Structure of the DNA-Bound T-Box Domain of Human TBX3, a Transcription Factor Responsible for Ulnar-Mammary Syndrome

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht

1999 • 1,932 citations

SETOR: Hardware-lighted three-dimensional solid model representations of macromolecules

1993 • 1,295 citations

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

1997 • 1,066 citations

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

2001 • 1,062 citations

Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice

2001 • 996 citations

TBX1 Is Responsible for Cardiovascular Defects in Velo-Cardio-Facial/DiGeorge Syndrome

2001 • 963 citations

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

1997 • 909 citations

Three-dimensional structure of the Stat3β homodimer bound to DNA

1998 • 769 citations

The Immunoglobulin Fold

1994 • 679 citations

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

1997 • 536 citations

A Pituitary Cell-Restricted T Box Factor, Tpit, Activates POMC Transcription in Cooperation with Pitx Homeoproteins

2001 • 533 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 406 citations

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers

2000 • 367 citations

Different TBX5 interactions in heart and limb defined by Holt–Oram syndrome mutations

1999 • 362 citations

Crystallographic structure of the T domain–DNA complex of the Brachyury transcription factor

1997 • 327 citations

A-form Conformational Motifs in Ligand-bound DNA Structures

2000 • 325 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 308 citations

The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity

1999 • 293 citations

The T protein encoded by Brachyury is a tissue-specific transcription factor.

1995 • 287 citations

Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds

1999 • 264 citations

T-box genes: what they do and how they do it

1999 • 241 citations

Tbx5 and the Retinotectum Projection

2000 • 234 citations

Tbx5 is essential for heart development

1999 • 219 citations

Evolution of Mouse T-box Genes by Tandem Duplication and Cluster Dispersion

1996 • 189 citations

Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm

1998 • 176 citations

DNA-binding by Ig-fold proteins.

2001 • 172 citations

Brachyury-Related Transcription Factor Tbx2 and Repression of the Melanocyte-Specific TRP-1 Promoter

1998 • 171 citations

The Spectrum of Mutations in TBX3: Genotype/Phenotype Relationship in Ulnar-Mammary Syndrome

1999 • 169 citations

The Assessment of the Geometry of Dinucleotide Steps in Double-Helical DNA; a New Local Calculation Scheme

1995 • 164 citations

The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element

1998 • 141 citations

Bix4 is activated directly by VegT and mediates endoderm formation in Xenopus development

1999 • 130 citations

Kinetic Studies of Fos·Jun·DNA Complex Formation: DNA Binding Prior to Dimerization

2000 • 112 citations

Differential DNA binding and transcription modulation by three T-box proteins, T, TBX1 and TBX2

2000 • 87 citations

Phylogenetic Analysis of T-Box Genes Demonstrates the Importance of Amphioxus for Understanding Evolution of the Vertebrate Genome

2000 • 70 citations

T-box genes and the formation of vertebrate forelimb- and hindlimb specific pattern

1999 • 39 citations

The T transcription factor functions as a dimer and exhibits a common human polymorphism Gly‐177‐Asp in the conserved DNA‐binding domain

1997 • 29 citations