Comparison of the proteolytic susceptibilities of homologous L‐amino acid, D‐amino acid, and N‐substituted glycine peptide and peptoid oligomers

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

A new type of synthetic peptide library for identifying ligand-binding activity

1991 • 1,769 citations

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

1991 • 1,319 citations

Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis

1992 • 1,190 citations

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

1994 • 1,130 citations

Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

1994 • 1,126 citations

General method for rapid synthesis of multicomponent peptide mixtures

1991 • 1,122 citations

Peptoids: a modular approach to drug discovery.

1992 • 918 citations

Structural basis of the activation and action of trypsin

1978 • 669 citations

On the active site of proteases. III. Mapping the active site of papain; specific peptide inhibitors of papain

1968 • 400 citations

Discovery of Nanomolar Ligands for 7-Transmembrane G-Protein-Coupled Receptors from a Diverse N-(Substituted)glycine Peptoid Library

1994 • 356 citations

Proteolytic studies of homologous peptide and N-substituted glycine peptoid oligomers

1994 • 297 citations

Refined crystal structure of the potato inhibitor complex of carboxypeptidase A at 2.5 Å resolution

1982 • 260 citations

Fluorimetric determination of secondary amino acids by 7-fluoro-4-nitrobenzo-2-oxa-1,3-diazole

1981 • 206 citations

The influence of peptide structure on transport across Caco-2 cells. II. Peptide bond modification which results in improved permeability.

1992 • 201 citations

The Mechanism of the Catalytic Action of Pepsin and Related Acid Proteinases

1976 • 159 citations

Mechanisms of Protease Action

1989 • 157 citations

Conformational specificity of chymotrypsin toward proline-containing substrates

1984 • 157 citations

On the size of the active site in proteases II. Carboxypeptidase-A

1967 • 152 citations

Dependence of the kinetic parameters for elastase-catalyzed amide hydrolysis on the length of peptide substrates

1973 • 110 citations

Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin A.alpha., and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates

1984 • 91 citations

Further studies on the reaction of amines and proteins with 4-fluoro-7-nitrobenzo-2-oxa-1,3-diazole

1985 • 89 citations

Subsite Specificity of Porcine Pepsin

1977 • 87 citations

Design, construction and application of a fully automated equimolar peptide mixture synthesizer

1992 • 64 citations

Recent advances in the generation of chemical diversity libraries

1994 • 60 citations

Extended binding inhibitors of chymotrypsin that interact with leaving group subsites S1'-S3'

1987 • 60 citations

The active centers of Streptomyces griseus protease 3, α-chymotrypsin, and elastase: enzyme-substrate interactions close to the scissile bond

1976 • 46 citations

Studies on the Extended Active Site of Papain

1974 • 36 citations

Investigation of the Substrate-Binding Site of Trypsin by the Aid of Tripeptidyl-p-nitroanilide Substrates

2005 • 32 citations

Enzyme Handbook 1

1990 • 28 citations

Systematic screening for bioactive peptides.

1991 • 15 citations

Pathologie respiratoire du Sommeil du Nourrisson et de L'enfant (respiratory pathology of sleep in infants and children), edited by C. Gaultier. Part of the “Cliniques de Pediatrie” series. Paris: Editions Vigot, 1989

1989 • 12 citations

Absorption of light and ultraviolet radiation : fluorescence and phosphorescence emission : an introduction with experiments

1973 • 9 citations

High-performance liquid chromatographic method for the determination of prolyl peptides in urine

1991 • 9 citations