Monoamine Oxidase Inhibitors

Some observations upon a new inhibitor of monoamine oxidase in brain tissue

1968 • 1,589 citations

3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists

1957 • 1,233 citations

A sensitive and specific assay for the estimation of monoamine oxidase

1963 • 992 citations

Biogenic Amines and Emotion

1967 • 878 citations

Identification and assay of serotonin in brain.

1956 • 850 citations

Fortschritte der Arzneimittelforschung

1960 • 669 citations

THE SPECTROPHOTOMETRIC DETERMINATION OF AMINE, AMINO ACID AND PEPTIDE WITH 2,4,6- TRINITROBENZENE 1-SULFONIC ACID*

1960 • 484 citations

A rapid microfluorimetric determination of monoamine oxidase

1965 • 406 citations

A Rapid Spectrophotometric Assay of Monoamine Oxidase Based on the Rate of Disappearance of Kynuramine

1960 • 403 citations

Recent Advances in Biological Psychiatry

1968 • 398 citations

Design of Active-Site-Directed Irreversible Enzyme Inhibitors.

1967 • 387 citations

The biochemistry of copper.

1968 • 366 citations

Progress in Brain Research

1963 • 347 citations

HYPERTENSIVE CRISIS DUE TO MONOAMINE-OXIDASE INHIBITORS

1963 • 329 citations

Tyramine oxidase

1928 • 276 citations

Influence of isonicotinic acid hydrazide (INH) and 1-isonicotinyl-2-isopropyl hydrazide (IIH) on bacterial and mammalian enzymes

1952 • 262 citations

In vivo Inhibition of Liver and Brain Monoamine Oxidase by 1-Isonicotinyl-2-Isopropyl Hydrazine.

1952 • 252 citations

STORAGE AND METABOLISM OF CATECHOLAMINES: THE ROLE OF MONOAMINE OXIDASE.

1964 • 232 citations

Multiple Forms of Human Brain Mitochondrial Monoamine Oxidase

1970 • 227 citations

Assay of Serotonin and Related Metabolites, Enzymes, and Drugs

1958 • 219 citations

Pharmacological studies with the serotonin precursor, 5-hydroxytryptophan.

1958 • 209 citations

A clinical and pharmacodynamic evaluation of iproniazid as a psychic energizer.

1957 • 201 citations

Some Neurophysiological Aspects of Serotonin

1954 • 186 citations

AMINE OXIDASES

1955 • 183 citations

Mitochondrial Monoamine Oxidase

1968 • 173 citations

Mitochondrial Monoamine Oxidase

1967 • 153 citations

Physiological Role of Monoamine Oxidase

1958 • 144 citations

Amine oxidases and methods for their study

1970 • 139 citations

A colorimetric micromethod for determination of ammonia; the ammonia content of rat tissues and human plasma

1957 • 130 citations

A simple and sensitive fluorescence assay for monoamine oxidase and diamine oxidase.

1968 • 126 citations

Physiologic and Pharmacologic Considerations of Biogenic Amines in the Nervous System

1968 • 118 citations

Inhibitors of Monoamine Oxidase

1968 • 117 citations

Tricyclic Antidepressants and Monoamine Oxidase Inhibitors

1971 • 111 citations

The mechanism of the irreversible inhibition of rat liver monoamine oxidase by iproniazid (Marsilid)

1957 • 108 citations

Modifications of the pharmacology of reserpine and serotonin by iproniazid.

1957 • 104 citations

Additional evidence for the existence of several forms of mitochondrial monoamine oxidase in the mouse

1968 • 97 citations

DEUTERIUM ISOTOPE EFFECTS IN RELATION TO THE CHEMICAL MECHANISM OF MONOAMINE OXIDASE*

1963 • 95 citations

Amine Oxidase

1966 • 88 citations

Drugs affecting the central nervous system

2023 • 84 citations

Biochemical and pharmacological effects of the monoamine oxidase inhibitors, iproniazid, 1-phenyl-2-hydrazinopropane (JB 516) and 1-phenyl-3-hydrazinobutane (JB 835).

