Factors affecting the susceptibility of the mouse pituitary gland to CD8 T‐cell‐mediated autoimmunity

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

T Cell Anergy

2003 • 1,418 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

2001 • 1,043 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

2000 • 723 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

2003 • 713 citations

A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis

2001 • 650 citations

Myelin Antigen-Specific CD8+ T Cells Are Encephalitogenic and Produce Severe Disease in C57BL/6 Mice

2001 • 437 citations

Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice

1997 • 359 citations

Major Histocompatibility Complex Class I–restricted Cross-presentation Is Biased towards High Dose Antigens and Those Released during Cellular Destruction

1998 • 323 citations

Endocrinological Disorders and Celiac Disease

2002 • 312 citations

Cell-Associated Ovalbumin Is Cross-Presented Much More Efficiently than Soluble Ovalbumin In Vivo

2001 • 260 citations

CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose

1999 • 245 citations

Inherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6

1976 • 241 citations

CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

2002 • 241 citations

Regulatory CD4+CD25+ T Cells Restrict Memory CD8+ T Cell Responses

2002 • 209 citations

Autoreactive CD8 T Cells in Organ-Specific Autoimmunity

2002 • 204 citations

Promiscuous gene expression and central T-cell tolerance: more than meets the eye

2002 • 198 citations

Positive and Negative Selection in Transgenic Mice Expressing a T-Cell Receptor Specific for Influenza Nucleoprotein and Endogenous Superantigen

1993 • 181 citations

Antigen Concentration and Precursor Frequency Determine the Rate of CD8+ T Cell Tolerance to Peripherally Expressed Antigens

1999 • 174 citations

CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice

1998 • 159 citations

Identification of a CD8 T Cell That Can Independently Mediate Autoimmune Diabetes Development in the Complete Absence of CD4 T Cell Helper Functions

2000 • 148 citations

Anterior Pituitary Cell Population Control: Basal Cell Turnover and the Effects of Adrenalectomy and Dexamethasone Treatment

1998 • 135 citations

Expression of two T cell receptor α chains on the surface of normal murine T cells

1995 • 131 citations

Regulation of the pituitary somatotroph cell by GHRH and its receptor.

2000 • 117 citations

Identification of the 49-kDa Autoantigen Associated with Lymphocytic Hypophysitis as α-Enolase

2002 • 114 citations

Autosomal Dominant Growth Hormone Deficiency Disrupts Secretory Vesiclesin Vitroandin Vivoin Transgenic Mice

2003 • 114 citations

Detection of autoantibodies against the pituitary-specific proteins in patients with lymphocytic hypophysitis

2002 • 99 citations

Physiological implications of pituitary trophic activity

2002 • 90 citations

Growth hormone (GH) secretion in the dwarf rat: release, clearance and responsiveness to GH-releasing factor and somatostatin

1990 • 78 citations

Identification of the 49-kDa Autoantigen Associated with Lymphocytic Hypophysitis as -Enolase

2002 • 66 citations

A Secreted Fluorescent Reporter Targeted to Pituitary Growth Hormone Cells in Transgenic Mice

2000 • 65 citations

Autoimmunity caused by ignorant CD8+ T cells is transient and depends on avidity.

1995 • 60 citations

Functional recognition of in vivo processed self antigen

1994 • 53 citations

Autoimmune endocrine disease

2002 • 37 citations

Triggering a Second T Cell Receptor on Diabetogenic T Cells Can Prevent Induction of Diabetes

1999 • 27 citations

Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen

1999 • 22 citations

Activation of CD8 T Cells by Antigen Expressed in the Pituitary Gland

2002 • 22 citations

Autoimmune Polyglandular Endocrinopathy and Anterior Hypophysitis in a 14 Year-Old Girt Presenting with Delayed Puberty

2001 • 7 citations