Heme Deficiency and Phosphorylation of Ribosome‐Associated Proteins

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A simple method for the preparation of 32P-labelled adenosine triphosphate of high specific activity

1964 • 1,880 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

Initiation of Eukaryotic Protein Synthesis: [Met-tRNAf.40S Ribosome] Initiation Complex Catalysed by Purified Initiation Factors in the Absence of mRNA

1973 • 306 citations

Initiation of protein synthesis: Evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit

1973 • 296 citations

Control of globin synthesis: The role of heme

1972 • 257 citations

Factors affecting the rate of protein synthesis in lysate systems from reticulocytes

1968 • 238 citations

The effect of hemin on the synthesis of globin

1965 • 231 citations

Control of Protein Synthesis in Reticulocyte Lysates by Haemin

1973 • 201 citations

Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte.

1976 • 200 citations

Stimulation of globin-chain initiation by hemin in the reticulocyte cell-free system.

1968 • 184 citations

Purification and physical properties of homogeneous initiation factor MP from rabbit reticulocytes

1975 • 151 citations

Protein phosphorylation and bio-regulation

1980 • 140 citations

Protein Synthesis in Rabbit Reticulocytes

1973 • 138 citations

Control of reticulocyte polyribosome content and hemoglobin synthesis by heme

1966 • 136 citations

Protein Synthesis Initiation in Eukaryotes

1973 • 131 citations

Additional evidence that the hemin-controlled translational repressor from rabbit reticulocytes is a protein kinase

1977 • 122 citations

[45] Isolation of protein kinases from reticulocytes and phosphorylation of initiation factors

1979 • 115 citations

Recognition of eukaryotic initiator tRNA by an initiation factor and the transfer of the methionine moiety into peptide linkage

1972 • 115 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: purification and characterization of heme-reversible translational inhibitor.

1978 • 108 citations

Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.

1978 • 107 citations

Characterization of Protein Kinases from Rabbit Reticulocytes

1974 • 103 citations

Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA and oxidized glutathione: indirect mode of action on polypeptide chain initiation.

1975 • 101 citations

Translational Control in Hemoglobin Synthesis

1969 • 99 citations

Analysis of Phosphorylation of Protein Synthesis Initiation Factor eIF‐2 by Two‐Dimensional Gel Electrophoresis

1978 • 93 citations

Mode of action of the hemin-controlled inhibitor of protein synthesis.

1978 • 90 citations

Identification and RNA-binding properties of an initiation factor capable of relieving translational inhibition induced by heme deprivation or double-stranded RNA

1974 • 87 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: Additional initiation factor required for formation of ternary complex (eIF-2·GTP·Met-tRNA _f ) and demonstration of inhibitory effect of heme-regulated protein kinase

1979 • 86 citations

A comparison of ribosomal proteins from rabbit reticulocytes phosphorylated in situ and in vitro

1976 • 84 citations

Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: Inhibition of interaction of Met-tRNA _f ^Met binding factor with another initiation factor in formation of Met-tRNA _f ^Met ·40S ribosomal subunit complexes

1978 • 80 citations

Mode of action of the hemin-controlled inhibitor of protein synthesis: studies with factors from rabbit reticulocytes.

1978 • 75 citations

Hemin control of globin synthesis: Effect of a translational repressor on Met-tRNAf binding to the small ribosomal subunit and its relation to the activity and availability of an initiation factor

1973 • 74 citations

Effect of hemin on site-specific phosphorylation of eukaryotic initiation factor 2.

1978 • 71 citations

In situ phosphorylation of the α subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase

1979 • 68 citations

Partial reaction of peptide initiation inhibited by phosphorylation of either initiation factor eIF-2 or 40S ribosomal proteins.

1977 • 61 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: characteristics of inhibition of protein synthesis by a translational inhibitor from heme-deficient lysates and its relationship to the initiation factor which binds Met-tRNAf.

1976 • 48 citations

Polyamines and protein synthesis. VI. Role of spermine in aminoacyl-tRNA formation

1970 • 38 citations

Identification of Initiation Factors and Ribosome-Associated Phosphoproteins by Two-Dimensional Polyacrylamide Gel Electrophoresis

1979 • 30 citations

[46] Phosphorylation of ribosomal-associated proteins in reticulocyte lysates

1979 • 22 citations