Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Cancer Statistics, 2003

2003 • 3,302 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

The development of androgen-independent prostate cancer

2001 • 2,285 citations

Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer.

2001 • 755 citations

Molecular genetics of prostate cancer

2000 • 723 citations

Primary Renal Neoplasms with the ASPL-TFE3 Gene Fusion of Alveolar Soft Part Sarcoma

2001 • 605 citations

A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy.

2001 • 603 citations

Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease.

2002 • 519 citations

Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.

2001 • 501 citations

The program of androgen-responsive genes in neoplastic prostate epithelium

2002 • 473 citations

Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis

2001 • 471 citations

Prostate-Specific–Antigen Testing for Early Diagnosis of Prostate Cancer

2001 • 413 citations

Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells.

2002 • 395 citations

Hormone Therapy Failure in Human Prostate Cancer: Analysis by Complementary DNA and Tissue Microarrays

1999 • 356 citations

Interleukin-6 and prostate cancer progression

2001 • 262 citations

Functional characterization of mutant androgen receptors from androgen-independent prostate cancer.

1997 • 225 citations

Transcriptional programs activated by exposure of human prostate cancer cells to androgen

2002 • 192 citations

Squalene epoxidase as hypocholesterolemic drug target revisited

2002 • 183 citations

Dysregulated expression of androgen-responsive and nonresponsive genes in the androgen-independent prostate cancer xenograft model CWR22-R1.

2000 • 154 citations

ANDROGEN RECEPTOR GENE AMPLIFICATION AT PRIMARY PROGRESSION PREDICTS RESPONSE TO COMBINED ANDROGEN BLOCKADE AS SECOND LINE THERAPY FOR ADVANCED PROSTATE CANCER

2000 • 153 citations

Clinical and Pathobiological Effects of Neoadjuvant Total Androgen Ablation Therapy on Clinically Localized Prostatic Adenocarcinoma

1994 • 134 citations

Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling

2001 • 125 citations

Differentially Expressed Genes in Two LNCaP Prostate Cancer Cell Lines Reflecting Changes during Prostate Cancer Progression

2000 • 113 citations

Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes

2001 • 112 citations

Role of androgen in prostate growth and regression: Stromal-epithelial interaction

1996 • 72 citations

Androgens, androgen receptors, antiandrogens and the treatment of prostate cancer.

1997 • 50 citations

The clinical and biological study of androgen independent prostate cancer (AI PCa).

1994 • 30 citations

Androgen signal transduction and prostatic carcinoma

1994 • 28 citations

Gene Expression Profiling of the Human Prostate Androgen Response Program

2002 • 8 citations