Co‐expression of B7‐1 and ICAM‐1 on tumors is required for rejection and the establishment of a memory response

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

A Theory of Self-Nonself Discrimination

1970 • 1,700 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

1992 • 1,156 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule

1992 • 820 citations

Specific Acceptance of Cardiac Allograft After Treatment with Antibodies to ICAM-1 and LFA-1

1992 • 737 citations

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.

1994 • 681 citations

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1991 • 660 citations

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

1993 • 563 citations

Immunobiology of Tissue Transplantation: A Return to the Passenger Leukocyte Concept

1983 • 524 citations

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.

1993 • 494 citations

Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

1994 • 492 citations

B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.

1989 • 487 citations

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

1994 • 482 citations

Biologic Therapy of Cancer

1992 • 476 citations

Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecules

1994 • 414 citations

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.

1991 • 349 citations

The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.

1991 • 335 citations

Costimulation of T cells for tumor immunity

1993 • 324 citations

Structure of the gene of tum− transplantation antigen P91A: The mutated exon encodes a peptide recognized with Ld by cytolytic T cells

1989 • 296 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules.

1993 • 274 citations

In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression.

1994 • 196 citations

Local cytokine availability elicits tumor rejection and systemic immunity through granulocyte-T-lymphocyte cross-talk.

1992 • 187 citations

T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells.

1994 • 174 citations

CD28 ligation in T-cell activation: evidence for two signal transduction pathways

1990 • 173 citations

Roles of multiple accessory molecules in T-cell activation

1991 • 167 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

Requirements for CD28-dependent T cell-mediated cytotoxicity.

1993 • 125 citations

Reduced contact sensitivity reactions in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1.

1993 • 120 citations

Functional characterization of LFA-1 antigens in the interaction of human NK clones and target cells.

1985 • 114 citations

Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant.

1993 • 110 citations

Cell-mediated cytotoxicity

1993 • 108 citations

Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increase of intracellular Ca2+ levels.

1992 • 106 citations

CD4⁺8⁻ help prevents rapid deletion of CD8⁺ cells after a transient response to antigen

1993 • 88 citations

IL-4 and IL-2 upregulate the expression of antigen B7, the B cell counterstructure to T cell CD28: an amplification mechanism for T-B cell interactions

1991 • 85 citations

Differential regulatory effects of intercellular adhesion molecule-1 on costimulation by the CD28 counter-receptor B7.

1992 • 78 citations

Interleukin 2 activated tumor inhibition in vivo depends on the systemic involvement of host immunoreactivity.

1987 • 76 citations

Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.

1993 • 23 citations

Role of adhesion molecules in the immune reaction to M-MSV-induced tumors.

1992 • 6 citations