Comparative mutational analysis of wild-type and stretched tRNA3(Leu) gene promoters.

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

A nuclear extract of xenopus laevis oocytes that accurately transcribes 5S RNA genes

1978 • 323 citations

Oligonucleotide directed mutagenesis of the human β-globin gene: a general method for producing specific point mutations in cloned DNA

1981 • 207 citations

Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase III

1983 • 177 citations

Specific transcription of homologous class III genes in yeast-soluble cell-free extracts.

1982 • 154 citations

Effects of tRNATyr point mutations on the binding of yeast RNA polymerase III transcription factor C.

1986 • 147 citations

Isolation of a class C transcription factor which forms a stable complex with tRNA genes.

1984 • 126 citations

Compilation of sequences of tRNA genes

1984 • 126 citations

A split binding site for transcription factor tau on the tRNA3Glu gene.

1985 • 123 citations

Mutations at the yeast SUP4 tRNATyr locus: DNA sequence changes in mutants lacking suppressor activity

1980 • 115 citations

tRNA gene transcription in yeast: Effects of specified base substitutions in the intragenic promoter

1983 • 108 citations

Selective proteolysis defines two DNA binding domains in yeast transcription factor τ

1986 • 104 citations

Differential binding of a S. cerevisiae RNA polymerase III transcription factor to two promoter segments of a tRNA gene.

1984 • 93 citations

A large region controls tRNA gene transcription

1985 • 83 citations

Specific interactions of Saccharomyces cerevisiae proteins with a promoter region of eukaryotic tRNA genes.

1982 • 75 citations

Gene size differentially affects the binding of yeast transcription factor tau to two intragenic regions.

1987 • 75 citations

Anin vitroRNA polymerase III system fromS. cerevisiae:effects of deletions and point mutations uponSUP4gene transcription

1982 • 69 citations

Transcription and processing of a yeast tRNA gene containing a modified intervening sequence

1980 • 68 citations

Structural features of yeast tRNA genes which affect transcription factor binding.

1984 • 59 citations

Effects of temperature and single-stranded DNA on the interaction of an RNA polymerase III transcription factor with a tRNA gene

1985 • 52 citations

Mutation in the A block of the yeast tRNA3Leu gene that allows transcription but abolishes splicing and 5′-end maturation

1983 • 39 citations

Deletion of the 3′ half of the yeast tRNA3Leu gene does not abolish promoter function in vitro

1981 • 36 citations

Role of RNA structure in splicing: Excision of the intervening sequence in yeast tRNA3leu is dependent on the formation of a D stem

1983 • 30 citations