Disparate Effects of Triphenylethylene Antiestrogens on Estrogen and Progestin Biosyntheses by Cultured Rat Granulosa Cells*

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell differentiation.

1980 • 837 citations

Oestrogen and nuclear binding sites. Determination of specific sites by [3H]oestradiol exchange

1972 • 481 citations

Pituitary and Gonadal Hormones in Women during Spontaneous and Induced Ovulatory Cycles

1970 • 376 citations

High-affinity anti-oestrogen binding site distinct from the oestrogen receptor

1980 • 360 citations

Estrogen and Follicle Stimulating Hormone Interactions on Follicle Growth in Rats

1972 • 333 citations

How to analyze binding, enzyme and uptake data: The simplest case, a single phase

1982 • 262 citations

The agonistic-antagonistic properties of clomiphene: A review

1981 • 222 citations

Kinetics of gonadotropin binding by receptors by the rat testis. Analysis by a nonlinear curve-fitting method

1975 • 216 citations

Estradiol Receptor Content in Rat Granulosa Cells During Follicular Development: Modification by Estradiol and Gonadotropins

1975 • 213 citations

Antiestrogen-Binding Sites Distinct from the Estrogen Receptor: Subcellular Localization, Ligand Specificity, and Distribution in Tissues of the Rat*

1983 • 183 citations

Direct Inhibitory Effect of Gonadotropin-Releasing Hormone upon Follicle-Stimulating Hormone Induction of Luteinizing Hormone Receptor and Aromatase Activity in Rat Granulosa Cells*

1980 • 159 citations

Regulation of ovarian progestin production by epidermal growth factor in cultured rat granulosa cells.

1982 • 135 citations

Induction of functional prolactin receptors by follicle-stimulating hormone in rat granulosa cells in vivo and in vitro.

1979 • 131 citations

Characterization and quantitation of antiestrogen binding sites in estrogen receptor-positive and -negative human breast cancer cell lines.

1983 • 120 citations

Mechanisms of oestrogen antagonism by nonsteroidal antioestrogens

1982 • 97 citations

Effect of Clomiphene on the Uptake of Estradiol by the Anterior Hypothalamus and Hypophysis

1968 • 91 citations

DIRECT ENHANCEMENT OF GONADOTROPIN-STIMULATED OVARIAN ESTROGEN BIOSYNTHESIS BY ESTROGEN AND CLOMIPHENE CITRATE

1982 • 89 citations

Radioimmunoassay Data Processing with a Small Programmable Calculator

1980 • 76 citations

Estrogen Augmentation of Gonadotropin-Stimulated Progestin Biosynthesis in Cultured Rat Granulosa Cells*

1983 • 74 citations

Effect of Stilbœstrol on the Ovaries of Hypophysectomized Rats

1940 • 69 citations

Action of MER-25 and of Clomiphene on the Human Ovary

1963 • 66 citations

Evidence for estradiol binding sites in the hypothalamus—Effect of drugs

1967 • 48 citations

Specific binding and biological response of antiestrogens in the fetal uterus of the guinea pig.

1980 • 43 citations

Estrogenic Stimulation of the Antiestrogen Specific Binding Site in Rat Uterus and Liver*

1983 • 43 citations

A HIGH-AFFINITY BINDING SITE FOR THE ANTIOESTROGENS, TAMOXIFEN AND CI 628, IN IMMATURE RAT UTERINE CYTOSOL WHICH IS DISTINCT FROM THE OESTROGEN RECEPTOR

1981 • 41 citations

Estrogen Receptor in Rabbit Ovaries and Effects of Antiestrogen on Progesterone Production*

1981 • 37 citations

Effects of clomiphene cis and trans isomers on sterol metabolism in the rat

1970 • 22 citations

AN ENDOGENOUS LIGAND FOR THE TRIPHENYLETHYLENE ANTIESTROGEN BINDING SITE

1983 • 20 citations

An effect in vivo of clomiphene on the rate of conversion of androstenedione-C14 to estrone-C14 and estradiol-C14 by the canine ovary

1968 • 17 citations

Steroid sulphate secretion by the human ovary In vitro: Influence of gonadotrophins, cyclofenil and clomiphene

1980 • 8 citations

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