Complement Research

A biochemical abnormality in hereditary angioneurotic edema

1963 • 955 citations

Quantitative Micro-Complement Fixation and Its Use in the Study of Antigenic Structure by Specific Antigen-Antibody Inhibition

1961 • 657 citations

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum

1966 • 651 citations

CHROMATOGRAPHIC RESOLUTION OF THE FIRST COMPONENT OF HUMAN COMPLEMENT INTO THREE ACTIVITIES

1963 • 377 citations

Complement Fixation on Cell Surfaces by 19 S and 7 S Antibodies

1965 • 336 citations

PROPERTIES OF GUINEA PIG 7S ANTIBODIES

1963 • 302 citations

STUDIES ON THE MECHANISM OF HYPERSENSITIVITY PHENOMENA

1957 • 226 citations

Assay and Properties of Serum Inhibitor of C'1-Esterase

1959 • 224 citations

Further studies on the chemotactic factor of complement and its formation in vivo.

1966 • 222 citations

PROPERTIES OF GUINEA PIG 7S ANTIBODIES

1963 • 218 citations

EFFECT OF ANTIBODY AND COMPLEMENT ON PERMEABILITY CONTROL IN ASCITES TUMOR CELLS AND ERYTHROCYTES

1959 • 204 citations

Hemolysin Titration Based on Fixation of the Activated First Component of Complement: Evidence That One Molecule of Hemolysin Suffices to Sensitize an Erythrocyte

1965 • 185 citations

Chromatographic Separation of the First Component of Complement and Its Assay on a Molecular Basis

1963 • 183 citations

Lesions in Erythrocyte Membranes Caused by Immune Hæmolysis

1964 • 169 citations

EXPERIMENTAL GLOMERULONEPHRITIS

1964 • 162 citations

COMPONENTS OF GUINEA PIG COMPLEMENT

1963 • 153 citations

Hereditary deficiency of the second component of complement (C'2) in man.

1966 • 152 citations

Serum Levels of Beta1C Globulin, a Complement Component, in the Nephritides, Lipoid Nephrosis, and Other Conditions *

1964 • 144 citations

Effects of Low Ionic Strength on Immune Hemolysis

1963 • 135 citations

C'1 ESTERASE EFFECT ON ACTIVITY AND PHYSICOCHEMICAL PROPERTIES OF THE FOURTH COMPONENT OF COMPLEMENT

1965 • 131 citations

Detection of Hereditary Angioneurotic Edema by Demonstration of a Reduction in the Second Component of Human Complement

1965 • 123 citations

THE MACROMOLECULAR NATURE OF THE FIRST COMPONENT OF HUMAN COMPLEMENT

1964 • 122 citations

C'-1 fixation by human isoagglutinins: fixation of C'-1 by gamma-G and gamma-M but not by gamma-A antibody.

1966 • 106 citations

STUDIES ON THE ACTIVATION OF A PROESTERASE ASSOCIATED WITH PARTIALLY PURIFIED FIRST COMPONENT OF HUMAN COMPLEMENT

1958 • 106 citations

STUDIES ON THE MECHANISM OF HYPERSENSITIVITY PHENOMENA

1959 • 101 citations

IDENTIFICATION OF THE COMPONENTS OF COMPLEMENT PARTICIPATING IN THE ANTIGLOBULIN REACTION.

1963 • 80 citations

IMMUNE LYSIS OF NORMAL HUMAN AND PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELLS

1966 • 79 citations

Immune lysis of normal human and paroxysmal nocturnal hemoglobinuria (PNH) red blood cells. II. The role of complement components in the increased sensitivity of PNH red cells to immune lysis.

1966 • 78 citations

Serologic tests for inflammation

1956 • 60 citations

STRUCTURAL CHANGES PRODUCED IN BROWN-PEARCE CARCINOMA CELLS BY MEANS OF A SPECIFIC ANTIBODY AND COMPLEMENT

1953 • 59 citations

Studies on the Second Component of Complement. I. The Reaction between EAC'1,4 and C'2: Evidence on the Single Site Mechanism of Immune Hemolysis and Determination of C'2 on a Molecular Basis.

1961 • 58 citations

Differences in Serum Complement Activity among Inbred Strains of Mice

1964 • 58 citations

ACTION OF THE FIRST COMPONENT OF COMPLEMENT. ACTIVITATION OF C'1 TO C'1A IN THE HEMOLYTIC SYSTEM.

1964 • 56 citations

The Isolation and Characterization of a Ninth Component of Hemolytic Complement, C′3f

1966 • 55 citations

Concerning the mechanism of complement action. V. The early steps in immune hemolysis.

1960 • 55 citations

Interaction of Autologous Complement with Red Cells in the Absence of Antibody.

1964 • 53 citations

C′2ad, an inactive derivative of C′2 released during decay of EAC′4,2a

1966 • 50 citations

Mechanism of Immune Hemolysis: Recognition of Two Steps in the Conversion of EAC' 1,4,2 to E*

1958 • 50 citations

Reversible adsorption of C′2 by EAC′4: Role of Mg2+, enumeration of competent SAC′4, two-step nature of C′2a fixation and estimation of its efficiency

1966 • 47 citations

Sur l'agglutination et la dissolution des globules rouges par le sérum d'animaux injectés de sang défibriné

1898 • 37 citations

Beta-1C-Globulin: Metabolism in Glomerulonephritis

1966 • 37 citations

Catalysis of C'2 fixation by C'la. Reaction kinetics, competitive inhibition by TAMe, and transferase hypothesis of the enzymatic action of C'la on C'2, one of its natural substrates.

1965 • 36 citations

Forssman Antigen and Antibody: Preparation of Water Soluble Antigen and Measurement of Antibody Concentration by Precipitin Analysis, by C′1a Fixation and by Hemolytic Activity

1966 • 35 citations

STUDIES ON IMMUNE HUMAN HEMOLYSIS

1961 • 33 citations

Antibody-Complement Complexes

1965 • 29 citations

Steroids and Serum Complement in Mice: Influence of Hydrocortisone, Diethylstilbestrol, and Testosterone

1966 • 28 citations

BETA-1-C-GLOBULIN: AN "ACUTE PHASE" SERUM REACTANT OF HUMAN SERUM.

1965 • 25 citations

Immunological Histamine Release from Rat Mast Cells in vitro: Effect of Age of Cell Donor

1965 • 24 citations

Mouse Complement: Influence of Sex Hormones on Its Activity

1966 • 22 citations

Studies on the Second Component of Complement. II. The Nature of the Decay of EAC'1,4,2.

1961 • 21 citations

Studies on Immune Factors Occurring in Sera of Chickens Against the Crithidia Stage of Trypanosoma Cruzi

1959 • 21 citations

Kinetic studies on immune hemolysis. III. Description of a terminal process which follows the Ca++ and Mg++ reaction steps in the action of complement on sensitized erythrocytes.

1954 • 18 citations

A Mathematical Theory of Immune Hemolysis

1951 • 17 citations

Complement fixation in diseased tissues. II. Fixation of guinea pig complement in renal lesions of systemic lupus erythematosus.

1963 • 17 citations

Differences in Complement Titers of Serums from Spaced Bleedings in Guinea Pigs

1964 • 5 citations

A new complement fixation test: Enumeration of antibodies at cell surfaces on a molecular basis

1966 • 5 citations

Complement Fixation: A Modified Procedure Designed to Eliminate Anticomplementary and Proeomplementary Effects.

1965 • 2 citations

Kinetics of 86Rb and hemoglobin release from erythrocytes following membrane damage by antibody and complement

1966 • 1 citations