Dynamic Properties of an Inositol 1,4,5-Trisphosphate– and Thapsigargin-insensitive Calcium Pool in Mammalian Cell Lines

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Calcium signaling

1995 • 1,905 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

1991 • 1,282 citations

Molecular and cellular physiology of intracellular calcium stores

1994 • 1,132 citations

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

1992 • 920 citations

Mitochondrial calcium transport: physiological and pathological relevance

1994 • 702 citations

Characterization of ionomycin as a calcium ionophore.

1978 • 535 citations

Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons

1994 • 494 citations

The elemental principles of calcium signaling

1995 • 455 citations

cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump

1989 • 412 citations

Receptor-activated Ca2+ influx: how many mechanisms for how many channels?

1994 • 403 citations

Transfected Aequorin in the Measurement of Cytosolic Ca2+ Concentration ([Ca2+]c)

1995 • 361 citations

Dominant Role of Mitochondria in Clearance of Large Ca2+ Loads from Rat Adrenal Chromaffin Cells

1996 • 352 citations

A Reevaluation of the Role of Mitochondria in Neuronal Ca²⁺ Homeostasis

1996 • 347 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Mitochondrial Ca2+ homeostasis in intact cells.

1994 • 320 citations

Ryanodine receptors: how many, where and why?

1993 • 310 citations

Neuronal Ca2+ stores: activation and function

1995 • 288 citations

A GTP-dependent step in the activation mechanism of capacitative calcium influx.

1993 • 283 citations

MITOCHONDRIA AND THE CONTROL OF INTRACELLULAR CALCIUM

1978 • 278 citations

Overexpression of Calreticulin Increases Intracellular Ca2+ Storage and Decreases Store-operated Ca2+ Influx

1996 • 266 citations

An FCCP-sensitive Ca2+ store in bullfrog sympathetic neurons and its participation in stimulus-evoked changes in [Ca2+]i

1994 • 262 citations

Expression of a Ryanodine Receptor-Ca ²⁺ Channel that is Regulated by TGF-β

1992 • 247 citations

Coupling between intracellular Ca2+ stores and the Ca2+ permeability of the plasma membrane. Comparison of the effects of thapsigargin, 2,5-di-(tert-butyl)-1,4-hydroquinone, and cyclopiazonic acid in rat thymic lymphocytes.

1991 • 243 citations

Identification of intracellular calcium pools. Selective modification by thapsigargin

1991 • 238 citations

Structural and functional aspects of calcium homeostasis in eukaryotic cells

1990 • 217 citations

A sarco/endoplasmic reticulum Ca(2+)-ATPase 3-type Ca2+ pump is expressed in platelets, in lymphoid cells, and in mast cells.

1994 • 209 citations

Overexpression of calreticulin increases the Ca2+ capacity of rapidly exchanging Ca2+ stores and reveals aspects of their lumenal microenvironment and function.

1995 • 191 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

A Role for Calcium Influx in the Regulation of Mitochondrial Calcium in Endothelial Cells

1996 • 183 citations

Inositol 1,4,5-trisphosphate receptor

1993 • 178 citations

The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway

1996 • 175 citations

Intracellular Ca2+ pools in PC12 cells. Three intracellular pools are distinguished by their turnover and mechanisms of Ca2+ accumulation, storage, and release.

1991 • 171 citations

Intracellular Ca2+ storage organelles in non-muscle cells: Heterogeneity and functional assignment

1990 • 160 citations

Endoplasmic reticulum: a dynamic patchwork of specialized subregions.

1992 • 154 citations

Intracellular Ca2+ pools in PC12 cells. A unique, rapidly exchanging pool is sensitive to both inositol 1,4,5-trisphosphate and caffeine-ryanodine.

1991 • 123 citations

Calcium sequestration in the golgi apparatus of cultured mammalian cells revealed by laser scanning confocal microscopy and ion microscopy

1991 • 119 citations

The rat platelet 97-kDa Ca2+ATPase isoform is the sarcoendoplasmic reticulum Ca2+ATPase 3 protein.

