Effects of excess PTH on nonclassical target organs

Hypertension : pathophysiology, diagnosis, and management

1995 • 1,895 citations

A Parathyroid Hormone-Related Protein Implicated in Malignant Hypercalcemia: Cloning and Expression

1987 • 1,293 citations

A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide

1991 • 1,230 citations

Insulin resistance in uremia.

1981 • 579 citations

Defining the roles of parathyroid hormone-related protein in normal physiology

1996 • 576 citations

Identification and Functional Expression of a Receptor Selectively Recognizing Parathyroid Hormone, the PTH2 Receptor

1995 • 414 citations

Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acids during fetal development of rats.

1995 • 365 citations

Lipoprotein Metabolism and Renal Failure

1993 • 359 citations

Effect of parathyroid hormone on rat heart cells.

1981 • 335 citations

Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues.

1993 • 297 citations

Skeletal Resistance to Parathyroid Hormone in Renal Failure

1973 • 282 citations

A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia.

1994 • 254 citations

Textbook of nephrology

2013 • 244 citations

Expression of Messenger Ribonucleic Acids Encoding a Parathyroid Hormone-Like Peptide in Normal Human and Animal Tissues with Abnormal Expression in Human Parathyroid Adenomas

1988 • 217 citations

CONSERVATIVE SURGERY IN ALEPPO

1948 • 207 citations

Effect of Parathyroid Hormone on Osmotic Fragility of Human Erythrocytes

1982 • 184 citations

Central nervous system manifestations of hyperparathyroidism

1978 • 176 citations

Chronic continuous PTH infusion results in hypertension in normal subjects.

1986 • 165 citations

Parathyroid Hormone-Like Peptide in Normal and Neoplastic Human Endocrine Tissues*

1990 • 159 citations

EFFECT OF PARATHYROIDECTOMY ON LEFT-VENTRICULAR FUNCTION IN HÆMODIALYSIS PATIENTS

1980 • 153 citations

Mechanisms through which parathyroid hormone mediates its deleterious effects on organ function in uremia.

1994 • 152 citations

Effect of parathyroid hormone on energy metabolism ofskeletal muscle

1985 • 150 citations

The renal PTH/PTHrP receptor is down-regulated in rats with chronic renal failure

1994 • 144 citations

Overexpression of Parathyroid Hormone-related Protein in the Pancreatic Islets of Transgenic Mice Causes Islet Hyperplasia, Hyperinsulinemia, and Hypoglycemia

1996 • 143 citations

Effects of Parathyroid Hormone on Skeletal Muscle Protein and Amino Acid Metabolism in the Rat

1983 • 141 citations

Role of parathyroid hormone in the glucose intolerance of chronic renal failure.

1985 • 139 citations

Psychiatric Disorders in Primary Hyperparathyroidism

1968 • 138 citations

Effect of parathyroid hormone on myocardial energy metabolism in the rat

1985 • 137 citations

Immunological Identification and Distribution of Parathyroid Hormone-Like Protein Polypeptides in Normal and Malignant Tissues*

1991 • 134 citations

Hypotensive action of parathyroid hormone preparations on rats and dogs.

1980 • 133 citations

Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide.

1992 • 133 citations

Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms.

1993 • 131 citations

Excess parathyroid hormone adversely affects lipid metabolism in chronic renal failure

1990 • 130 citations

Blood Pressure Effects of Acute Hypercalcemia

1972 • 129 citations

Characterization of a novel parathyroid hormone (PTH) receptor with specificity for the carboxyl-terminal region of PTH-(1-84)

1995 • 127 citations

Impaired Phagocytosis in Dialysis Patients: Studies on Mechanisms

1991 • 126 citations

Hypotension and Cardiac Stimulation due to the Parathyroid Hormone-Related Protein, Humoral Hypercalcemia of Malignancy Factor*

1989 • 125 citations

Secondary hyperparathyroidism and cardiac hypertrophy in hemodialysis patients

1987 • 125 citations

Changes in the electroencephalogram in acute uremia. Effects of parathyroid hormone and brain electrolytes.

1975 • 121 citations

Down-regulation of tissue lipoprotein lipase expression in experimental chronic renal failure

1996 • 117 citations

Parathyroid Hormone as a Smooth Muscle Relaxant*

1989 • 116 citations

Distribution of parathyroid hormone-2 receptor messenger ribonucleic acid in rat.

1996 • 115 citations

Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation.

