Application of a fluorogenic substrate in the assay of proteolytic activity and in the discovery of a potent inhibitor of Candida albicans aspartic proteinase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Novel Fluorogenic Substrates for Assaying Retroviral Proteases by Resonance Energy Transfer

1990 • 589 citations

The slow-binding and slow, tight-binding inhibition of enzyme-catalysed reactions

1982 • 488 citations

Genetic evidence for role of extracellular proteinase in virulence of Candida albicans

1985 • 259 citations

Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa

1988 • 228 citations

Virulence For Mice Of A Proteinase-Secreting Strain Of Candida Albicans And A Proteinase-Deficient Mutant

1983 • 204 citations

Scanning electron microscopy of epidermal adherence and cavitation in murine candidiasis: a role for Candida acid proteinase

1988 • 189 citations

Properties of a purified proteinase from the yeast Candida albicans

1981 • 181 citations

Purification and characterization of a proteolytic enzyme from Candida albicans

1968 • 157 citations

Interaction of human cathepsin D with the inhibitor pepstatin

1976 • 150 citations

Isolation and Characterization of Proteinase from Candida albicans: Substrate Specificity

1984 • 143 citations

Correlative relationship between proteinase production, adherence and pathogenicity of various strains ofCandida albicans

1986 • 135 citations

Sequence of the Candida albicans gene encoding the secretory aspartate proteinase.

1991 • 133 citations

Evidence for a Role for Secreted Aspartate Proteinase of Candida albicans in Vulvovaginal Candidiasis

1990 • 129 citations

The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant

1990 • 127 citations

Sequence of theCandida albicansgene encoding the secretory aspartate proteinase

1991 • 91 citations

Mechanism of inhibition of pepsin by pepstatin

1980 • 81 citations

Comparative production and rapid purification of Candida acid proteinase from protein-supplemented cultures

1990 • 78 citations

Activation of the plasma kallikrein-kinin system by Candida albicans proteinase

1990 • 74 citations

Design and synthesis of new fluorogenic HIV protease substrates based on resonance energy transfer

1990 • 64 citations

Modulation of Experimental Systemic Murine Candidosis by Intravenous Pepstatin

1990 • 63 citations

A Specific Inhibitor of Keratinolytic Proteinase from Candida albicans Could Inhibit the Cell Growth of C. albicans

1985 • 45 citations

Improvements of the Anson assay for measuring proteolytic activities in acidic pH range

1978 • 28 citations

Recombinant human prorenin from CHO cells: Expression and purification

1990 • 22 citations

A Role of Secreted Proteinase of Candida albicans for the Invasion of Chick Chorio‐Allantoic Membrane

1989 • 21 citations

Sequence‐specific fragmentation from oligopeptides using plasma‐desorption mass spectrometry

1990 • 9 citations