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Affinity of 22-oxa-1,25(OH)2D3 for 1,25-dihydroxyvitamin D receptor and its effects on the synthesis of osteocalcin in human osteosarcoma cells

Data up to Jan 2025

Published1990
Citations18
References16

Total Citations Per Year

Abstract

References (16)

SPECIFIC HIGH-AFFINITY RECEPTORS FOR 1,25-DIHYDROXYVITAMIN D3IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PRESENCE IN MONOCYTES AND INDUCTION IN T LYMPHOCYTES FOLLOWING ACTIVATION

1983 • 600 citations

1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells.

1980 • 503 citations

Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids

1984 • 500 citations

Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle.

1985 • 483 citations

1,25(OH) 2 ‐Vitamin D 3 receptors: gene regulation and genetic circuitry

1988 • 455 citations

1α, 25‐Dihydroxyvitamin D3 specific regulation of growth, morphology, and fibronectin in a human osteosarcoma cell line

1985 • 183 citations

Characterization of a human osteoblastic osteosarcoma cell line (SAOS-2) with high bone alkaline phosphatase activity

1987 • 176 citations

Synthetic studies of vitamin D3 analogues. VIII Synthesis of 22-oxavitamin D3 analogues.

1986 • 142 citations

Synthetic analogues of vitamin D3 with an oxygen atom in the side chain skeleton A trial of the development of vitamin D compounds which exhibit potent differentiation‐inducing activity without inducing hypercalcemia

1987 • 135 citations

A SYNTHETIC ANALOGUE OF VITAMIN D3, 22-OXA-lα,25-DIHYDROXYVITAMIN D3IS A POTENT MODULATOR OF IN VIVO IMMUNOREGULATING ACTIVITY WITHOUT INDUCING HYPERCALCEMIA IN MICE

1989 • 106 citations

1,25-Dihydroxyvitamin D3 increases bone alkaline phosphatase isoenzyme levels in human osteogenic sarcoma cells.

1983 • 86 citations

Effect of 1,25(OH)2D3 on its receptor mRNA levels and osteocalcin synthesis in human osteosarcoma cells

1990 • 84 citations

Mechanism of action of 1,25-dihydroxyvitamin D3-induced stimulation of alkaline phosphatase in cultured osteoblast-like cells

1983 • 31 citations

1α,25 (OH)2 vitamin D3: A steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and nongenomic mechanisms

1988 • 29 citations

Resistance to 1,25-Dihydroxyvitamin D3of Cultured Psoriatic Epidermal Keratinocytes Isolated from Involved and Uninvolved Skin*

1989 • 26 citations

Demonstration and characterization of 1,25-dihydroxyvitamin D3 receptors in human mononuclear blood cells

1984 • 17 citations

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