Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Construction of Phylogenetic Trees

1967 • 3,637 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Bacterial evolution

1987 • 2,303 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

[69] Isolation of the cell membrane of Halobacterium halobium and its fractionation into red and purple membrane

1974 • 1,690 citations

The Phylogeny of Prokaryotes

1980 • 1,457 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Aligning amino acid sequences: Comparison of commonly used methods

1985 • 400 citations

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.

1985 • 346 citations

Compilation and analysis of eukaryotic POL II promoter sequences

1986 • 345 citations

Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II

1987 • 306 citations

Eocytes: a new ribosome structure indicates a kingdom with a close relationship to eukaryotes.

1984 • 277 citations

New versatile cloning and sequencing vectors based on bacteriophage M13

1983 • 263 citations

Analysis of transcription in the archaebacteriumSulfolobusindicates that archaebacterial promoters are homologous to eukaryotic pol II promoters

1988 • 216 citations

Archaebacterial phylogeny: Perspectives on the Urkingdoms

1986 • 212 citations

The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter

1987 • 201 citations

Archaebacteria and eukaryotes possess DNA-dependent RNA polymerases of a common type.

1983 • 158 citations

An archaebacterial promoter element for stable RNA genes with homology to the TATA box of higher eukaryotes

1988 • 156 citations

An Improved strategy for rapid direct sequencing of both strands of long DNA molecules cloned in a plasmid

1983 • 153 citations

The primary structure otE. coliRNA porymerase. Nucleotide sequence of the rpoC gene and amino acid sequence of the β′-sabunit

1982 • 137 citations

Sequence, organization, transcription and evolution of RNA polymerase subunit genes from the archaebacterial extreme halophiles Halobacterium halobium and Halococcus morrhuae

1989 • 137 citations

RPA190, the gene coding for the largest subunit of yeast RNA polymerase A.

1988 • 124 citations

Trypanosoma brucei contains two RNA polymerase II largest subunit genes with an altered C-terminal domain

1989 • 116 citations

Comparative evaluation of gene expression in archaebacteria

1988 • 116 citations

Experimental manipulation of gene expression

1983 • 115 citations

Sequence of the 16S rRNA gene from the thermoacidophilic archaebacteriumSulfolobus solfataricus and its evolutionary implications

1985 • 101 citations

Reintedness of archaebacterial RNA polymerase core subunits to their eubacterial and eultaryotic equivalents

1988 • 82 citations

Structural homology between different archaebacterial DNA-dependent RNA polymerases analyzed by immunological comparison of their components

1983 • 81 citations

Gene organization and structure of two transcriptional units from Methanococcus coding for ribosomal proteins and elongation factors

1989 • 58 citations

Analysis of higher-primate phylogeny from transversion differences in nuclear and mitochondrial DNA by Lake's methods of evolutionary parsimony and operator metrics.

1988 • 51 citations

Novel expression of the ribosomal RNA genes in the extreme thermophile and archaebacterium Desulfurococcus mobilis

1987 • 50 citations

Determining evolutionary distances from highly diverged nucleic acid sequences: Operator metrics

1987 • 49 citations

Structure and sequence of the gene for the largest subunit of trypanosomal RNA polymerase III

1988 • 42 citations

The nucleotide sequence of the gene coding for the 16S rRNA from the archaebacterium Halobacterium halobium

1985 • 39 citations

A Form of the DNA‐Dependent RNA Polymerase of Halobacterium halobium, Containing an Additional Component, Is Able to Transcribe Native DNA

1983 • 18 citations