Evidence for a Unique Long Chain Acyl-CoA Ester Binding Site on the ATP-regulated Potassium Channel in Mouse Pancreatic Beta Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1967 • 2,783 citations

Reconstitution of I _KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

1995 • 1,703 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Electrophysiology of the pancreatic β-cell

1989 • 1,123 citations

Single channel recording

1984 • 981 citations

Proteolytic enzymes; a practical approach

1991 • 786 citations

Sodium channels and gating currents.

1981 • 541 citations

Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

1996 • 532 citations

Direct regulation of ion channels by fatty acids

1991 • 407 citations

STUDIES IN OBESE‐HYPERGLYCEMIC MICE*

1965 • 373 citations

Proteolytic enzymes; a practical approach

1990 • 364 citations

The preparation of, and studies on, free cell suspensions from mouse pancreatic islets

1974 • 359 citations

Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets

1991 • 350 citations

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

1984 • 324 citations

Electrical Activity in Pancreatic Islet Cells

1968 • 301 citations

Activation of the ATP-sensitive K+ Channel by Long Chain Acyl-CoA

1996 • 167 citations

ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion

1990 • 143 citations

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic β-cells

1996 • 121 citations

The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas.

1991 • 114 citations

Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic ?-cells and HIT cells

1992 • 100 citations

Oscillations in KATP channel activity promote oscillations in cytoplasmic free Ca2+ concentration in the pancreatic beta cell.

1996 • 95 citations

Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic β-cells

1987 • 86 citations

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta‐cells.

1993 • 84 citations

Modification of L‐type calcium current by intracellularly applied trypsin in guinea‐pig ventricular myocytes.

1988 • 63 citations

Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin

1992 • 62 citations

Phosphate and thiophosphate group donating adenine and guanine nucleotides inhibit glibenclamide binding to membranes from pancreatic islets

1991 • 60 citations

Modification of K-ATP channels in pancreatic ?-cells by trypsin

1993 • 38 citations

Relationships between energy level and insulin secretion in isolated rat islets of langerhans

1991 • 23 citations