Comparison of Uptake Characteristics of Thymidine and Zidovudine in a Human intestinal Epithelial Model System

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

1986 • 1,032 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

1990 • 820 citations

Plasma and cerebrospinal fluid pharmacokinetics of 3′-azido-3′-deoxythymidine: A Novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases

1987 • 383 citations

Nucleoside and nucleobase transport in animal cells

1988 • 367 citations

Reversibility by dipyridamole of thallium-201 myocardial scan defects in patients with sarcoidosis

1988 • 366 citations

Permeation of Nucleosides, Nucleic Acid Bases, and Nucleotides in Animal Cells

1980 • 312 citations

Transport of nucleoside drugs in animal cells

1981 • 241 citations

Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier

1990 • 234 citations

3′-azido-3′-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion.

1987 • 224 citations

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2

1990 • 224 citations

The influence of peptide structure on transport across Caco-2 cells.

1991 • 223 citations

Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro.

1987 • 201 citations

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2

1990 • 163 citations

Sodium-dependent nucleoside transport in mouse intestinal epithelial cells. Two transport systems with differing substrate specificities.

1988 • 159 citations

AIDS: Etiology, Diagnosis, Treatment, and Prevention

1989 • 142 citations

Sodium-dependent, concentrative nucleoside transport in cultured intestinal epithelial cells

1986 • 76 citations

Uridine uptake by isolated intestinal epithelial cells of guinea pig

1984 • 75 citations

Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).

1990 • 73 citations

Transport of a large neutral amino acid in a human intestinal epithelial cell line (Caco-2): uptake and efflux of phenylalanine

1992 • 66 citations

3′-Azido-2′,3′-Dideoxyuridine (AzddU): Comparative Pharmacokinetics with 3′-Azido-3′-Deoxythymidine (AZT) in Monkeys

1990 • 45 citations

3'-Deoxythymidin-2'-ene permeation of human lymphocyte H9 cells by nonfacilitated diffusion.

1991 • 43 citations

Pharmacodynamics of 2′,3′-dideoxycytidine: An inhibitor of human immunodeficiency virus

1990 • 40 citations

Nitrofurantoin Produces Oxidative Stress and Loss of Glutathione and Protein Thiols in the Isolated Perfused Rat Liver

1989 • 38 citations

Na+-dependent, active nucleoside transport in mouse spleen lymphocytes, leukemia cells, fibroblasts and macrophages, but not in equivalent human or pig cells; dipyridamole enhances nucleoside salvage by cells with both active and facilitated transport

1990 • 36 citations

Concentration and pH dependency of α-methyldopa absorption in rat intestine

1986 • 25 citations

Active transport of nucleosides and nucleoside drugs

1989 • 24 citations

Permeation and salvage of dideoxyadenosine in mammalian cells.

1989 • 23 citations

The effect of pH and concentration on α-methyldopa absorption in man

1986 • 21 citations

Intestinal absorption of alpha-methyldopa: in vitro mechanistic studies in rat small intestinal segments.

1987 • 19 citations

Uptake of 2′,3′-Dideoxyadenosine in Human Immunodeficiency Virus-Infected and Noninfected Human Cells

1989 • 14 citations

Membrane Transport of Nucleoside Analogues in Mammalian Cells

1989 • 12 citations

Sodium-dependent and inhibitor-insensitive uptake of adenosine by mouse peritoneal exudate cells

1990 • 11 citations

The Absorption and Excretion of Methyldopa Ingested Concomitantly with Amino Acids or Food Rich in Protein

1982 • 9 citations