Expression of c‐met proto‐oncogene in COS cells induces the signal transducing high‐affinity receptor for hepatocyte growth factor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats

1984 • 1,153 citations

Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.

1991 • 698 citations

Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.

1991 • 663 citations

Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures.

1986 • 588 citations

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

1987 • 567 citations

Purification and subunit structure of hepatocyte growth factor from rat platelets

1987 • 557 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Structure and function of hepatocyte growth factor

1991 • 307 citations

Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction.

1989 • 289 citations

Hepatocyte growth factor is a potent mitogen for cultured rabbit renal tubular epithelial cells

1991 • 259 citations

Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor

1991 • 217 citations

[39] Vectors used for expression in mammalian cells

1990 • 188 citations

Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases.

1988 • 183 citations

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing.

1991 • 139 citations

Hepatocyte growth factor: Molecular structure and implications for a central role in liver regeneration

1991 • 130 citations

Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable

1991 • 129 citations

Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis

1991 • 123 citations

Acquisition of a beta-adrenergic response by adult rat hepatocytes during primary culture.

1983 • 117 citations

Scatter factor from human embryonic lung fibroblasts is probably identical to hepatocyte growth factor

1991 • 81 citations