Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells

Single-Channel Recording

1995 • 2,565 citations

Single-Channel Recording

1995 • 1,028 citations

Binding, gating, affinity and efficacy: The interpretation of structure‐activity relationships for agonists and of the effects of mutating receptors

1998 • 880 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1995 • 549 citations

Serotonin and alcohol intake, abuse, and dependence: Findings of animal studies

1994 • 380 citations

Serotonin and alcohol intake, abuse, and dependence: Clinical evidence

1994 • 343 citations

Ethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in neuroblastoma cells and isolated adult mammalian neurons.

1991 • 210 citations

Clinical Efficacy of the 5‐HT₃ Antagonist Ondansetron in Alcohol Abuse and Dependence

1994 • 192 citations

The 5-HT3 Receptor Channel

1995 • 180 citations

Ethanol potentiation of GABA_A receptors requires phosphorylation of the alternatively spliced variant of the γ2 subunit

1992 • 178 citations

MDL 72222, A SELECTIVE 5-HT3 RECEPTOR ANTAGONIST, SUPPRESSES VOLUNTARY ETHANOL CONSUMPTION IN ALCOHOL-PREFERRING RATS

1991 • 152 citations

Ethanol Increases GABAA Responses in Cells Stably Transfected with Receptor Subunits

1995 • 121 citations

Alcohols and anesthetics enhance the function of 5-hydroxytryptamine3 receptors expressed in Xenopus laevis oocytes.

1994 • 119 citations

The role of 5-HT3 receptors in drug dependence

1995 • 112 citations

Ethanol potentiation of 5-HT3 receptor-mediated ion current in NCB-20 neuroblastoma cells

1991 • 107 citations

Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: a preliminary study in healthy male volunteers

1993 • 100 citations

Actions of general anaesthetics on 5‐HT₃ receptors in N1E‐115 neuroblastoma cells

1996 • 90 citations

Effect of the 5-HT3 antagonist ondansetron on voluntary ethanol intake in rats and mice maintained on a limited access procedure

1995 • 83 citations

Alcohols potentiate ion current mediated by recombinant 5-HT3RA receptors expressed in a mammalian cell line

1994 • 77 citations

Alcohols potentiate the function of 5‐HT₃ receptor‐channels on NCB‐20 neuroblastoma cells by favouring and stabilizing the open channel state

1998 • 74 citations

Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor.

1994 • 71 citations

The dopamine response in mouse neuroblastoma cells is mediated by serotonin 5HT3 receptors

1986 • 56 citations

Selection of distinct conformational states of the 5‐HT₃ receptor by full and partial agonists

1996 • 54 citations

Pharmacologic characteristics of potentiation of 5-HT3 receptors by alcohols and diethyl ether in NCB-20 neuroblastoma cells.

1996 • 47 citations

The interaction of trichloroethanol with murine recombinant 5‐HT₃ receptors

1995 • 45 citations

Trichloroethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in nodose ganglion neurons from the adult rat.

1993 • 38 citations

Effects of alcohols and volatile anesthetics on the activation of nicotinic acetylcholine receptor channels.

1994 • 34 citations

Increasing effect of ethanol on 5-HT3 receptor-mediated 14C-guanidinium influx in N1E-115 neuroblastoma cells

1995 • 28 citations

Electrophysiological consequences of ligand binding to the desensitized 5‐HT3 receptor in mammalian NG108‐15 cells.

1996 • 24 citations

Microtubule Depolymerization Inhibits Ethanol‐Induced Enhancement of GABA_A Responses in Stably Transfected Cells

1996 • 21 citations

Ethanol Fails to Modify [³H]GR65630 Binding to 5‐HT₃ Receptors in NCB‐20 Cells and in Rat Cerebral Membranes

1991 • 20 citations

Mutation of Putative Phosphorylation Sites in the 5-Hydroxytryptarnine3 Receptor Does Not Eliminate Its Modulation by Ethanol

1999 • 6 citations

Alcohol and the 5-HT3 Receptor

1999 • 1 citations