Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

2003 • 2,949 citations

T-Cell Function and Migration — Two Sides of the Same Coin

2000 • 1,437 citations

ZAP-70 Expression as a Surrogate for Immunoglobulin-Variable-Region Mutations in Chronic Lymphocytic Leukemia

2003 • 1,366 citations

Lymphocyte traffic control by chemokines

2001 • 1,225 citations

IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a

2004 • 845 citations

Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1

2000 • 720 citations

Chemokines as regulators of T cell differentiation

2001 • 710 citations

Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's Patches

2002 • 502 citations

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

2003 • 443 citations

B-Cell Chronic Lymphocytic Leukemia: A Bird of a Different Feather

1999 • 408 citations

Glycogen synthase kinase 3: an emerging therapeutic target

2002 • 399 citations

Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1α

2005 • 299 citations

Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells

2005 • 288 citations

Stromal cell–derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G0/G1 transition in CD34+ cells: evidence for an autocrine/paracrine mechanism

2002 • 276 citations

Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cδ

2002 • 253 citations

CD38 expression is an important prognostic marker in chronic lymphocytic leukaemia

2002 • 225 citations

Requirement of Activation of JNK and p38 for Environmental Stress-Induced Erythroid Differentiation and Apoptosis and of Inhibition of ERK for Apoptosis

1999 • 221 citations

Description of a novel FR1 IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B cell malignancies.

1995 • 188 citations

Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells

2001 • 175 citations

FOXO Transcription Factors as Regulators of Immune Homeostasis: Molecules to Die for?

2003 • 161 citations

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines

2002 • 151 citations

Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis

2000 • 146 citations

Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)

2000 • 136 citations

Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration

2002 • 101 citations

The vitamin D3 analog EB1089 induces apoptosis via a p53-independent mechanism involving p38 MAP kinase activation and suppression of ERK activity in B-cell chronic lymphocytic leukemia cells in vitro

2003 • 101 citations

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

2003 • 75 citations

Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor–1 enhances their ability to engraft NOD/SCID mice

2002 • 71 citations

Activation of extracellular signal‐regulated kinases ERK1 and ERK2 induces Bcl‐xL up‐regulation via inhibition of caspase activities in erythropoietin signaling

2003 • 69 citations

Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways

2003 • 53 citations

Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway.

2001 • 49 citations

An old kinase on a new path: Raf and apoptosis

2002 • 48 citations

Disparate expression of the PTEN gene: a novel finding in B‐cell chronic lymphocytic leukaemia (B‐CLL)

2003 • 45 citations

Stromal derived factor-1α (SDF-1α) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway

2001 • 41 citations

Immunobiology of chronic lymphocytic leukemia

2003 • 21 citations

Cited By (0)

Loading...