1991 • 115 citations

Diabetes mellitus, glucose tolerance and insulin response to glucose in patients with primary hyperparathyroidism before and after parathyroidectomy

1983 • 112 citations

Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines.

1995 • 111 citations

The Parathyroid Hormone-Like Peptide Gene is Expressed in the Normal and Neoplastic Human Endocrine Pancreas

1989 • 110 citations

Parathyroid hormone increases cytosolic calcium concentration in adult rat cardiac myocytes

1993 • 106 citations

Abnormalities in hepatic lipase in chronic renal failure: role of excess parathyroid hormone.

1996 • 104 citations

Excess PTH in CRF induces pulmonary calcification, pulmonary hypertension and right ventricular hypertrophy

1995 • 103 citations

The Influence of Hyperparathyroidism on Glucose Metabolism in Uremia*

1985 • 102 citations

Immunohistologic evaluation of parathyroid hormone-related protein in human lung cancer and normal tissue with newly developed monoclonal antibody

1991 • 101 citations

PARATHYROID HORMONE HAS A POSITIVE INOTROPIC ACTION IN THE RAT

1981 • 101 citations

Anemia and Secondary Hyperparathyroidism

1978 • 99 citations

Parathyroid Hormone-Parathyroid Hormone Related Protein Receptor Messenger RNA Is Present in Many Tissues besides the Kidney

1993 • 96 citations

Expression of parathyroid hormone related protein in normal skin and in tumours of skin and skin appendages

1989 • 96 citations

Uremic Cardiomyopathy: Potential Role of Vitamin D and Parathyroid Hormone

1984 • 93 citations

Immunocytochemical localization of parathyroid hormone-like peptide in the rat fetus.

1991 • 92 citations

Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain

1995 • 90 citations

Search for the Uremic Toxin

1978 • 90 citations

Parathyroid hormone-like protein is a secretory product of atrial myocytes.

1993 • 88 citations

Impotence in Patients with Uremia:

1977 • 88 citations

PTH/PTHrP receptor mRNA is down-regulated in epiphyseal cartilage growth plate of uraemic rats

1996 • 87 citations

On the mechanism of impaired insulin secretion in chronic renal failure.

1991 • 83 citations

Direct effect of parathyroid hormone on insulin secretion from pancreatic islets

1990 • 82 citations

Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acids during fetal development of rats

1995 • 80 citations

Parathyroid hormone (PTH) and PTH-related protein stimulate surfactant phospholipid synthesis in rat fetal lung, apparently by a mesenchymal-epithelial mechanism

1994 • 80 citations

Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues

1993 • 80 citations

Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP.

1994 • 77 citations

Chronic Renal Failure is a State of Cellular Calcium Toxicity

1993 • 74 citations

Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro.

1994 • 73 citations

Effect of parathyroid hormone on human T cell activation

1990 • 71 citations

Parathyroidectomy does not prevent the renal PTH/PTHrP receptor down-regulation in uremic rats

1995 • 71 citations

Binding of Parathyroid Hormone and Parathyroid Hormone-Related Protein to Vascular Smooth Muscle of Rabbit Renal Microvessels*

1990 • 70 citations

Analysis of PTHRP binding and signal transduction mechanisms in benign and malignant squamous cells

1992 • 70 citations

Parathyroid hormone receptors in circulating human mononuclear leukocytes.

1984 • 68 citations

Specific inhibition of long-lasting, L-type calcium channels by synthetic parathyroid hormone.

1990 • 66 citations

Parathyroid Hormone Modulates Angiotensin II-Induced Aldosterone Secretion from the Adrenal Glomerulosa Cell*

1991 • 66 citations

Pulmonary calcification in hemodialyzed patients detected by technetium-99m diphosphonate scanning

1980 • 65 citations

Insulin release from pancreatic islets: Effects of CRF and excess PTH

1988 • 65 citations

Chronic renal failure, parathyroid hormone and fatty acids oxidation in skeletal muscle

1988 • 64 citations

Parathyroid hormone-related protein is a possible autocrine growth inhibitor for lymphocytes

1990 • 63 citations

Coronary Atherosclerotic Smooth Muscle Cells Overexpress Human Parathyroid Hormone-Related Peptides

1994 • 62 citations

Effects of PTH(1-34) on Blood Pressure, Renal Function, and Hormones in Essential Hypertension The Altered Pattern of Reactivity May Counteract Raised Blood Pressure

1997 • 61 citations

On the lipolytic action of parathyroid hormone in man

1976 • 60 citations

Stimulatory effects of interleukin-induced activation of the hypothalamo-pituitary-adrenal axis on gonadotropin secretion in ovariectomized monkeys replaced with estradiol.

