3,4-Diaminopyridine, an orphan drug, in the symptomatic treatment of Lambert-Eaton myasthenic syndrome

THE LAMBERT-EATON MYASTHENIC SYNDROME

1988 • 673 citations

QUANTAL COMPONENTS OF END‐PLATE POTENTIALS IN THE MYASTHENIC SYNDROME*

1971 • 304 citations

3,4-Diaminopyridine in the Treatment of Lambert–Eaton Myasthenic Syndrome

1989 • 296 citations

On the release of transmitter at normal, myasthenia gravis and myasthenic syndrome affected human end‐plates.

1980 • 212 citations

IgG from Patients with Lambert-Eaton Syndrome Blocks Voltage-Dependent Calcium Channels

1988 • 194 citations

Potency of 3,4-Diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes

1980 • 176 citations

Autoimmunity to the voltage-gated calcium channel underlies the Lambert-Eaton myasthenic syndrome, a paraneoplastic disorder

1989 • 167 citations

Treatment with oral 4‐aminopyridine in disorders of neuromuscular transmission

1981 • 125 citations

Short report: 4-Aminopyridine--a new drug tested in the treatment of Eaton-Lambert syndrome

1977 • 111 citations

Treatment of Larnbert‐Eaton syndrome

1984 • 108 citations

Evaluation of 4-aminopyridine and 3,4-diaminopyridine penetrability into cerebrospinal fluid in anesthetized rats

1984 • 66 citations

Practical aspects of 3,4-diaminopyridine treatment of the Lambert-Eaton myasthenic syndrome

2009 • 63 citations

Guanidine and Neuromuscular Transmission

1975 • 56 citations

CLINICAL, NEUROPHYSIOLOGICAL AND MORPHOLOGICAL FINDINGS IN EATON LAMBERT SYNDROME

2009 • 55 citations

Lambert‐eaton myasthenic syndrome: Immunoglobulin G inhibition of Ca²⁺ flux in tumor cells correlates with disease severity

1989 • 45 citations

Guanidine and germine in Eaton‐Lambert syndrome

1976 • 45 citations

Decreased calcium currents in motor nerve terminals of mice with Lambert‐Eaton myasthenic syndrome.

1995 • 43 citations

Guanidine and Neuromuscular Transmission

1975 • 39 citations

Review of Evidence for Loss of Motor Nerve Terminal Calcium Channels in Lambert‐Eaton Myasthenic Syndromea

1991 • 35 citations

3,4‐Diaminopyridine in Lambert‐Eaton Myasthenic Syndrome and Myasthenia Gravisa

1993 • 30 citations

[Changes in transmitter release at frog neuromuscular junction induced by 4-aminopyridine].

1975 • 19 citations

The mode of action of guanidine on mouse motor nerve terminals

1988 • 15 citations

Lambert-Eaton Myasthenic Syndrome: Pathogenesis and Treatment

1994 • 8 citations

[Long-term treatment of Lambert-Eaton syndrome by 3, 4 diaminopyridine].

1992 • 4 citations

Lambert-Eaton myasthenic syndrome: evaluation of movement performance following drug therapy.

1994 • 1 citations