Ultrastructural Localization of β-Actin and Amphoterin mRNA in Cultured Cells: Application of Tyramide Signal Amplification and Comparison of Detection Methods

Visualization of Single RNA Transcripts in Situ

1998 • 1,374 citations

FORMATION AND DETECTION OF RNA-DNA HYBRID MOLECULES IN CYTOLOGICAL PREPARATIONS

1969 • 1,214 citations

Catalyzed reporter deposition, a novel method of signal amplification application to immunoassays

1989 • 765 citations

Intracellular localization of messenger RNAs for cytoskeletal proteins

1986 • 639 citations

A cytoskeletal structure with associated polyribosomes obtained from HeLa cells

1977 • 530 citations

Transport and localization of exogenous myelin basic protein mRNA microinjected into oligodendrocytes.

1993 • 482 citations

Asymmetric Cell Division

2006 • 469 citations

Sorting of β-Actin mRNA and Protein to Neurites and Growth Cones in Culture

1998 • 444 citations

Visualization of detailed acetylcholinesterase fiber and neuron staining in rat brain by a sensitive histochemical procedure.

1986 • 429 citations

Translocation of RNA Granules in Living Neurons

1996 • 426 citations

Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast

1997 • 386 citations

Requirement of Microfilaments in Sorting of Actin Messenger RNA

1991 • 252 citations

mRNA Localization in Neurons: A Multipurpose Mechanism?

1997 • 248 citations

30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane.

1991 • 241 citations

β-Actin Messenger RNA Localization and Protein Synthesis Augment Cell Motility

1997 • 235 citations

mRNA and cytoskeletal filaments

1997 • 218 citations

Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation.

1993 • 218 citations

Beta actin and its mRNA are localized at the plasma membrane and the regions of moving cytoplasm during the cellular response to injury.

1991 • 216 citations

Protein translation components are colocalized in granules in oligodendrocytes

1995 • 215 citations

Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons.

1987 • 213 citations

Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts.

1994 • 173 citations

In situ hybridization at the electron microscope level: localization of transcripts on ultrathin sections of Lowicryl K4M-embedded tissue using biotinylated probes and protein A-gold complexes.

1986 • 164 citations

Ultrastructural visualization of cytoskeletal mRNAs and their associated proteins using double-label in situ hybridization.

1989 • 157 citations

Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy.

1992 • 154 citations

Association of poly(A) mRNA with microtubules in cultured neurons

1994 • 135 citations

Dendritic and Postsynaptic Localizations of Glycine Receptor α Subunit mRNAs

1997 • 105 citations

Aggregation of vasopressin mRNA in a subset of axonal swellings of the median eminence and posterior pituitary: light and electron microscopic evidence

1994 • 102 citations

Sorting of Messenger RNAs in the Cytoplasm: mRNA Localization and the Cytoskeleton

1996 • 101 citations

Components of the Nucleolar Processing Complex (Pre-rRNA, Fibrillarin, and Nucleolin) Colocalize during Mitosis and Are Incorporated to Daughter Cell Nucleoli

1995 • 69 citations

Use of 1.4-nm immunogold particles for immunocytochemistry on ultra-thin cryosections.

1994 • 66 citations

The immunofluorescent era of membrane traffic

1993 • 61 citations

The cytoskeleton in mRNA localization and cell differentiation

1997 • 59 citations

Adaptation of a non-radioactive in situ hybridization method to electron microscopy: detection of tenascin mRNAs in mouse cerebellum with digoxigenin-labelled probes and gold-labelled antibodies

1993 • 58 citations

Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution

1990 • 55 citations

Biotin and Digoxigenin as Labels for Light and Electron Microscopy in Situ Hybridization Probes: Where Do We Stand?

1997 • 55 citations

Ultrastructural Localization of Dendritic Messenger RNA in Adult Rat Hippocampus

1996 • 53 citations

Messenger RNAs in dendrites: localization, stability, and implications for neuronal function

1998 • 52 citations

Improvement of the electron microscopic detection of peroxidase activity by means of the silver intensification of the diaminobenzidine reaction in the rat nervous system

1982 • 45 citations

Distribution of myosin heavy chain mRNA in embryonic muscle tissue visualized by ultrastructural in situ hybridization

1991 • 44 citations

Effect of cytoarchitecture on the transport and localization of protein synthetic machinery

1993 • 41 citations

Ultrastructural non-radioactive in situ hybridization of GH mRNA in rat pituitary gland: pre-embedding vs ultra-thin frozen sections vs post-embedding.

1992 • 41 citations

Light and electron microscopic in situ hybridization: non-radioactive labeling and detection, double hybridization, and combined hybridization-immunocytochemistry.

1994 • 40 citations

High resolution distribution of mRNA within the cytoskeleton

1993 • 33 citations

Signal amplification at the ultrastructural level using biotinylated tyramides and immunogold detection

1997 • 33 citations

Post-embedding in situ hybridization for localization of viral nucleic acid in ultra-thin sections.

1993 • 31 citations

The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs: Association with novel electron-dense bodies

1997 • 30 citations

Electron microscopic detection of RNA sequences by non-radioactive in situ hybridization in the mollusk Lymnaea stagnalis.

1992 • 26 citations

Analysis of human mitochondrial transcripts using electron microscopic in situ hybridization

1991 • 25 citations

Ultrastructural localization of mRNA encoding for the EGF receptor in human breast cell cancer line BT20 by in situ hybridization.

1991 • 25 citations

A General RNA-Binding Protein Complex That Includes the Cytoskeleton-associated Protein MAP 1A

1998 • 23 citations

Ultrastructural localization of fibronectin mRNA in chick embryo by in situ hybridization using ³⁵S or biotin labeled cDNA probes

1990 • 22 citations

Immunocytochemistry and in situ hybridization in the electron microscope: combined application in the study of virus-infected cells

1995 • 21 citations

Localization of ribosomal RNA and Pbs21-mRNA in the sexual stages of Plasmodium berghei using electron microscope in situ hybridization.

1996 • 21 citations

Changes in the ultrastructural distribution of prolactin and growth hormone mRNAs in pituitary cells of female rats after estrogen and bromocriptine treatment, studied using in situ hybridization with biotinylated oligonucleotide probes

1995 • 20 citations

Saponin pre-treatment in pre-embedding electron microscopic in situ hybridization for detection of specific RNA sequences in cultured cells: a methodological study.

1995 • 18 citations

Amplification of the in situ hybridization signal by silver postintensification: the biotin-dUTP-streptavidin-peroxidase diaminobenzidine-silver-gold detection system

1991 • 12 citations

Electron microscopic location of mRNA in the rat kidney: improved post-embedding in situ hybridization.

1995 • 11 citations

Fine-structural localization of proenkephalin mRNAs in the hypothalamic magnocellular dorsal nucleus of the guinea pig: a comparison of radioisotopic and enzymatic in situ hybridization methods at the light- and electron-microscopic levels

1993 • 11 citations

Spatial Segregation of GαsmRNA and Vasopressin mRNA to Distinct Domains of the Rough Endoplasmic Reticulum within Secretory Neurons of the Rat Hypothalamus

1996 • 11 citations

Po Glycoprotein mRNA distribution in myelin-forming Schwann cells of the developing rat trigeminal ganglion

1990 • 8 citations

EGF-receptor RNA metabolism in the nucleus of A431 cells.

1996 • 3 citations