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The biology of macrophages: I General principles and properties

Data up to Jan 2025

Published1993
Citations60
References84

Total Citations Per Year

Abstract

References (84)

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1973 • 2,286 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

1983 • 1,918 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES

1968 • 1,492 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Macrophage deactivation by interleukin 10.

1991 • 1,253 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE

1964 • 804 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

1988 • 575 citations

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages.

1993 • 540 citations

IN VITRO SYNTHESIS AND SECRETION OF LYSOZYME BY MONONUCLEAR PHAGOCYTES

1974 • 525 citations

Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages*

1988 • 511 citations

Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma.

1990 • 507 citations

HEMOPOIETIC CELL GROWTH FACTORS AND THEIR RECEPTORS

1989 • 432 citations

Effect of Cyclic AMP on Release of Lysosomal Enzymes from Phagocytes

1971 • 380 citations

Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes.

1980 • 365 citations

Interleukin 1: the first interleukin

1990 • 342 citations

The costimulatory function of antigen-presenting cells

1990 • 304 citations

Studies on the mechanism of phagocytosis. II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes.

1976 • 296 citations

Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.

1992 • 273 citations

Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-alpha.

1992 • 251 citations

Isolation and characterization of a tumor necrosis factor binding protein from urine

1989 • 249 citations

Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.

1983 • 238 citations

Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection.

1993 • 223 citations

Receptor Binding and Activation of Polymorphonuclear Neutrophils by Tumor Necrosis Factor-Alpha

1987 • 219 citations

Mononuclear Phagocytes

1980 • 213 citations

Macrophage inflammatory protein-1 alpha activates basophils and mast cells.

1992 • 191 citations

Dissection of an inflammatory process induced by CD8+ T cells

1990 • 187 citations

Encyclopedia of immunology

1992 • 183 citations

Multiple receptors for endotoxin

1991 • 181 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. I. Detection of lipopolysaccharide-binding sites on splenocytes and splenocyte subpopulations.

1988 • 173 citations

Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.

1991 • 165 citations

Self-Renewal of Pulmonary Alveolar Macrophages: Evidence From Radiation Chimera Studies

1987 • 149 citations

Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms

1991 • 147 citations

A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha.

1987 • 142 citations

Prostaglandin synthesis by macrophages requires a specific receptor-ligand interaction.

1980 • 140 citations

Phenotypic transformation of macrophages to Langerhans cells in the skin.

1986 • 134 citations

Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms

1991 • 132 citations

Macrophage activation in vivo and in vitro

1977 • 129 citations

Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages.

1985 • 128 citations

The Intravascular Lifespan of Monocytes

1966 • 114 citations

Tissue Thromboplastin Activity of Isolated Human Monocytes

1978 • 111 citations

IgG Autoantibodies against Interleukin 1α in Sera of Normal Individuals

1989 • 93 citations

Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors

1991 • 93 citations

LPS induces altered phosphate labeling of proteins in murine peritoneal macrophages.

1986 • 88 citations

Cells of the Mononuclear Phagocyte System

1980 • 87 citations

Role of Na+/H+Exchange by Interferon-γ in Enhanced Expression of JE and I-AβGenes

1989 • 83 citations

In vitro biosynthesis of cold insoluble globulin (fibronectin) by mouse peritoneal macrophages

1979 • 82 citations

Production of blood coagulation factory V and tissue thromboplastin by macrophages in vitro

1981 • 68 citations

Receptors for Complement on Echinoid Phagocytes. I. The Opsonic Effect of Vertebrate Sera on Echinoid Phagocytosis

1982 • 60 citations

Synthesis of Complement Components C5, C6, C7, C8 and C9 in Vitro by Human Monocytes and Assembly of the Terminal Complement Complex

1986 • 58 citations

Studies, with a luminogenic peptide substrate, on blood coagulation Factor X/Xa produced by mouse peritoneal macrophages

1982 • 45 citations

Evidence that Tumour Necrosis Induced by Aminated β1‐3D Polyglucose is Mediated by a Concerted Action of Local and Systemic Cytokines

1989 • 39 citations

Secretion of tumor necrosis factor during fetal and neonatal development of the mouse: ontogenic inflammation.

1989 • 37 citations

A prothrombinase complex of mouse peritoneal macrophages

1989 • 36 citations

Dynamics of Blood Components and Peritoneal Fluid during Treatment of Murine E. coli Sepsis with β‐1,3‐D‐polyglucose Derivatives

1990 • 33 citations

Comparison of Peritoneal Macrophages from Germfree and Conventional Mice

1979 • 32 citations

Mononuclear Phagocytes

2016 • 31 citations

Localization of receptors and early events of phagocytosis in the macrophage

1975 • 31 citations

Phagocytosis of β‐1,3‐D‐Glucan‐Derivatized Microbeads by Mouse Peritoneal Macrophages Involves Three Different Receptors

1991 • 31 citations

Difference in the Effect of Immobilized Ligands on the Fc and C3 Receptors of Mouse Peritoneal Macrophages in Vitro

1978 • 28 citations

The Modulatory Effect of Lipoproteins on the Release of Interleukin 1 by Human Peritoneal Macrophages Stimulated with β‐1,3‐<scp>d</scp>‐Polyglucose Derivatives

1989 • 25 citations

Dynamics of Blood Components and Peritoneal Fluid during Treatment of Murine E. coli Sepsis with β‐1, 3‐D‐Polyglucose Derivatives

1990 • 25 citations

Macrophage Biology and Activation

1992 • 22 citations

Heparin Protein Interactions

1992 • 17 citations

The Comparative Pathology of Inflammation

1894 • 16 citations

In vitro interactions of murine peritoneal macrophages and sarcoma cells

1986 • 11 citations

Fibronectin Binds to Complement‐Coated Agarose Beads and Increases Their Association to Mouse Macrophages

1985 • 10 citations

MOUSE PERITONEAL MACROPHAGES CULTURED SERUM‐FREE DEPOSIT COMPLEMENT ON IgM‐COATED SHEEP ERYTHROCYTES IN VITRO

1987 • 8 citations

In vitro interactions of murine peritoneal macrophages and sarcoma cells

1986 • 5 citations

Macrophage Activation

1988 • 1 citations

Pathologisch-anatomische Mittheilungen aus dem Krankenhause zu Orenburg in Russland

1870 • 1 citations

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The biology of macrophages: I General principles and properties (1993) – European Journal Of Haematology | Metascience Observatory Explorer