ER Inhibits Proliferation and Invasion of Breast Cancer Cells

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

ERβ: Identification and characterization of a novel human estrogen receptor

1996 • 2,262 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1

1999 • 1,055 citations

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.

1995 • 665 citations

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

1992 • 530 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 526 citations

Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors.

2001 • 476 citations

Estrogen receptor beta--a new dimension in estrogen mechanism of action

1999 • 434 citations

The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions

1999 • 369 citations

Estrogen receptor β acts as a dominant regulator of estrogen signaling

2000 • 366 citations

Estrogen receptors α and β in the rodent mammary gland

2000 • 357 citations

Selective loss of estrogen receptor beta in malignant human colon.

2000 • 313 citations

Inhibitory Function of p21 ^Cip1/WAF1 in Differentiation of Primary Mouse Keratinocytes Independent of Cell Cycle Control

1998 • 285 citations

Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis.

1998 • 283 citations

Estrogen Receptor β Is Coexpressed with ERα and PR and Associated with Nodal Status, Grade, and Proliferation Rate in Breast Cancer

2000 • 282 citations

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens

1995 • 273 citations

Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras¹

1998 • 267 citations

Growth Regulation of Estrogen Receptor-Negative Breast Cancer Cells Transfected With Complementary DNAs for Estrogen Receptor

1992 • 263 citations

Differentiation state and invasiveness of human breast cancer cell lines

1994 • 260 citations

Induction of hTERT Expression and Telomerase Activity by Estrogens in Human Ovary Epithelium Cells

2000 • 255 citations

Increased expression of estrogen receptor beta mRNA in tamoxifen-resistant breast cancer patients.

1999 • 240 citations

Down-regulation of p21 ^WAF1/CIP1 or p27 ^Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells

2000 • 227 citations

The Estrogen Receptor -Isoform (ER ) of the Human Estrogen Receptor Modulates ER Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens

1999 • 223 citations

Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis.

1998 • 209 citations

Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells.

1992 • 176 citations

Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis

1993 • 159 citations

Functional Differences between the Amino-Terminal Domains of Estrogen Receptors α and β

2000 • 155 citations

Construction of Cell Lines that Express High Levels of the Human Estrogen Receptor and Are Killed by Estrogens

1990 • 152 citations

Absence of estrogen receptor-β expression in metastatic ovarian cancer

2000 • 149 citations

Estrogen hits the surface

1999 • 149 citations

Quantitative analysis of estrogen receptor-? mRNA and its variants in human breast cancers

2000 • 127 citations

Clinical value of the wild-type estrogen receptor β expression in breast cancer

2001 • 124 citations

p21Waf1/Cip1 Is an Assembly Factor Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Proliferation

2000 • 108 citations

The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions

1999 • 105 citations

The influence of maternal diet on breast cancer risk among female offspring

1999 • 66 citations

Transcription Activation by the Human Estrogen Receptor Subtype (ER ) Studied with ER and ER Receptor Chimeras

1998 • 66 citations

Adenovirus-Mediated Delivery of a Dominant Negative Estrogen Receptor Gene Abrogates Estrogen-Stimulated Gene Expression and Breast Cancer Cell Proliferation

1999 • 62 citations

Progesterone Induces Focal Adhesion in Breast Cancer Cells MDA-MB-231 Transfected with Progesterone Receptor Complementary DNA

2000 • 61 citations

Human estrogen receptor beta-specific monoclonal antibodies: characterization and use in studies of estrogen receptor beta protein expression in reproductive tissues

2001 • 60 citations

Effects of epidermal growth factor, estrogen, and progestin on DNA synthesis in mammary cells in vivo are determined by the developmental state of the gland

1993 • 57 citations

Promotion of estrogen-induced mammary gland carcinogenesis by androgen in the male Noble rat: probable mediation by steroid receptors

1998 • 55 citations

Endocrine Therapy of Breast Cancer

1975 • 55 citations

Paradoxical regulation of estrogen-dependent growth factor gene expression in estrogen receptor (ER)-negative human breast cancer cells stably expressing ER

1994 • 54 citations

Association of in vitro invasiveness and gene expression of estrogen receptor, progesterone receptor, pS2 and plasminogen activator inhibitor‐1 in human breast cancer cell lines

1999 • 53 citations

Differentiation and breast cancer.

1997 • 51 citations

Induction of Estrogen-Regulated Genes Differs in Immortal and Tumorigenic Human Mammary Epithelial Cells Expressing a Recombinant Estrogen Receptor

1991 • 47 citations

Expression of human estrogen receptor using an efficient adenoviral gene delivery system is able to restore hormone-dependent features to estrogen receptor-negative breast carcinoma cells

1999 • 42 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor

1998 • 33 citations

Hormonal regulation of cathepsin D following transfection of the estrogen or progesterone receptor into three sex steroid hormone resistant cancer cell lines

1991 • 32 citations

Phylogenetic Analyses Reveal Ancient Duplication of Estrogen Receptor Isoforms

1999 • 30 citations

Relationship between tumorigenicity, in vitro invasiveness, and plasminogen activator production of human breast cell lines

1990 • 29 citations

Rapid Non-genomic Vasodilator Actions of Oestrogens and Sex Steroids

2000 • 25 citations

Regulation of Metallothionein II Messenger Ribonucleic Acid Measures Exogenous Estrogen Receptor-β Activity in SAOS-2 and LNCaPLN3 Cells

2001 • 22 citations

Adenovirus-Mediated Delivery of a Dominant Negative Estrogen Receptor Gene Abrogates Estrogen-Stimulated Gene Expression and Breast Cancer Cell Proliferation

1999 • 19 citations

Progesterone Induces Focal Adhesion in Breast Cancer Cells MDA-MB-231 Transfected with Progesterone Receptor Complementary DNA

2000 • 19 citations

Regulation of Metallothionein II Messenger Ribonucleic Acid Measures Exogenous Estrogen Receptor- Activity in SAOS-2 and LNCaPLN3 Cells

2001 • 8 citations