Pituitary Hormones in Brain: Where, How, and Why?

Handbook of Physiology.

1960 • 10,428 citations

Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor

1979 • 1,758 citations

β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland

1977 • 1,426 citations

Common precursor to corticotropins and endorphins

1977 • 1,106 citations

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

1976 • 811 citations

Pain Relief by Electrical Stimulation of the Central Gray Matter in Humans and Its Reversal by Naloxone

1977 • 740 citations

Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies.

1978 • 656 citations

Foot-shock induced stress increases β-endorphin levels in blood but not brain

1977 • 576 citations

Prolactin-Secreting Tumors and Hypogonadism in 22 Men

1978 • 485 citations

Occurrence of somatostatin-like immunoreactivity in some peripheral sympathetic noradrenergic neurons

1977 • 466 citations

beta-endorphin is a potent analgesic agent.

1976 • 465 citations

Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary.

1977 • 451 citations

The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?

1976 • 427 citations

Evidence for two separate opiate peptide neuronal systems

1978 • 413 citations

The permeability of the hypophysis and hypothalamus to vital dyes, with a study of the hypophyseal vascular supply

1936 • 358 citations

alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain.

1978 • 352 citations

Hypothalamic-Pituitary Vasculature: Evidence for Retrograde Blood Flow in the Pituitary Stalk¹

1977 • 345 citations

Adrenocorticotropin in Rat Brain: Immunocytochemical Localization in Cells and Axons

1978 • 340 citations

THE NEUROVASCULAR LINK BETWEEN THE NEUROHYPOPHYSIS AND ADENOHYPOPHYSIS

1946 • 338 citations

Peptides and behavior

1977 • 272 citations

beta-Lipotropin: localization of cells and axons in rat brain by immunocytochemistry.

1977 • 236 citations

Can the Pituitary Secrete Directly to the Brain? (Affirmative Anatomical Evidence)

1978 • 228 citations

Pituitary-Brain Vascular Relations: A New Paradigm

1979 • 225 citations

Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland

1977 • 215 citations

Presence of corticotropin in brain of normal and hypophysectomized rats.

1977 • 203 citations

Analysis of the common precursor to corticotropin and endorphin

1978 • 199 citations

Steps involved in the processing of common precursor forms of adrenocorticotropin and endorphin in cultures of mouse pituitary cells

1978 • 198 citations

Prolactin-Like Immunoreactivity: Localization in Nerve Terminals of Rat Hypothalamus

1977 • 192 citations

New Inventions

1964 • 187 citations

NEUROENDOCRINE EMBRYOLOGY AND THE APUD CONCEPT

1976 • 185 citations

Intravenous Naloxone Administration in Schizophrenia and Affective Illness

1977 • 170 citations

Effects of Naloxone on Schizophrenia: Reduction in Hallucinations in a Subpopulation of Subjects

1978 • 167 citations

Appearance of beta-endorphin-like immunoreactivity in human ventricular cerebrospinal fluid upon analgesic electrical stimulation.

1978 • 161 citations

Localization of α-Melanocyte-Stimulating Hormone in Rat Brain and Pituitary

1978 • 160 citations

Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermedia.

1978 • 157 citations

Brain ACTH and endorphin reduced in rats with monosodium glutamate-induced arcuate nuclear lesions

1979 • 157 citations

Peptides in Neurobiology

2011 • 153 citations

Isolation and characterization of the opioid peptides from rat pituitary: beta-endorphin.

1977 • 151 citations

Andrenocorticotropin and β-lipotropin in the hypothalamus

1979 • 148 citations

Coordinate synthesis of corticotropins and endorphins by mouse pituitary tumor cells.

1978 • 140 citations

Prolactin Binding Sites in the Rat Brain

1978 • 138 citations

Evidence for pituitary-brain transport of a behaviorally potent acth analog

1978 • 136 citations

CORTICOTROPIN-LIKE PEPTIDES IN CENTRAL NERVES AND IN ENDOCRINE CELLS OF GUT AND PANCREAS

1977 • 135 citations

Peptidergic neurons: Facts and trends

1978 • 124 citations

Immunoreactive ACTH in Cerebrospinal Fluid¹

1974 • 121 citations

Somatostatin‐containing neurons in the rat brain: Widespread distribution revealed by immunocytochemistry after pretreatment with pronase

1978 • 120 citations

beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphin.

1978 • 118 citations

β-Endorphin-like immunoreactivity in plasma, pituitaries and hypothalamus of rats following treatment with opiates

1978 • 116 citations

Immunocytochemical evidence that the same neurons in the human infundibular nucleus are stained with anti-endorphins and antisera of other related peptides

1978 • 115 citations

Presence of immunoassayable β-lipotropin in bovine brain and spinal cord: Lack of concordance with ACTH concentrations

1977 • 113 citations

Biosynthesis in vitro of immunoreactive 31,000-dalton corticotropin/β-endorphin-like material by bovine hypothalamus

1979 • 102 citations

The evolution of vertebrate corticotrophin and melanocyte stimulating hormone

1975 • 102 citations

Characterization of pro-opiocortin, a precursor to opioid peptides and corticotropin.