1994 • 109 citations

Mitochondria and other calcium buffers of squid axon studied in situ.

1978 • 95 citations

Immunocytochemistry of calciosomes in liver and pancreas.

1988 • 93 citations

Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells

1990 • 80 citations

Calcium waves

1993 • 76 citations

Dependence of cytosolic calcium in differentiating rat pheochromocytoma cells on calcium channels and intracellular stores.

1991 • 68 citations

Effect of membrane potential on divalent cation transport catalyzed by the “electroneutral” ionophores A23187 and ionomycin

1989 • 66 citations

Functional identification and quantitation of three intracellular calcium pools in GH4C1 cells: Evidence that the caffeine-responsive pool is coupled to a thapsigargin-resistant, ATP-dependent process

1993 • 59 citations

Ca2+ transport and Ca2+-dependent ATP hydrolysis by Golgi vesicles from lactating rat mammary glands

1985 • 58 citations

Functional properties of intracellular calcium-release channels

1995 • 54 citations

High resolution ultrastructural mapping of total calcium: electron spectroscopic imaging/electron energy loss spectroscopy analysis of a physically/chemically processed nerve-muscle preparation.

1996 • 52 citations

Association of cytoplasmic free Ca²⁺ gradients with subcellular organelles

1992 • 49 citations

Thyrotropin-releasing hormone induces opposite effects on Ca2+ channel currents in pituitary cells by two pathways.

1991 • 46 citations

The Endoplasmic Reticulum in PC12 Cells

1996 • 46 citations

Thapsigargin-sensitive Ca2+-ATPases account for Ca2+ uptake to inositol 1,4,5-trisphosphate-sensitive and caffeine-sensitive Ca2+ stores in adrenal chromaffin cells

1995 • 44 citations

Intracellular Ca2+ stores of rat cerebellum: heterogeneity within and distinction from endoplasmic reticulum

1993 • 42 citations

The bulk of Ca²⁺ released to the myoplasm is free in the sarcoplasmic reticulum and does not unbind from calsequestrin

1991 • 39 citations

A Plasma Membrane-Type Ca2+-ATPase of 120 Kilodaltons on the Endoplasmic Reticulum from Carrot (Daucus carota) Cells (Properties of the Phosphorylated Intermediate)

1993 • 38 citations

Caffeine-stimulated Ca2+ release from the intracellular stores of hepatocytes is not mediated by ryanodine receptors

1993 • 37 citations

Intracellular Ca²⁺ stores of T lymphocytes: Changes induced by in vitro and in vivo activation

1994 • 35 citations

A caffeine- and ryanodine-sensitive intracellular Ca2+ store can act as a Ca2+ source and a Ca2+ sink in PC12 cells

1994 • 33 citations

Ammonium ions mobilize calcium from an internal pool which is insensitive to TRH and ionomycin in bovine anterior pituitary cells

1991 • 31 citations

Unidirectional interaction between two intracellular calcium stores in rat phaeochromocytoma (PC12) cells.

1993 • 28 citations

Direct Involvement of Intracellular Ca2+ Transport ATPase in the Development of Thapsigargin Resistance by Chinese Hamster Lung Fibroblasts

1995 • 24 citations

Calcium pools in Ehrlich carcinoma cells. A major, high affinity Ca2+ pool is sensitive to both inositol 1,4,5-trisphosphate and thapsigargin

1995 • 19 citations

Stimulation of single L-type calcium channels in rat pituitary GH3 cells by thyrotropin-releasing hormone.

1995 • 16 citations

Peroxisome biogenesis

1989 • 16 citations

Biochemical and functional heterogeneity of rat cerebrum microsomal membranes in relation to SERCA Ca2+-ATPases and Ca2+ release channels

1996 • 12 citations

A plasma membrane-type Ca[sup 2+]-ATPase of 120 kilodaltons on the endoplasmic reticulum from carrot (Daucus carota) cells

1993 • 12 citations

Ca2+ sparks a wave of excitement

1994 • 12 citations

Visualization of Golgia apparatus as an intracellular calcium store by laser scanning confocal microscope

1995 • 5 citations