1994 • 59 citations

PTH-PTHrP Receptor mRNA Is Downregulated in Chronic Renal Failure

1994 • 59 citations

Cardiovascular responsiveness to parathyroid hormone (PTH) and PTH-related protein in genetic hypertension.

1992 • 56 citations

The Toxic Effects of Parathyroid Hormone in Uremia

1983 • 56 citations

The effects of parathyroid hormone on L‐type voltage‐dependent calcium channel currents in vascular smooth muscle cells and ventricular myocytes are mediated by a cyclic AMP dependent mechanism

1991 • 53 citations

Reversible Resistance to the Renal Action of Parathyroid Hormone in Man

1976 • 53 citations

Mechanisms of impaired insulin secretion after chronic excess of parathyroid hormone

1990 • 52 citations

Response of adrenal cells to parathyroid hormone stimulation

1987 • 51 citations

Parathyroid hormone inhibits B cell proliferation

1990 • 51 citations

Relation between parathyroid hormone and cardiac function in long-term hemodialysis patients.

1995 • 51 citations

Fatty acid oxidation in the myocardium: Effects of parathyroid hormone and CRF

1988 • 49 citations

Evidence of Impaired T Cell Function in Hemodialysis Patients: Potential Role for Secondary Hyperparathyroidism

1990 • 49 citations

Altered cytosolic calcium homeostasis in rat cardiac myocytes in CRF

1994 • 47 citations

Distribution of parathyroid hormone-2 receptor messenger ribonucleic acid in rat

1996 • 46 citations

Abnormal norepinephrine uptake and release in brain synaptosomes in chronic renal failure

1989 • 46 citations

Impaired phagocytosis in chronic renal failure is mediated by secondary hyperparathyroidism

1992 • 44 citations

Parathyroid Hormone: A Uremic Toxin

1987 • 44 citations

Effect of Parathyroid Hormone on Random Migration of Human Polymorphonuclear Leukocytes

1988 • 43 citations

Down-regulation of PTH-PTHrP receptor of heart in CRF: Role of [Ca2+]i

1995 • 42 citations

Chronic parathyroid hormone excess in vivo increases resting levels of cytosolic calcium in brain synaptosomes

1991 • 38 citations

Cardiac Dysfunction in Chronic Uremia

1992 • 38 citations

The Role of Secondary Hyperparathyroidism in the Anemia of Chronic Renal Failure

1983 • 38 citations

Characterization of a novel parathyroid hormone (PTH) receptor with specificity for the carboxyl-terminal region of PTH-(1-84)

1995 • 35 citations

Enhancement of the stimulatory effect of calcium on aldosterone secretion by parathyroid hormone.

1994 • 34 citations

Parathyroid hormone selectively inhibits L‐type calcium channels in single vascular smooth muscle cells of the rat.

1991 • 34 citations

Effect of Chronic Renal Failure on Heart

1986 • 31 citations

Parathyroid Hormone and the Cellular Immune System

1995 • 30 citations

Effects of verapamil on the abnormalities in fatty acid oxidation of myocardium

1989 • 30 citations

Sequence analysis of hypothalamic parathyroid hormone messenger ribonucleic acid.

1995 • 30 citations

The mechanisms responsible for the PTH-induced rise in cytosolic calcium in various cells are not uniform.

1995 • 29 citations

Immunocytochemical Detection of Parathyroid Hormone-Related Protein in Vascular Endothelial Cells

1994 • 29 citations

Parathyroid hormone: neural and neuroendocrine perspectives

1993 • 29 citations

Parathyroid hormone raises cytosolic calcium in pancreatic islets: Study on mechanisms

1993 • 29 citations

Verapamil Prevents Chronic Renal Failure-Induced Abnormalities in Lipid Metabolism

1993 • 28 citations

Secondary hyperparathyroidism and the immune system in chronic renal failure.

