Immunopharmacology of 5-(3,3-dIMETHYL-1-triazeno)-imidazole-4-carboxamide (DTIC) (DTIC)

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

Immunity to Methylcholanthrene-Induced Sarcomas

1957 • 1,241 citations

HETEROTRANSPLANTATION OF A HUMAN MALIGNANT TUMOUR TO “NUDE” MICE

1969 • 700 citations

Demonstration of cell‐mediated immunity to human neoplasms of various histological types

1971 • 673 citations

Tumor Antigens

1966 • 323 citations

Heterotransplantation of Human Malignant Tumors in “Nude” Thymusless Mice. II. Malignant Tumors Induced by Injection of Cell Cultures Derived From Human Solid Tumors 2

1974 • 238 citations

Quantitative Studies of <italic>In Vitro</italic> Transformation by Chemical Carcinogens

1969 • 197 citations

Immunological responses of 'nude' mice.

1971 • 176 citations

Passive immunity in mice against C57BL leukosis E.L. 4 by means of iso-immune serum.

1956 • 163 citations

Tumor-specific transplantation antigens: G. H. A. Clowes memorial lecture.

1968 • 132 citations

Detection of Antigenic Differences in Isologous Host-Tumor Systems by Pretreatment with Heavily Irradiated Tumor Cells

1960 • 130 citations

Mutations and decreases in density of transforming DNA produced by derivatives of the carcinogens 2-acetyl-aminofluorene and N-methyl-4-aminoazobenzene.

1968 • 118 citations

N-demethylation the antineoplastic agent4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide by rats and man.

1970 • 98 citations

Demonstration of host resistance against isotransplantation of lymphomas induced by the Gross agent.

1962 • 88 citations

Modification of tumor regression by immunologic means.

1969 • 79 citations

Antigenic changes of L1210 leukemia in mice treated with 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide.

1972 • 71 citations

Antigenicity of L1210 leukemic sublines induced by drugs.

1972 • 66 citations

Incorporation of iododeoxyuridine-125-I into the DNA of L1210 leukemia cells during tumor development.

1970 • 52 citations

Preliminary clinical trial and the physiologic disposition of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide in man.

1969 • 51 citations

Cellular immune response to a drug-treated L5178Y lymphoma subline

1974 • 49 citations

Imidazole carboxamide therapy in advanced malignant melanoma

1971 • 48 citations

Imidazoles. II. 5(or 4)-(Monosubstituted Triazeno)imidazole-4(or 5)-carboxamides¹

1966 • 45 citations

Studies of the mechanism of action of the antitumor agent 5(4)-(3,3-dimethyl-1-triazeno) imidazole-4(5)-carboxamide in Bacillus subtilis

1970 • 42 citations

Effect of imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno) on immunity in patients with malignant melanoma.

1974 • 39 citations

Some Pharmacokinetic Aspects of 5-(Dimethyltriazeno)-imidazole-4-carboxamide in the Dog

1968 • 37 citations

4 (or 5)-diazoimidazole-5 (or 4)-carboxamide and related triazenoimidazoles as antibacterial agents: Their effects on nucleic acid metabolism of Escherichia coli B

1969 • 34 citations

Clinical Evaluation of 5-(3,3-Dimethyl-1-Triazeno) Imidazole-4-Carboxamide in Malignant Melanoma and Other Neoplasms: Comparison of Twice-weekly and Daily Administration Schedules

1971 • 30 citations

Brief Communication: Increased Immunogenicity of Two Lymphoma Lines After Drug Treatment of Athymic (Nude) Mice

1975 • 30 citations

Carcinogenicity of the Antineoplastic Agent, 5-(3,3-Dimethyl-1-triazeno)-imidazole- 4-carboxamide, and Its Metabolites in Rats<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1975 • 29 citations

Triple combination chemotherapy of disseminated melanoma

1972 • 29 citations

Comparative effects of the antitumor agents 5-(Dimethyltriazeno)-imidazole-4-carboxamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on cell cycle of L1210 leukemia cells in vivo.

1970 • 27 citations

Antigenic differences between leukemia L1210 and a subline resistant to methylglyoxal-bis(guanylhydrazone).

1972 • 26 citations

Adoptive immunotherapy in BALB-c times DBA-2 Cr F1 mice bearing an immunogenic subline of L1210 leukemia.

1974 • 25 citations

Intra-arterial therapy of melanoma with dimethyl triazeno imidazole carboxamide (NSC-45388)

1971 • 24 citations

Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugs.

1975 • 23 citations

Role of 4-diazoimidazole-5-carboxamide in the action of the antitumor agent 5(4)-(3,3-dimethyl-1-triazeno) imidazole-4-(5)carboxa-mide in Bacillus subtilis

1972 • 18 citations

Immune inhibition of allogeneic lymphoma cells in the peritoneal cavity of mice.

1975 • 15 citations

Brief Communication: Antigenic Changes Associated With Resistance to Methotrexate and 6-Mercaptopurine in L1210 Ascites Lymphoma 2

1974 • 8 citations