Nucleophilic modification of human complement protein C3: correlation of conformational changes with acquisition of C3b-like functional properties

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

1971 • 8,619 citations

An enzymic method for the trace iodination of immunoglobulins and other proteins

1969 • 1,414 citations

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution.

1977 • 685 citations

[27] Circular dichroism and optical rotatory dispersion of proteins and polypeptides

1973 • 547 citations

Third component of human complement: purification from plasma and physicochemical characterization

1976 • 523 citations

Anaphylatoxins: C3a and C5a

1978 • 502 citations

Human Monocytes: Distinct Receptor Sites for the Third Component of Complement and for Immunoglobulin G

1968 • 492 citations

ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUM

1969 • 430 citations

Molecular Biology and Chemistry of the Alternative Pathway of Complement

1980 • 409 citations

Evidence for presence of an internal thiolester bond in third component of human complement.

1980 • 368 citations

Human alternative complement pathway: membrane-associated sialic acid regulates the competition between B and beta1 H for cell-bound C3b.

1979 • 339 citations

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement.

1980 • 328 citations

Complement dependent immune phagocytosis

1968 • 295 citations

THE REACTION MECHANISM OF ß1C-GLOBULIN (C'3) IN IMMUNE HEMOLYSIS

1966 • 250 citations

THE REACTION MECHANISM OF HUMAN C5 IN IMMUNE HEMOLYSIS

1970 • 196 citations

The Alternative Pathway of Complement Activation

1976 • 180 citations

The binding of human complement component C4 to antibody-antigen aggregates

1980 • 162 citations

Third component of human complement: structural requirements for its function

1980 • 138 citations

Third component of human complement: appearance of a sulfhydryl group following chemical or enzymic inactivation

1980 • 137 citations

Effects of Low Ionic Strength on Immune Hemolysis

1963 • 135 citations

A new function of the activated third component of complement: binding to C5, an essential step for C5 activation.

1978 • 126 citations

Methylamine reaction and denaturation-dependent fragmentation of complement component 3. Comparison with alpha2-macroglobulin.

1980 • 71 citations

The structure and function of the third component of human complement—I. The nature and extent of conformational changes accompanying C3 activation

1981 • 64 citations

Folding pathways of immunoglobulin domains. The folding kinetics of the C.gamma.3 domain of human IgG1

1979 • 33 citations

Hapten-linked conformational equilibria in immunolglobulins XRPC-24 and J-539 observed by chemical relaxation

1978 • 24 citations

The effects of mild reduction on the structure and function of C3.

1980 • 10 citations