Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo

Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus

2003 • 5,611 citations

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

2000 • 2,700 citations

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

1997 • 1,774 citations

Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene

1998 • 1,763 citations

Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer

2003 • 1,572 citations

TGF-β signaling: positive and negative effects on tumorigenesis

2002 • 830 citations

Matrix metalloproteinases in tumor invasion and metastasis

2000 • 820 citations

Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis

2004 • 463 citations

Matrix Metalloproteinases in Human Melanoma

2000 • 414 citations

GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor

2004 • 252 citations

Negative regulation of transforming growth factor-β (TGF-β) signaling by WW domain-containing protein 1 (WWP1)

2004 • 197 citations

Amelioration of Radiation-induced Fibrosis

2004 • 192 citations

Mammalian transforming growth factor-βs: Smad signaling and physio-pathological roles

2003 • 177 citations

Disruption of Basal JNK Activity Differentially Affects Key Fibroblast Functions Important for Wound Healing

2003 • 119 citations

Smad7: a new key player in TGF-β-associated disease

2002 • 58 citations

TGF-β signaling in cancer — a double-edged sword

2001 • 57 citations

The electrical resistance breakdown assay determines the role of proteinases in tumor cell invasion

2002 • 42 citations