic studies of polymerization of deoxygenated sickle cell hemoglobin.

1976 • 87 citations

Inhibition of sickle hemoglobin gelation by amino acids and related compounds

1978 • 84 citations

Amino acid transport in normal and glutathione-deficient sheep erythrocytes

1976 • 80 citations

The Concentration Dependence of the Oxygen Affinity of Haemoglobin S

1975 • 63 citations

Effects of amino acids on gelation kinetics and solubility of sickle hemoglobin

1977 • 58 citations

X-ray diffraction studies of fibers and crystals of deoxygenated sickle cell hemoglobin.

1979 • 53 citations

Sickle Hemoglobin Aggregation: A New Class of Inhibitors

1977 • 48 citations

Participation of haemoglobins A, F, A2 and C in polymerisation of haemoglobin S

1979 • 37 citations

Inhibition of sickling in erythrocytes by amino acids

1975 • 33 citations

Peptide inhibitors of sickle hemoglobin aggregation: effect of hydrophobicity

1980 • 28 citations

Studies of Peptide Antibiotics. I. Dipeptide Anhydrides as Models of Cyclic Peptide Antibiotics

1964 • 28 citations

Antisickling activity of amino acid benzyl esters.

1980 • 25 citations

Quantitative assessment of the noncovalent inhibition of sickle hemoglobin gelation by phenyl derivatives and other known agents

1979 • 24 citations

Oligopeptides as potential antiaggregation agents for deoxyhemoglobin S.

1977 • 18 citations

Acceleration of the rate of deoxyhemoglobin S polymerization by the erythrocyte membrane

1980 • 18 citations