1960 • 82 citations

The prosthetic groups of pig brain mitochondrial monoamine oxidase

1968 • 82 citations

Amine oxidase

1939 • 79 citations

Central Stimulants. Chemistry and Structure-Activity Relationship of Aralkyl Hydrazines

1959 • 76 citations

Brain Chemistry and Mental Disease

1971 • 75 citations

The Purification of Pig Brain Mitochondrial Monoamine Oxidase

1968 • 71 citations

Possible isoenzymes of monoamine oxidase in rat tissues

1968 • 68 citations

Partial Separation of Rat Liver Mitochondrial Amine Oxidases

1963 • 64 citations

Structure-action relationship of β-carbolines as monoamine oxidase inhibitors

1966 • 62 citations

Kinetic studies and effects in vivo of a new monoamine oxidase inhibitor, N[2(ochlorophenoxy)-ethyl]-cyclopropylamine

1968 • 61 citations

STRUCTURE‐ACTIVITY RELATIONS IN THE PARGYLINE SERIES

1963 • 58 citations

2-Substituted Cyclopropylamines. II. Effect of Structure upon Monoamine Oxidase-Inhibitory Activity as Measured in Vivo by Potentiation of Tryptamine Convulsions

1962 • 58 citations

PHARMACOLOGY OF IPRONIAZID AND OTHER AMINE OXIDASE INHIBITORS

1959 • 57 citations

Recent advances in biological psychiatry

1968 • 56 citations

Purification and properties of monoamineoxidase

1963 • 56 citations

Beef mitochondrial monoamine oxidase, a flavin dinucleotide enzyme

1967 • 55 citations

Isoenzymes of human and rat liver monoamine oxidase

1968 • 54 citations

Experimental Study of Specific Final-State Decay Modes Following Photoparticle Reactions in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>16</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math>

1967 • 54 citations

A sensitive assay of monoamine oxidase activity in vitro: application to heart and sympathetic ganglia.

1962 • 53 citations

Inhibition of monoamine oxidase in man by furazolidone

1968 • 53 citations

Multiple Forms of Monoamine Oxidase in the Developing Brain

1969 • 52 citations

The prosthetic groups of animal amine oxidases

1966 • 51 citations

Monoamine oxidase inhibitors

1984 • 51 citations

Synthesis and in Vitro Activity of Some Aryl Diaziridines as Potential Monoamine Oxidase Inhibitors^1a-c

1964 • 50 citations

Structure of the covalently bound flavin of monoamine oxidase

1971 • 48 citations

Amine Oxidases

1962 • 47 citations

Quantum yields and primary processes in the photolysis of HNCO vapor at 2062 Å

1968 • 46 citations

Pharmacological analysis of central nervous action

1962 • 45 citations

Comparative Studies in the Characterization of Monoamine Oxidases.

1963 • 45 citations

A New Inhibitor of Serotonin Metabolism

1959 • 45 citations

Lack of relationship between inhibition of monoamine oxidase and potentiation of hexobarbital hypnosis.

1960 • 44 citations

Oxydation von serotonin und tyramin durch rattenlebermitochondrien

1961 • 43 citations

Über die Wirkung von 2‐Phenylcyclopropylaminen auf die monoamin‐oxydase und andere Enzymsysteme. 18. Mitteilung über Amin‐oxydasen

1960 • 43 citations

ANXIETY AND DEPRESSIVE STATES TREATED WITH ISONICOTINYL HYDRAZIDE (ISONIAZID)

1953 • 43 citations

The treatment of angina pectoris and other muscular pain due to ischemia with iproniazid and isoniazid

1958 • 42 citations

TRANYLCYPROMINE AND CHEESE

1963 • 42 citations

The anti-monoamine oxidase effects of furazolidone.

1967 • 42 citations

STUDIES ON MONOAMINE OXIDASE IN INTACT ANIMALS

1954 • 41 citations

Ganglionic Block and Monoamine Oxidase Inhibitors

1959 • 39 citations

THE INACTIVATION OF AMINE OXIDASE BY ENZYMATIC OXIDATIVE PRODUCTS OF CATECHOL AND ADRENALIN

1942 • 39 citations

N-Methyl-N-2-propynyl-1-indanamine. A Potent Monoamine Oxidase Inhibitor

1966 • 38 citations

Human liver mitochondrial monoamine oxidase. III. Kinetic studies concerning time-dependent inhibitions

1969 • 38 citations

Behavioral and Neuropharmacological Actions of N-Aralkylhydroxylamines and Their O-Methyl Ethers

1965 • 38 citations

Some pharmacological and biochemical properties of γ-morpholino-butyrophenone (NSD 2023), a new monoamine oxidase inhibitor

1968 • 37 citations

Multiple monoamine oxidases in rat liver mitochondria

1970 • 37 citations

Studies on Monoamine Oxidase Inhibitors. I. The Autoxidation of β-Phenylisopropylhydrazine as a Model Reaction for Irreversible Monoamine Oxidase Inhibition

1962 • 36 citations

The labeling in vivo of monoamine oxidase by 14 C-pargyline: a tool for studying the synthesis of the enzyme.

