Core and E antigen synthesis in rodent cells transformed with hepatitis B virus DNA is associated with greater than genome length viral messenger RNAs

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

VIRUS-LIKE PARTICLES IN SERUM OF PATIENTS WITH AUSTRALIA-ANTIGEN-ASSOCIATED HEPATITIS

1970 • 1,003 citations

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

1979 • 992 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene

1976 • 781 citations

DNA Polymerase Associated with Human Hepatitis B Antigen

1973 • 741 citations

The making of strand-specific M13 probes

1982 • 652 citations

Transcriptional control in the production of liver-specific mRNAs

1981 • 593 citations

Hepatitis B virus genes and their expression in E. coli

1979 • 584 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

New Specificities in Australia Antigen Positive Sera Distinct from the Le Bouvier Determinants

1972 • 497 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

Nucleotide sequence of the filamentous bacteriophage M13 DNA genome: comparison with phage fd

1980 • 405 citations

"SPECIAL" CALLS IN GENERAL PRACTICE.

1963 • 394 citations

AVIRULENT CORYNEBACTERIA

1975 • 371 citations

NEW ANTIGEN-ANTIBODY SYSTEM IN AUSTRALIA-ANTIGEN-POSITIVE HEPATITIS

1971 • 353 citations

Hepatitis B surface antigen produced by a human hepatoma cell line

1976 • 323 citations

Nucleotide sequence of a cloned woodchuck hepatitis virus genome: comparison with the hepatitis B virus sequence

1982 • 296 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Hepatitis B virus contains protein attached to the 5′ terminus of its complete DNA strand

1980 • 248 citations

Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line

1980 • 247 citations

Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322

1979 • 239 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

Nucleotide sequence of Xenopus laevis 18S ribosomal RNA inferred from gene sequence

1981 • 210 citations

Multiple polyadenylation sites in a mouse α-amylase gene

1981 • 184 citations

A short primer for sequencing DNA cloned in the single-stranded phage vector M13mp2

1980 • 162 citations

Comparison of viral RNA sequences in adenovirus 2-transformed and lytically infected cells

1975 • 147 citations

Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene.

1982 • 146 citations

Structure of Hepatitis B Dane Particle DNA and Nature of the Endogenous DNA Polymerase Reaction

1977 • 139 citations

The conversion of hepatitis B core antigen synthesized in e coli into e antigen

1981 • 132 citations

The ovalbumin gene family: Structure of the X gene and evolution of duplicated split genes

1980 • 128 citations

Transcription of the hepatitis B surface antigen gene in mouse cells transformed with cloned viral DNA

1982 • 121 citations

Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2

1980 • 95 citations

Visualisation in the Electron Microscope and Size of RNA from Animal Cells

1969 • 94 citations

Integration pattern of hepatitis B virus DNA sequences in human hepatoma cell lines

1981 • 94 citations

Characterization of the steady-state population of messenger RNA and its poly(adenylic acid) segment in mammalian cells

1974 • 81 citations

Hepatitis B Viral DNA Molecules Have Cohesive Ends

1979 • 79 citations

Expression of the hepatitis B virus surface, core and E antigen genes by stable rat and mouse cell lines

1982 • 78 citations

Characterisation of polyoma late mRNA leader sequences by molecular cloning and DNA sequence analysis

1980 • 68 citations

Comparison of nucleotide sequences of large T1 ribonuclease fragments of 18S ribosomal RNA of rat and chicken

1979 • 15 citations