The Bacterial and Mouse Mammary Tumor Virus Superantigens; Two Different Families of Proteins with the Same Functions

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1988 • 608 citations

A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

1991 • 394 citations

High-affinity binding of staphylococcal enterotoxins A and B to HLA-DR

1989 • 388 citations

The Mitogenic Effects of Endotoxin and Staphylococcal Enterotoxin B on Mouse Spleen Cells and Human Peripheral Lymphocytes

1970 • 385 citations

T‐Cell Responses to Mls and to Bacterial Proteins that Mimic its Behavior^#

1989 • 337 citations

A maternally inherited superantigen encoded by a mammary tumour virus

1991 • 335 citations

Selective Depletion in HIV Infection of T Cells that Bear Specific T Cell Receptor V _β Sequences

1991 • 322 citations

Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice

1991 • 307 citations

Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomes

1991 • 297 citations

An endogenous retrovirus mediating deletion of αβ T cells?

1991 • 278 citations

Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus

1991 • 277 citations

Class II MHC Molecules Are Specific Receptors for Staphylococcus Enterotoxin A

1989 • 267 citations

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.

1990 • 253 citations

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1990 • 242 citations

Transgenic mouse mammary tumor virus superantigen expression prevents viral infection

1992 • 223 citations

Mutations defining functional regions of the superantigen staphylococcal enterotoxin B.

1992 • 208 citations

Requirement for Cotolerogenic Gene Products in the Clonal Deletion of I-E Reactive T Cells

1990 • 193 citations

Viral receptors of the immunoglobulin superfamily

1989 • 178 citations

Binding of staphylococcal enterotoxin A to HLA-DR on B cell lines.

1989 • 169 citations

Evidence for a viral superantigen in humans

1992 • 167 citations

The region of mouse mammary tumor virus DNA containing the long terminal repeat includes a long coding sequence and signals for hormonally regulated transcription.

1982 • 152 citations

Superantigen implicated in dependence of HIV-1 replication in T cells on TCR V β expression

1992 • 152 citations

Stimulation of B10.BR T cells with superantigenic staphylococcal toxins.

1990 • 143 citations

Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complex class ii isotypes

1989 • 118 citations

Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules.

1990 • 110 citations

The Effect of Staphylococcal Enterotoxins on the Primary in Vitro Immune Response

1975 • 107 citations

Staphylococcal enterotoxin B and toxic shock syndrome toxin-1 bind to distinct sites on HLA-DR and HLA-DQ molecules.

1989 • 105 citations

Induction of Neonatal Tolerance to Mls^aAntigens by CD8⁺T Cells

1990 • 103 citations

Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.

1991 • 95 citations

Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a)

1992 • 93 citations

The immunobiology of the T cell response to Mls-locus-disparate stimulator cells. I. Unidirectionality, new strain combinations, and the role of Ia antigens.

1985 • 85 citations

The mouse mammary tumour virus long terminal repeat encodes a type II transmembrane glycoprotein.

1992 • 84 citations

The effects of chronic infection with a superantigen-producing virus.

1992 • 83 citations

The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens.

1992 • 83 citations

Structural analysis of a mouse mammary tumor virus superantigen.

1992 • 81 citations

Activation of murine T cells by toxic shock syndrome toxin-1. The toxin-binding structures expressed on murine accessory cells are MHC class II molecules.

1989 • 70 citations

Stimulation of mouse lymphocytes by a mitogen derived from Mycoplasma arthritidis (MAM). VIII. Selective activation of T cells expressing distinct V beta T cell receptors from various strains of mice by the "superantigen" MAM.

1990 • 70 citations

T lymphocyte responses to Mls locus antigens involve recognition of H-2 I region gene products

1977 • 65 citations

Segregation patterns of endogenous mouse mammary tumor viruses in five recombinant inbred strain sets

1990 • 60 citations

Further Evidence for the Protein Coding Potential of the Mouse Mammary Tumor Virus Long Terminal Repeat: Nucleotide Sequence of an Endogenous Proviral Long Terminal Repeat

1983 • 60 citations

T cell responses to Mls determinants are restricted by cross-reactive MHC determinants.

1985 • 60 citations

Localization of an immune functional site on staphylococcal enterotoxin A using the synthetic peptide approach.

1989 • 59 citations

Mutants of staphylococcal toxic shock syndrome toxin 1: mitogenicity and recognition by a neutralizing monoclonal antibody

1990 • 56 citations

Characterization, chromosome assignment, and segregation analysis of endogenous proviral units of mouse mammary tumor virus

1986 • 51 citations

Structural basis for differential binding of staphylococcal enterotoxin A and toxic shock syndrome toxin 1 to class II major histocompatibility molecules.

1991 • 39 citations

Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype.

1989 • 37 citations

Physiologic expression of two superantigens in the BDF1 mouse.

1991 • 36 citations

Biological and immunological properties of the carboxyl terminus of staphylococcal enterotoxin C1

1989 • 35 citations

Molecular cloning and sequencing of the Mtv-1 LTR: Evidence for a LTR sequence alteration

1989 • 31 citations

The I-Aβb region (65–85) is a binding site for the superantigen, staphylococcal enterotoxin A

1990 • 29 citations

T-cell Recognition of Superantigens: Inside or Outside the Groove?

1989 • 16 citations

A congenic line of the BALB/c mouse strain with the endogenous mouse mammary tumor virus proviral gene Mtv-3: tissue-specific expression and correlation with resistance to mouse mammary tumor virus infection and tumorigenesis.

1990 • 16 citations

Disruptions in intracellular membrane trafficking and structure preclude the glucocorticoid-dependent maturation of mouse mammary tumor virus proteins in rat hepatoma cells.

1992 • 10 citations