Protein-ligand binding studies with a table-top, air-driven, high-speed centrifuge

Methods in Enzymology , Vol

1966 • 26,261 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Methods of Biochemical Analysis

1956 • 4,535 citations

Equilibrium Ultracentrifugation of Dilute Solutions^*

1964 • 3,399 citations

Measurement of protein-binding phenomena by gel filtration

1962 • 1,275 citations

Rapid Attainment of Sedimentation Equilibrium

1958 • 762 citations

YEAST ALCOHOL DEHYDROGENASE: MOLECULAR WEIGHT, COENZYME BINDING, AND REACTION EQUILIBRIA

1954 • 373 citations

Studies on the binding of RNA polymerase to polynucleotides

1966 • 361 citations

The Purification of Aspartate Transcarbamylase of Escherichia coli and Separation of Its Protein Subunits

1967 • 346 citations

Ultracentrifuge Studies with Absorption Optics. IV. Molecular Weight Determinations at the Microgram Level^*

1966 • 318 citations

Allosteric interactions in aspartate transcarbamylase. I. Binding of specific ligands to the native enzyme and its isolated subunits

1968 • 219 citations

A rapid and sensitive method for measuring the binding of radioactive ligands to proteins

1969 • 216 citations

THE BINDING OF DIPHOSPHOPYRIDINE NUCLEOTIDE BY GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE

1953 • 172 citations

The interaction of ribonuclease with purine and pyrimidine phosphates I. Binding of adenosine 5′-monophosphate to ribonuclease

1962 • 103 citations

Ultracentrifugation Studies with Absorption Optics. V. Analysis of Interacting Systems Involving Macromolecules and Small Molecules^*

1966 • 91 citations

Boundary Problems in the Sedimentation and Electrophoresis of Complex Systems in Rapid Reversible Equilibrium

1956 • 88 citations

STUDIES ON THE CALCIUM-PROTEIN RELATIONSHIP WITH THE AID OF THE ULTRACENTRIFUGE

1942 • 84 citations

A sedimentation equilibrium method for determining molecular weights of proteins with a tabletop high speed air turbine centrifuge.

1978 • 74 citations

Equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'-triphosphate and adenosine 5'-triphosphate

1973 • 65 citations

Interaction of Aspartate Transcarbamylase with Regulatory Nucleotides

1973 • 55 citations

Determination of ligand binding: partial and full saturation of aspartate transcarbamylase. Applicability of a filter assay to weakly binding ligands.

1976 • 47 citations

Spin-labeling studies of aspartate transcarbamylase. I. Effects of nucleotide binding and subunit separation

1970 • 46 citations

Asymmetry of binding and physical assignments of CTP and ATP sites in aspartate transcarbamoylase.

1977 • 46 citations

Molecular sieve studies of interacting protein systems

1971 • 39 citations

Calorimetric analysis of aspartate transcarbamylase from Escherichia coli. Binding of cytosine 5'-triphosphate and adenosine 5'-triphosphate

1975 • 35 citations

The binding of methyl orange to bovine serum albumin studied by frontal analysis in Sephadex chromatography

1971 • 23 citations

Difficulties encountered with an ultrafiltration method for measuring the binding of ligands to protein

1973 • 17 citations

Computer Simulation of Sedimentation Equilibrium Distributions for Systems Involving Heterogeneous Associations

1972 • 15 citations