1971 • 35 citations

Studies on Monoamine Oxidase: The Mechanism of Inhibition of Monoamine Oxidase by Iproniazid

1963 • 34 citations

Amine oxidase

1969 • 34 citations

STRUCTURE AND ACTIVITY RELATIONSHIPS OF MONOAMINE OXIDASE INHIBITORS

1959 • 34 citations

Monoamine Oxidase Inhibition by a New Carcinostatic Agent, N-Isopropyl- -(2-Methylhydrazino)-p-Toluamide (MIH)

1965 • 33 citations

Amine Oxidases. XXI. A Rapid Method for the Determination of the Activity of Monoamine Oxidase and Monoamine Oxidase Inhibitors¹

1965 • 33 citations

The inhibition of mitochondrial amine oxidases in vitro by proflavine

1964 • 32 citations

MONOAMINE OXIDASE INHIBITION BY A SERIES OF COMPOUNDS STRUCTURALLY RELATED TO BRETYLIUM AND GUANETHIDINE.

1963 • 32 citations

Selective Depression of Sympathetic Transmission by Intravenous Administration of Iproniazid and Harmine.

1960 • 31 citations

The homogeneity of pig brain mitochondrial monoamine oxidase

1968 • 30 citations

Inhibition of monoamine oxidase by N-(phenoxyethyl)cyclopropylamines. Correlation of inhibition with Hammett constants and partition coefficients

1968 • 30 citations

Multiplicity of mitochondrial monoamine oxidases

1968 • 30 citations

Progress in Drug Research

1961 • 28 citations

Monoamine oxidase inhibiting properties of SU-11,739 in the rat. Comparison with pargyline, tranylcypromine and iproniazid.

1967 • 27 citations

Studies of monoamine oxidases

1968 • 27 citations

Plasma Histaminase Activity in Various Mammalian Species; A Rapid Method of Assay.

1967 • 26 citations

The inhibition of monoamine oxidase by arylalkylhydrazines

1962 • 24 citations

Enzymes as Primary Targets of Drugs

1963 • 24 citations

Inhibition of purified rat liver mitochondrial monoamine oxidase by trans-2-phenyl-cyclopropylamine

1966 • 24 citations

Monoamine Oxidase Inhibitors--I. 1-Alkyl and 1-Aralkyl-2-(picolinoyl and 5-methyl-3-isoxazolylcarbonyl)hydrazines

1960 • 24 citations

Studies on the mechanism of inhibition of monoamine-oxidase by hydrazine derivatives

1964 • 23 citations

INHIBITION OF MONOAMINE OXIDASE BY 2‐METHYL‐3‐PIPERIDINOPYRAZINE

1963 • 22 citations

N-Substituted cyclopropylamines as monoamine oxidase inhibitors. Structure-activity relations. Dopa potentiation in mice and in vitro inhibition of kynuramine oxidation

1968 • 22 citations

COMBINED AMITRIPTYLINE AND PHENELZINE POISONING

1963 • 21 citations

Chemistry and Pharmacology of Monoamine Oxidase Inhibitors: Hydrazine Derivatives

1962 • 21 citations

Nitroglycerin (glyceryl trinitrate) as a monoamine oxidase inhibitor.

1967 • 19 citations

Fluorimetric determination of oxidative enzymes

1969 • 19 citations

The route of administration of some hydrazine compounds as a determinant of brain and liver monoamine oxidase inhibition

1961 • 18 citations

Inhibitors of Monoamine Oxidase IV: 6(or 8)Substituted Tetrahydro-β-carbolines and Their 9-Methyl Analogs

1969 • 18 citations

A STUDY OF HINDERED DIARYLMETHYL RADICALS: II. THE BENZHYDRYL MODEL

1966 • 17 citations

Inhibition of monoamine oxidase action on kynuramine by substrate amines and stereoisomeric α-methyl amines

1965 • 17 citations

Allenic Amines: A New Class of Nonhydrazine MAO Inhibitors

1968 • 17 citations

Monoamine Oxidase Inhibitors

1964 • 17 citations

Inhibitors of Monoamine Oxidase II

1968 • 16 citations

Monoamine oxidase inhibiting properties of AB-15—Comparison with tranylcypromine, nialamide and pargyline

1969 • 16 citations

Some 2,3,6,8-Tetrasubstituted Quinazolone Hydrazides as Monoamine Oxidase Inhibitors

1967 • 16 citations

Selective brain monoamine oxidase inhibition resulting from an interaction between reversible and irreversible inhibitors

1965 • 15 citations

The inhibition of monoamine oxidase by styrylquinoliniums

1967 • 15 citations

Inhibitors of Monoamine Oxidase VI: Effects of Substitution on Inhibitory Activity of 6(or 8)-Substituted β-Carbolines

1970 • 15 citations

Über die Wirkung von symmetrischen 1,2‐Dialkylhydrazinen auf Carbonylverbindungen und Amin‐oxydasen. 16. Mitteilung über Amin‐oxydasen

