The Effectiveness of the Xanthine Oxidase Inhibitor Allopurinol in the Treatment of Gout

Potentiation by inhibition of drug degradation : 6-substituted purines and xanthine oxidase

1963 • 305 citations

URIC ACID PRODUCTION IN GOUT

1961 • 230 citations

Effect of allopurinol (4-Hydroxypyrazolo-(3,4-d)pyrimidine) on serum and urinary uric acid in primary and secondary gout

1964 • 228 citations

Effects of a xanthine oxidase inhibitor on thiopurine metabolism, hyperuricemia and gout

2001 • 158 citations

THE RENAL EXCRETION OF URIC ACID IN GOUT

1962 • 103 citations

PYRAZOLOPYRIMIDINES AS INHIBITORS AND SUBSTRATES OF XANTHINE OXIDASE

1957 • 96 citations

Augmentation of the incorporation of hypoxanthine into nucleic acids by the administration of an inhibitor of xanthine oxidase

1963 • 79 citations

Gout: Six-year follow-up on probenecid (benemid) therapy

1959 • 54 citations

Enzyme Defect in a Case of Xanthinuria

1964 • 54 citations

SUPPRESSION OF URIC ACID SYNTHESIS IN THE GOUTY HUMAN BY THE USE OF 6-DIAZO-5-OXO-L-NORLEUCINE*

1960 • 40 citations

Mobilization of gouty tophi by protracted use of uricosuric agents

1951 • 35 citations

Utilization of hypoxanthine, adenine and 4-amino-5-imidazole-carboxamide for uric acid synthesis in man.

1959 • 31 citations