1978 • 102 citations

Distribution and Characterization of a-Melanocyte-Stimulating Hormone in the Rat Brain*

1978 • 97 citations

Biologically Active Pituitary Hormones in the Rat Brain Amygdaloid Nucleus

1978 • 97 citations

Specific Demonstration of the Human Hypophyseal Adrenocortico-Melanotropic (ACTH/MSH) Cell

1974 • 97 citations

On the Presence in Hog Hypothalamus of (β-Corticotropin Releasing Factor,α- and (β-Melanocyte Stimulating Hormones, Adrenocorticotropin, Lysine-Vasopressin and Oxytocin

1962 • 94 citations

β-Endorphin Is Not Detectable in Plasma from Normal Human Subjects

1978 • 93 citations

Presence of corticotropin in limbic system of normal and hypophysectomized rats

1977 • 92 citations

A “Short” Feedback Loop in the Control of ACTH Secretion

1965 • 82 citations

?-lipotropin in brain: Localization in hypothalamic neurons by immunoperoxidase technique

1978 • 81 citations

Electron microscopic immunohistochemical localization of α‐MSH in the rat brain

1977 • 71 citations

Extrahypophysial distribution of corticotropin as a function of brain size.

1978 • 70 citations

Luteinizing Hormone-Releasing Activity in Hypophysial Stalk Blood and Elevation by Dopamine

1969 • 67 citations

Identification of prolactin in cerebrospinal fluid

1974 • 58 citations

Effect of Stress, Adrenocorticotropin or Corticosteroid Treatment, Adrenalectomy, or Hypophysectomy on Hypothalamic Immunoreactive Adrenocorticotropin Concentrations*

1979 • 58 citations

Cerebrospinal Fluid Hormone Concentration in the Evaluation of Pituitary Tumors

1976 • 55 citations

Blood Samples from the Pituitary Stalk of the Rat: Method of Collection and Factors Determining Volume

1966 • 55 citations

Immunohistochemical localization of alpha-melanocyte stimulating hormone (α-MSH) in the human hypothalamus

1978 • 54 citations

Chromatography and Hormonal Activities of Dog Hypothalamus

1962 • 52 citations

The neurohypophyseal capillary bed II. Specializations within median eminence

1978 • 51 citations

Effects of Iontophoretically-Applied Prolactin on Unit Activity of the Rat Brain

1975 • 50 citations

Cerebrospinal Fluid Prolactin: A Reflection of Abnormal Prolactin Secretion in Patients with Pituitary Tumors

1976 • 50 citations

STRUCTURE OF THE VASCULAR CONNECTIONS OF THE HYPOTHALAMO-HYPOPHYSIAL REGION

1964 • 50 citations

Ependymal absorption of luteinizing hormone-releasing hormone injected into the third ventricle of the rat

1975 • 47 citations

Lipotropin: Localization by radioimmunoassay of endorphin precursor in pituitary and brain

1977 • 46 citations

Transport of Thyrotropin-Releasing Hormone from Cerebrospinal Fluid to Hypophysial Portal Blood and the Release of Thyrotropin

1975 • 45 citations

The regional distribution of immunoreactive β-endorphin in the monkey brain

1978 • 42 citations

The analgesic activity of human beta-endorphin in man (1,2,3).

1978 • 40 citations

PROTEIN HORMONES IN CEREBROSPINAL FLUID: EVIDENCE FOR RETROGRADE TRANSPORT OF PROLACTIN FROM THE PITUITARY TO THE BRAIN IN MAN

1978 • 39 citations

Adrenocorticotropic Hormone Biotransformation, Clearance, and Catabolism*

1978 • 39 citations

VASCULAR RESPONSES IN THE PITUITARY STALK¹

1960 • 38 citations

Immunohistochemical localization of β-LPH in the human hypothalamus

1978 • 35 citations

Extrahypophysial distribution of thyrotropin as a function of brain size

1978 • 30 citations

Follicle Stimulating Hormone Releasing Activity in Hypophysial Portal Blood and Elevation by Dopamine

1970 • 19 citations

Dopamine—advances in biochemical psychopharmacology

1979 • 18 citations

beta-endorphin: subjective and objective effects during acute narcotic abstinence in man.

1978 • 12 citations

Transformation of³H-Dopamine During Transport from CSF to Hypophysial Portal Blood¹

1975 • 9 citations

Book Review: Recent Advances in Child Psychopharmacology

1978 • 1 citations