Do not underestimate the power of antibodies—lessons from adoptive transfer of antibodies against HIV

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1994 • 2,529 citations

Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

1999 • 1,428 citations

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

2000 • 1,247 citations

Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine

2001 • 1,128 citations

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

1996 • 1,111 citations

Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination

2000 • 901 citations

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection

2000 • 861 citations

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

2001 • 791 citations

Protection of Macaques against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies

1999 • 786 citations

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

2000 • 693 citations

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

2002 • 670 citations

Antibody Protects Macaques against Vaginal Challenge with a Pathogenic R5 Simian/Human Immunodeficiency Virus at Serum Levels Giving Complete Neutralization In Vitro

2001 • 665 citations

Quantifying the uncertainty in forecasts of anthropogenic climate change

2000 • 652 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

A Potent Cross-Clade Neutralizing Human Monoclonal Antibody against a Novel Epitope on gp41 of Human Immunodeficiency Virus Type 1

2001 • 516 citations

A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys

1996 • 501 citations

Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D

1994 • 214 citations

Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies

2001 • 163 citations

Postnatal Passive Immunization of Neonatal Macaques with a Triple Combination of Human Monoclonal Antibodies against Oral Simian-Human Immunodeficiency Virus Challenge

2001 • 156 citations

Infection and Pathogenicity of Chimeric Simian‐Human Immunodeficiency Viruses in Macaques: Determinants of High Virus Loads and CD4 Cell Killing

1997 • 152 citations

Immunologic Control of HIV-1

2002 • 150 citations

Persistent infection of macaques with simian-human immunodeficiency viruses

1995 • 138 citations

A Nonhuman Primate Model for the Selective Elimination of CD8+ Lymphocytes Using a Mouse-Human Chimeric Monoclonal Antibody

1999 • 131 citations

Potent and synergistic neutralization of human immunodeficiency virus (HIV) type 1 primary isolates by hyperimmune anti-HIV immunoglobulin combined with monoclonal antibodies 2F5 and 2G12

1997 • 119 citations

Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques

2003 • 107 citations

Neutralizing antibodies against HIV – back in the major leagues?

2002 • 86 citations

Potent neutralization of primary human immunodeficiency virus clade C isolates with a synergistic combination of human monoclonal antibodies raised against clade B.

2001 • 53 citations

Deceptive imprinting: a cosmopolitan strategy for complicating vaccination

1998 • 50 citations

Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques

2002 • 49 citations

Additive Effects Characterize the Interaction of Antibodies Involved in Neutralization of the Primary Dualtropic Human Immunodeficiency Virus Type 1 Isolate 89.6

2001 • 48 citations

Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen.

1996 • 47 citations

Postnatal pre‐ and postexposure passive immunization strategies: protection of neonatal macaques against oral simian–human immunodeficiency virus challenge

2002 • 43 citations

DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus

2002 • 34 citations

Short Communication Antibody and Cellular Immune Responses in Breakthrough Infection Subjects after HIV Type 1 Glycoprotein 120 Vaccination

1999 • 27 citations

Heterologous Neutralizing Antibody Induction in a Simian‐Human Immunodeficiency Virus Primate Model: Lack of Original Antigenic Sin

2001 • 14 citations

Deceptive Imprinting: Insights into Mechanisms of Immune Evasion and Vaccine Development

1999 • 13 citations