Desmethylnafoxidine aziridine: An electrophilic affinity label for the estrogen receptor with high efficiency and selectivity

Rapid chromatographic technique for preparative separations with moderate resolution

1978 • 5,766 citations

Acylation, methylation, and carboxyalkylation of olefins by Group VIII metal derivatives

1968 • 745 citations

Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent

1979 • 459 citations

Quantitative dealkylation of alkyl ethers via treatment with trimethylsilyl iodide. A new method for ether hydrolysis

1977 • 413 citations

Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.

1984 • 274 citations

Quantitative dealkylation of alkyl esters via treatment with trimethylsilyl iodide. A new method for ester hydrolysis

1977 • 257 citations

Hydroxylated metabolites of tamoxifen are formed in vivo and bound to estrogen receptor in target tissues.

1981 • 235 citations

Photoaffinity labels for estrogen binding proteins of rat uterus

1973 • 220 citations

Effects of estrogens and antiestrogens on estrogen receptor dynamics and the induction of progesterone receptor in MCF-7 human breast cancer cells.

1982 • 212 citations

The Metabolism of Tamoxifen (I.C.I. 46,474) Part I : In Laboratory Animals

1973 • 181 citations

Activated metals. IV. Preparation and reactions of highly reactive magnesium metal

1974 • 175 citations

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen

1982 • 169 citations

Efficient and highly selective covalent labeling of the estrogen receptor with [3H]tamoxifen aziridine.

1983 • 154 citations

Characterization of the Estrogen Receptor and Its Dynamics in MCF-7 Human Breast Cancer Cells Using a Covalently Attaching Antiestrogen*

1984 • 98 citations

Boron trihalide-methyl sulfide complexes as convenient reagents for dealkylation of aryl ethers

1980 • 97 citations

Facile geometric isomerization of phenolic non-steroidal estrogens and antiestrogens: Limitations to the interpretation of experiments characterizing the activity of individual isomers

1985 • 89 citations

Synthesis of the (E) and (Z) isomers of the antiestrogen tamoxifen and its metabolite, hydroxytamoxifen, in tritium-labeled form

1982 • 89 citations

Diaryliodonium Salts. XVII. The Phenylation of 1,3-Indandiones

1962 • 57 citations

Estrogen photoaffinity labels. 2. Reversible binding and covalent attachment of photosensitive hexestrol derivatives to the uterine estrogen receptor

1977 • 46 citations

Antiestrogen Stimulation of the Production of a 37,000 Molecular Weight Secreted Protein and Estrogen Stimulation of the Production of a 32,000 Molecular Weight Secreted Protein in MCF-7 Human Breast Cancer Cells*

1987 • 45 citations

Affinity labelling of steroid hormone receptors

1986 • 43 citations

Hydroxyalkylation with Cyclic Alkylene Esters. I. Synthesis of Hydroxyethylapocupreine

1947 • 41 citations

Diaryliodonium Salts. XVIII. The Phenylation of Esters in t-Butyl Alcohol^1-3

1963 • 38 citations

Mammalian Antifertility Agents. III. 1-Aryl-2-phenyl-1,2,3,4-tetrahydro-1-naphthols, 1-Aryl-2-phenyl-3,4-dihydronaphthalenes, and Their Derivatives¹

1966 • 36 citations

Reagents for photoaffinity labeling of estrogen binding proteins. Synthesis of some azide and diazo derivatives of estradiol, estrone, and hexestrol

1973 • 34 citations

Mammalian antifertility agents. VI. A novel sequence for the preparation of 1,2-disubstituted 3,4-dihydronaphthalenes

1969 • 32 citations

TAMOXIFEN AZIRIDINES: EFFECTIVE INACTIVATORS OF THE ESTROGEN RECEPTOR

1981 • 29 citations

Affinity Labeling of Receptors for Steroid and Thyroid Hormones

1984 • 29 citations

Chemically reactive estrogens: synthesis and estrogen receptor interactions of hexestrol ether derivatives and 4-substituted deoxyhexestrol derivatives bearing alkylating functions

1981 • 26 citations

Affinity Labeling as a Technique in Determining Hormone Mechanisms

1977 • 19 citations

Synthesis of medium-ring benzoic acid lactones

1968 • 18 citations