1991 • 27 citations

Deficient Prolactin Response to Parathyroid Hormone in Hypocalcemic and Normocalcemic Pseudohypoparathyroidism

1981 • 27 citations

Comparison between the Plasma Concentrations of Prolactin and Parathyroid Hormone in Normal Subjects and in Patients with Hyperparathyroidism or Hyperprolactinemia*

1982 • 27 citations

Correction of glucose intolerance and the impaired insulin release of chronic renal failure by verapamil

1989 • 26 citations

The changes in contractile status of single vascular smooth muscle cells and ventricular cells induced by bPTH-(1–34)

1993 • 25 citations

Effects of hypercalcemia and parathyroid hormone on blood pressure in normal and renal-failure rats

1986 • 25 citations

Parathyroid hormone dependent T cell proliferation in uremic rats

1993 • 25 citations

Parathyroid Hypertensive Factor, a Circulating Factor in Animal and Human Hypertension

1991 • 25 citations

Derangements in acetylcholine metabolism in brain synaptosomes in chronic renal failure

1993 • 25 citations

Parathyroid hormone binding sites in the brain

1993 • 24 citations

Influence of 1,25 dihydroxycholecalciferol on sexual dysfunction and related endocrine parameters in patiens on maintenance hemodialysis.

1980 • 23 citations

Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro

1994 • 22 citations

Effect of treatment of hemodialysis patients with nifedipine on metabolism and function of polymorphonuclear leukocytes

1995 • 22 citations

In vitro Effect of PTH on Normal T Cell Functions

1988 • 22 citations

Decreased O2 consumption by PMNL from humans and rats with CRF: Role of secondary hyperparathyroidism

1992 • 20 citations

New Actions of Parathyroid Hormone

1989 • 19 citations

Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines

1995 • 19 citations

Impaired potassium-induced insulin secretion in chronic renal failure

1991 • 19 citations

Effect of chronic renal failure and parathyroid hormone on phospholipid content of brain synaptosomes

1989 • 19 citations

Evidence for a role of PTH in the reduced pressor response to norepinephrine in chronic renal failure

1985 • 18 citations

Anemia and secondary hyperparathyroidism

1978 • 18 citations

Chronology of cellular events leading to derangements in function of pancreatic islets in chronic renal failure.

1992 • 17 citations

Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin- II and PTHrP

1994 • 17 citations

PTH, chronic renal failure and myocardium.

1995 • 17 citations

Impaired in vivo antibody production in CRF rats: Role of secondary hyperparathyroidism

1991 • 17 citations

Nifedipine reverses the abnormalities in [Ca2+]i and proliferation of B cells from dialysis patients

1996 • 17 citations

Verapamil corrects abnormalities in norepinephrine metabolism of brain synaptosomes in CRF

1990 • 17 citations

Calcium-Dependent Aldosterone Secretion in Anephric and Nonnephrectomized Patients on Regular Hemodialysis*

1978 • 15 citations

Abnormal leucine-induced insulin secretion in chronic renal failure

1994 • 15 citations

Identification and characterization of parathyroid hormone receptors on dog kidney, human kidney, chick bone and human dermal fibroblast. A comparative study of functional and structural properties

1989 • 15 citations

Effect of Verapamil on CRF-Induced Abnormalities in Phospholipid Contents of Brain Synaptosomes

1990 • 14 citations

Hyperparathyroidism and Hypotestosteronemia of Acute Renal Failure

1988 • 13 citations

Elevated cytosolic calcium of adipocytes in chronic renal failure

1995 • 13 citations

Cardiovascular responsiveness to parathyroid hormone (PTH) and PTH- related protein in genetic hypertension

1992 • 13 citations

Effect of secondary hyperparathyroidism on the anaemia of end-stage renal failure: in vivo and in vitro studies.

1983 • 12 citations

Sequence analysis of hypothalamic parathyroid hormone messenger ribonucleic acid

1995 • 11 citations

Parathyroid hormone analogues inhibit calcium mobilization in cultured vascular cells.

1994 • 11 citations

Excessive level of parathyroid hormone may induce the reduction of recombinant human erythropoietin effect on renal anemia.

1995 • 10 citations

Adenylate cyclase of human fat cell ghosts

1979 • 10 citations

Calcium-Stimulated Vasopressin Secretion in Uremic Patients: An Effect Mediated via Parathyroid Hormone?*

1980 • 9 citations

Verapamil Reverses Glucose Intolerance in Preexisting Chronic Renal Failure: Studies on Mechanisms

1992 • 8 citations

Parathyroid hormone and B cell function in dialysis patients and experimental chronic renal failure.

1995 • 6 citations

Parathyroid Hormone and the Myocardiopathy of Chronic Renal Failure

1992 • 5 citations

Parathyroid hormone and hypothalamo-pituitary function.

1995 • 4 citations

Parathyroid Hormone as a Uremic Toxin

2020 • 3 citations

Control of calcium channels in neuroblastoma cells (N1E-115)

1990 • 2 citations

STIMULATION OF ENZYME ACTIVITY BY PARATHYROID HORMONE

1977 • 1 citations