Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice

A Specific Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase

1994 • 800 citations

Growth Inhibition of Human Tumor Cells in Athymic Mice by Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies

1984 • 443 citations

Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts.

1982 • 185 citations

THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW)

1994 • 144 citations

The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice.

1991 • 111 citations

Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor.

1992 • 110 citations

Characterization of the metabolic turnover of epidermal growth factor receptor protein in A‐431 cells

1984 • 94 citations

Blockage of EGF Receptor Signal Transduction Causes Reversible Arrest of Normal and Immortal Human Mammary Epithelial Cells with Synchronous Reentry into the Cell Cycle

1993 • 81 citations

Protein tyrosine kinases as therapeutic targets in cancer chemotherapy and recent advances in the development of new inhibitors

1994 • 48 citations

Dependence of a human squamous carcinoma and associated paraneoplastic syndromes on the epidermal growth factor receptor pathway in nude mice.

1991 • 24 citations

Characterization of a membrane‐associated phosphotyrosyl protein phosphatase from the A431 human epidermoid carcinoma cell line

1989 • 15 citations

Protein-tyrosine kinases, oncogenes, and cancer.

1993 • 12 citations

Purification of a Phosphotyrosine Phesphatase That Dephosphorylates the Epidermal Growth Factor Receptor Autophosphorylation Sites

1988 • 3 citations