1958 • 15 citations

Enzyme Inhibitory Activity of 3-(2-Aminobutyl)indole Derivatives

1964 • 15 citations

Synthesis of Azetidines

1971 • 14 citations

Aziridine Derivatives as Potential Monoamine Oxidase Inhibitors¹

1966 • 14 citations

Monoamine Oxidase, Psychoenergizers, and Tranquilizers

1959 • 14 citations

INHIBITION OF AMINE OXIDASE BY METAL IONS AND BY SULPHYDRYL COMPOUNDS

1956 • 14 citations

Intramolecular Interaction between the Hydroxyl Group and the Cyclopropane Ring

1969 • 13 citations

LONG‐TERM ANTIHYPERTENSIVE EFFECT OF PARGYLINE HCL WITH AND WITHOUT DIURETIC SULFONAMIDES*

1963 • 13 citations

2-Phenylcyclobutylamine

1961 • 13 citations

The inhibition of rat liver mitochondrial monoamine oxidase by 2-bromo-2-phenylacetaldehyde

1969 • 12 citations

Inhibitors of Monoamine Oxidase III: 9-Substituted-β-Carbolines

1969 • 12 citations

Further studies on the inhibition of monoamine oxidase by M &amp; B 9302 (clorgyline)—II

1969 • 12 citations

Further properties of multiple forms of mitochondrial monoamine oxidase

1969 • 12 citations

Antihypertensive and monoamine oxidase inhibitory activity of some azacycloaklyl-substituted benzaldehyde hydrazone derivatives

1971 • 12 citations

Heterocyclic mesoionic structures, a novel class of monoamine oxidase inhibitors. I. Arylsydnones

1968 • 11 citations

New Pharmacologic Aspects of β-Diethyl-Aminoethyl 2,2-Diphenylpentanoate

1966 • 11 citations

Synthesis of trans-2-Cyclohexyloxycyclopropylamine and Derivatives

1966 • 11 citations

Synthesis and pharmcological effects of some alkyl-, aryl, and aralkylsydnonimines

1971 • 10 citations

Inhibitors of Monoamine Oxidase V: Effect of Substitution on the Transport of Tetrahydro-β-Carboline Analogs to Mouse Brain

1969 • 10 citations

The effect of diethyltryptamine and its derivatives on monoamine oxidase

1964 • 10 citations

Spectrophotometric Assay of Monoamine Oxidase Using 2, 4, 6-Trinitrobenzene-1-sulfonic Acid

1971 • 9 citations

THE COMPETITIVE INHIBITION OF AMINE OXIDASE WITH SPECIAL REFERENCE TO THE CARCINOID SYNDROME

1965 • 9 citations

Volatile amine oxidase inhibitor from hydrazine derivatives

1964 • 7 citations

The effect of different substrates on the inhibition of rat brain and liver monoamine oxidase by arylalkylhydrazines

1970 • 7 citations

The role of microsomal enzymes in the activation and inactivation of modaline sulfate

1966 • 6 citations

Guanylhydrazones, another class of monoamine oxidase inhibitors

1970 • 6 citations

Monoamine Oxidase Inhibitors. Hydrazine Derivatives

1964 • 6 citations

Substituted quinazolonephenoxyethylhydrazines as monoamine oxidase inhibitors

1970 • 5 citations

Inhibition of Rabbit Liver Mitochondrial Monoamine Oxidase by New Hydrazine Derivatives. II. Probable Prosthetic Groups of the Enzyme, and Their Blocking by the Compound 31037-S or 31087-S

1969 • 5 citations

Monoamine Oxidase Inhibitors--II. Some Amino and Dialkylaminobenzyl Hydrazines and their Acyl Derivatives

1961 • 5 citations

A preliminary study of Lilly 51641.

1966 • 5 citations

Compounds with potential enzyme inhibitory activity. Hydroxylamine analogs of 2-propynylamine

1969 • 4 citations

New reflections on monoamine oxidase inhibition

1963 • 4 citations

A Product of the Chemical Reduction of o-Benzenediacetonitrile

1962 • 4 citations

A short‐acting monoamine oxidase inhibitor, Ro 5‐1025

1965 • 3 citations

Some Derivatives of Phenethanolamine as MAO Inhibitors

1970 • 3 citations

Inability of 4-phenyl-n-butylamine to reverse monoamine oxidase inhibition by tranylcypromine

1964 • 2 citations

Inhibition of Liver-Derived Monoamine Oxidase by Several Isopropyl Hydrazides

1968 • 2 citations

Inhibition of mitochondrial monoamine oxidase by 3,4-dimethoxybenzylhydrazine (vetrazin) and its related compounds

1964 • 1 citations

Notes. 2-Hydroxy-2-phenylethylhydrazine Monoamine Oxidase Inhibitors

1969 • 1 citations