Differential effects of ciprofibrate on renal and hepatic cytochrome P450 2E1 expression

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature

1993 • 1,663 citations

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1991 • 1,173 citations

Fatty Liver in the Rat after Prolonged Intake of Ethanol with a Nutritionally Adequate New Liquid Diet

1967 • 604 citations

Oxidative and reductive metabolism by cytochrome P450 2E1

1992 • 557 citations

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

1987 • 317 citations

Ethanol-, fasting-, and aceton-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies

1988 • 316 citations

Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

1989 • 277 citations

Metabolic aspects of peroxisomal β-oxidation

1991 • 277 citations

Bioactivation of Halogenated Hydrocarbons by Cytochrome P4502E1

1993 • 270 citations

Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA

1993 • 216 citations

Induction of peroxisomal β-oxidation in rat liver by high-fat diets

1980 • 215 citations

The induction of a specific form of cytochrome P-450 (P-450j) by fasting

1987 • 212 citations

Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

1987 • 206 citations

Multiple mechanisms in the regulation of ethanol‐inducible cytochrome P450IIE1

1990 • 199 citations

Effects of fat content in the diet on hepatic peroxisomes of the rat

1980 • 171 citations

Changes in Peroxisomal Fatty Acid Oxidation in the Diabetic Rat Liver

1981 • 163 citations

Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase.

1987 • 159 citations

Cloning and characterisation of the abundant cytoplasmic 7S RNA from mouse cells

1982 • 150 citations

Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats.

1993 • 143 citations

Induction of cytochrome P450IIE1 in the obese overfed rat.

1991 • 143 citations

Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats

1988 • 140 citations

Free Acetate Production by Rat Hepatocytes during Peroxisomal Fatty Acid and Dicarboxylic Acid Oxidation

1989 • 129 citations

Receptor-mediated mechanisms of peroxisome proliferators

1992 • 114 citations

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat.

1993 • 101 citations

Physiological Role of Peroxisomal β-Oxidation in Liver of Fasted Rats

1980 • 96 citations

Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA,

1993 • 94 citations

Expression of multiple forms of cytochrome P450 mRNAs in primary cultures of rat hepatocytes maintained on matrigel.

1993 • 91 citations

Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes

1990 • 87 citations

Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet.

1992 • 74 citations

Evidence for increased translational efficiency in the induction of P450IIE1 by solvents: Analysis of P450IIE1 mRNA polyribosomal distribution

1990 • 59 citations

Molecular regulation of ethanol-inducible cytochrome P450-IIEI in hamsters

1988 • 57 citations

Cytochrome P450 changes in rats with streptozocin-induced diabetes

1994 • 45 citations

Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes.

1995 • 40 citations

Suppression of hepatic levels of an ethanol-inducible P-450DM/j by growth hormone: relationship between the increased level of P-450DM/j and depletion of growth hormone in diabetes.

1989 • 37 citations

[26] CYP4A subfamily: Functional analysis by immunohistochemistry and in Situ hybridization

1991 • 32 citations

The effect of high-fat diets on microsomal lauric acid hydroxylation in rat liver

1986 • 32 citations

Ethanol interferes with regeneration-associated changes in biotransforming enzymes: A potential mechanism underlying ethanol's carcinogenicity?

1991 • 30 citations

Induction of rabbit hepatic microsomal cytochrome P-450 by imidazole: Enhanced metabolic activity and altered substrate specificity

1984 • 25 citations

Pretranslational regulation of cytochrome P4504A1 by free fatty acids in primary cultures of rat hepatocytes.

1994 • 25 citations

Enhanced expression of rat hepatic CYP2B1/2B2 and 2E1 by pyridine: differential induction kinetics and molecular basis of expression.

1993 • 25 citations

Peroxisomal oxidases in various tissues of diabetic rats

1991 • 23 citations

Alterations in cytochrome p‐450 levels in adult rats following neonatal exposure to xenobiotics

1993 • 17 citations

Regulation of renal cytochrome P450s by thyroid hormone in diabetic rats

1993 • 13 citations

Pyridine induction of Sprague-Dawley rat renal cytochrome P4502E1: immunohistochemical localization and quantitation

1995 • 9 citations

Involvment of glutamalergic transmission in development of ethanol tolerance

1995 • 1 citations