Systemic Immunological Changes Induced by Administration of Grass Pollen Allergens via the Oral Mucosa during Sublingual Immunotherapy

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Allergen immunotherapy: Therapeutic vaccines for allergic diseases A WHO position paper☆☆☆★★★♢

1998 • 1,602 citations

Role of interleukin 10 in specific immunotherapy.

1998 • 980 citations

Oral tolerance: immune mechanisms and treatment of autoimmune diseases

1997 • 757 citations

Fatalities from immunotherapy (IT) and skin testing (ST)

1987 • 574 citations

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals.

1993 • 549 citations

Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ

1996 • 420 citations

Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs.

1991 • 390 citations

Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH₂ to TH₁ in T‐cell clones specific for Phi p 1, a major grass pollen allergen

1997 • 331 citations

Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding.

1994 • 318 citations

Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite

1986 • 265 citations

Sublingual‐swallow immunotherapy (SLIT) in patients with asthma due to house‐dust mites: a double‐blind, placebo‐controlled study

1999 • 240 citations

Efficacy of sublingual immunotherapy in patients with rhinitis and asthma due to house dust mite. A double-blind study.

1990 • 226 citations

Double‐blind, placebo‐controlled evaluation of sublingual immunotherapy with standardized olive pollen extract in pediatric patients with allergic rhinoconjunctivitis and mild asthma due to olive pollen sensitization

1998 • 190 citations

Immunotherapy of hay fever with ragweed antigen E: Comparisons with whole pollen extract and placebos

1968 • 187 citations

Clinical efficacy of sublingual‐swallow immunotherapy: a double‐blind, olacebo‐controlled trial of a standardized five‐grass‐pollen extract in rhinitis

1998 • 181 citations

Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients.

1995 • 161 citations

A double‐blind, placebo‐controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract

1994 • 159 citations

Absorption and distribution kinetics of the major Parietaria judaica allergen (Par j 1) administered by noninjectable routes in healthy human beings☆☆☆★

1997 • 141 citations

Antihistamine premedication in specific cluster immunotherapy: A double-blind, placebo-controlled study

1996 • 123 citations

Safety and efficacy of sublingual rush immunotherapy with grass allergen extracts. A double blind study.

1995 • 119 citations

Complementary DNA cloning of the major allergenPhl p I from timothy grass (Phleum pratense); recombinantPhl p I inhibits IgE binding to group I allergens from eight different grass species

1994 • 119 citations

Immunotherapy with sublingual birch pollen extract. A short-term double-blind placebo study.

1998 • 92 citations

T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): Evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens

1995 • 84 citations

Evaluation of immunotherapy‐induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting

1990 • 70 citations

Decrease of allergen‐specific T‐cell response induced by local nasal immunotherapy

1998 • 39 citations

[Systemic side effects in immunotherapy of allergic diseases--a comparative study].

1989 • 10 citations