The Escherichia coli Malonyl-CoA:Acyl Carrier Protein Transacylase at 1.5-Å Resolution.

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The α/β hydrolase fold

1992 • 2,024 citations

A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex

1991 • 1,112 citations

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

1969 • 1,060 citations

Modular Organization of Genes Required for Complex Polyketide Biosynthesis

1991 • 883 citations

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

1994 • 585 citations

Regulation of fatty acid biosynthesis in Escherichia coli

1993 • 578 citations

The molecular evolution of genes and proteins: a tale of two serines

1988 • 548 citations

Ribbon models of macromolecules

1987 • 519 citations

POLYKETIDE SYNTHESIS: Prospects for Hybrid Antibiotics

1993 • 369 citations

Isomorphous replacement and anomalous scattering

2010 • 195 citations

Stereospecific Acyl Transfers on the Erythromycin-Producing Polyketide Synthase

1994 • 165 citations

Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase.

1989 • 159 citations

Data Collection and Processing

1980 • 143 citations

A novel variant of the catalytic triad in the Streptomyces scabies esterase

1995 • 141 citations

Relationships among serine hydrolases: evidence for a common structural motif in triacylglyceride lipases and esterases

1991 • 132 citations

Horse Pancreatic Lipase

1994 • 118 citations

Enzymatic Synthesis of a Bacterial Polyketide from Acetyl and Malonyl Coenzyme A

1993 • 113 citations

An unusual buried polar cluster in a family of fungal lipases

1994 • 112 citations

Three-dimensional structure of acyl carrier protein determined by NMR pseudoenergy and distance geometry calculations

1988 • 104 citations

Molecular cloning and sequencing of the gene for mycocerosic acid synthase, a novel fatty acid elongating multifunctional enzyme, from Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guerin.

1992 • 102 citations

Studies on the mechanism of fatty acid synthesis

1971 • 85 citations

Studies on the Mechanism of Fatty Acid Synthesis

1966 • 84 citations

Cloning, nucleotide sequence, and expression of the Escherichia coli fabD gene, encoding malonyl coenzyme A-acyl carrier protein transacylase

1992 • 78 citations

The presence of a novel type of surface polysaccharide in Rhizobium meliloti requires a new fatty acid synthase‐like gene cluster involved in symbiotic nodule development

1993 • 71 citations

Synthesis of multimethyl-branched fatty acids by avian and mammalian fatty acid synthetase and its regulation by malonyl-CoA decarboxylase in the uropygial gland

1978 • 68 citations

Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA.

1989 • 64 citations

1.9-.ANG. Structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications

1991 • 56 citations

Is .gamma.-chymotrypsin a tetrapeptide acyl-enzyme adduct of .alpha.-chymotrypsin?

1989 • 48 citations

Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors

1993 • 46 citations

Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer

1985 • 39 citations

A Crystallographic Re-investigation into the Structure of Streptomyces griseus Proteinase A Reveals an Acyl-enzyme Intermediate

1994 • 20 citations

Isolation of a functional transferase component from the rat fatty acid synthase by limited trypsinization of the subunit monomer. Formation of a stable functional complex between transferase and acyl carrier protein domains.

1991 • 19 citations

Crystallization of the Malonyl Coenzyme A-Acyl Carrier Protein Transacylase from Escherichia coli

1994 • 16 citations

Isomorphous replacement with optimized anomalous scattering applied to protein crystallography

1990 • 15 citations