A neurotoxic peripherin splice variant in a mouse model of ALS

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1995 • 1,424 citations

From charcot to lou gehrig: deciphering selective motor neuron death in als

2001 • 1,373 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

1986 • 711 citations

Amyotrophic Lateral Sclerosis

2001 • 437 citations

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.

1996 • 397 citations

Proximal axonal enlargement in motor neuron disease

1968 • 359 citations

Aggregation of Mutant Cu/Zn Superoxide Dismutase Proteins in a Culture Model of ALS

1997 • 355 citations

Deregulation of Cdk5 in a Mouse Model of ALS

2001 • 336 citations

Neurofilaments in Health and Disease

1998 • 282 citations

Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein (NF-L), during the development of the rat

1990 • 250 citations

Late Onset Death of Motor Neurons in Mice Overexpressing Wild-Type Peripherin

1999 • 239 citations

Glutamate Potentiates the Toxicity of Mutant Cu/Zn-Superoxide Dismutase in Motor Neurons by Postsynaptic Calcium-Dependent Mechanisms

1998 • 235 citations

Peripherin, a New Member of the Intermediate Filament Protein Family

1983 • 221 citations

Distribution of a novel 57 kDa intermediate filament (IF) protein in the nervous system

1988 • 182 citations

Peripherin and Neurofilament Protein Coexist in Spinal Spheroids of Motor Neuron Disease

1992 • 156 citations

Regulation of peripherin and neurofilament expression in regenerating rat motor neurons

1990 • 146 citations

The presence or absence of a vimentin-type intermediate filament network affects the shape of the nucleus in human SW-13 cells

1994 • 139 citations

Intermediate filaments and disease: mutations that cripple cell strength.

1994 • 132 citations

Differential regulation of peripherin and neurofilament gene expression in regenerating rat DRG neurons

1990 • 119 citations

Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α

2001 • 115 citations

Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects?

2000 • 95 citations

Desmin‐related myopathies in mice and man

2001 • 92 citations

Selective distribution of the 57 kDa neural intermediate filament protein in the rat CNS

1989 • 85 citations

Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits

1999 • 80 citations

Peripherin immunoreactive structures in amyotrophic lateral sclerosis.

1993 • 80 citations

Desmin splice variants causing cardiac and skeletal myopathy

2000 • 79 citations

Multiple mRNAs encode peripherin, a neuronal intermediate filament protein.

1989 • 77 citations

Nerve growth factor enhances the synthesis, phosphorylation, and metabolic stability of neurofilament proteins in PC12 cells.

1987 • 77 citations

Human synemin gene generates splice variants encoding two distinct intermediate filament proteins

2001 • 73 citations

Progress in Clinical Neurosciences: The Evidence for ALS as a Multisystems Disorder of Limited Phenotypic Expression

2001 • 72 citations

Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits

1999 • 63 citations

Mouse peripherin isoforms

2000 • 62 citations

Regulation of Peripherin in Mouse Neuroblastoma and Rat PC 12 Pheochromocytoma Cell Lines

1983 • 58 citations

A novel glial fibrillary acidic protein mRNA lacking exon 1

1995 • 58 citations

Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia

2002 • 57 citations

Peripherin assembles into homopolymers in SW13 cells

1995 • 46 citations

Peripherin and neurofilaments: expression and role during neural development.

1993 • 26 citations

Peripherin Is Tyrosine‐Phosphorylated at Its Carboxyl‐Terminal Tyrosine

1998 • 22 citations

The Structure of the Human Peripherin Gene (PRPH) and Identification of Potential Regulatory Elements

1994 • 19 citations