Antiarrhythmic Therapies for the Prevention of Sudden Cardiac Death

Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease?

2016 • 11,500 citations

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1992 • 5,885 citations

Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia

1996 • 4,078 citations

Decreased heart rate variability and its association with increased mortality after acute myocardial infarction

1987 • 3,955 citations

Beta blockade during and after myocardial infarction: An overview of the randomized trials

1985 • 3,248 citations

Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo

1991 • 3,106 citations

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration

1994 • 2,115 citations

ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction

1995 • 1,786 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure

1993 • 1,775 citations

Protective Effects of Aspirin against Acute Myocardial Infarction and Death in Men with Unstable Angina

1983 • 1,740 citations

A Clinical Trial of the Angiotensin-Converting–Enzyme Inhibitor Trandolapril in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1995 • 1,734 citations

An overview of randomized trials of rehabilitation with exercise after myocardial infarction.

1989 • 1,454 citations

Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction

1996 • 1,352 citations

The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction.

1984 • 1,306 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.

1993 • 1,240 citations

Amiodarone in Patients with Congestive Heart Failure and Asymptomatic Ventricular Arrhythmia

1995 • 1,199 citations

Effect of Amlodipine on Morbidity and Mortality in Severe Chronic Heart Failure

1996 • 1,182 citations

Nifedipine

1995 • 1,175 citations

Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT

1997 • 1,108 citations

The Risk of Myocardial Infarction Associated With Antihypertensive Drug Therapies

1995 • 970 citations

Effect of the Antiarrhythmic Agent Moricizine on Survival after Myocardial Infarction

1992 • 969 citations

Analysis and Interpretation of Treatment Effects in Subgroups of Patients in Randomized Clinical Trials

1991 • 954 citations

Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT

1997 • 946 citations

Randomised trial of low-dose amiodarone in severe congestive heart failure

1994 • 909 citations

The Effect of the Angiotensin-Converting–Enzyme Inhibitor Zofenopril on Mortality and Morbidity after Anterior Myocardial Infarction

1995 • 792 citations

Long-term outcome with the automatic implantable cardioverter-defibrillator

1989 • 734 citations

Ventricular Premature Beats and Mortality after Myocardial Infarction

1977 • 659 citations

The Recent Decline in Mortality From Coronary Heart Disease, 1980-1990<subtitle>The Effect of Secular Trends in Risk Factors and Treatment</subtitle>

1997 • 647 citations

Diverse mechanisms of unexpected cardiac arrest in advanced heart failure.

1989 • 571 citations

Effects of Prophylactic Antiarrhythmic Drug Therapy in Acute Myocardial Infarction

1993 • 568 citations

Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)

1992 • 540 citations

Calcium channel blockers in acute myocardial infarction and unstable angina: an overview.

1989 • 424 citations

Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). A randomized controlled trial

1996 • 395 citations

Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel antiarrhythmic study of infarct survival (BASIS)

1990 • 386 citations

A Comparison of Electrophysiologic Testing with Holter Monitoring to Predict Antiarrhythmic-Drug Efficacy for Ventricular Tachyarrhythmias

1993 • 361 citations

Automatic Implantable Cardioverter Defibrillators and Survival of Patients with Left Ventricular Dysfunction and Malignant Ventricular Arrhythmias

1988 • 342 citations

Recurrent Ventricular Fibrillation and Modes of Death in Survivors of Out-of-Hospital Ventricular Fibrillation

1975 • 336 citations

Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials.

1991 • 336 citations

Sulfinpyrazone in the Prevention of Sudden Death after Myocardial Infarction

1980 • 335 citations

Relationship of Premature Systoles to Coronary Heart Disease and Sudden Death in the Tecumseh Epidemiologic Study

1969 • 315 citations

Effects of Prophylactic Lidocaine in Suspected Acute Myocardial Infarction

1988 • 315 citations

Effect of amiodarone on mortality after myocardial infarction: A double-blind, placebo-controlled, pilot study

1992 • 300 citations

Long-term results of amiodarone therapy in patients with recurrent sustained ventricular tachycardia or ventricular fibrillation

1989 • 286 citations

Randomized antiarrhythmic drug therapy in survivors of cardiac arrest (the CASCADE study)

1993 • 283 citations

Long‐Term Survival and Use of Antihypertensive Medications in Older Persons

1995 • 277 citations

Prognostic Importance of Premature Beats Following Myocardial Infarction

1973 • 258 citations

Prognostic Implications of Asymptomatic Ventricular Arrhythmias: The Framingham Heart Study

1992 • 257 citations

ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group.

1995 • 250 citations

DIAGNOSTIC ERRORS DISCOVERED AT AUTOPSY

1974 • 245 citations

Clinical features of amiodarone-induced pulmonary toxicity.

1990 • 242 citations

Exploration of the Precision of Classifying Sudden Cardiac Death

1996 • 237 citations

Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors (the Cardiac Arrest Study Hamburg)

1994 • 234 citations

Intravenous amiodarone for recurrent sustained hypotensive ventricular tachyarrhythmias

1996 • 225 citations

Serum Magnesium in Acute Myocardial Infarction

1980 • 204 citations

Community study of the causes of "natural" sudden death.

1988 • 183 citations

Prevention of Sudden Cardiac Death After a First Myocardial Infarction by Pharmacologic or Surgical Antiadrenergic Interventions

1992 • 170 citations

Post-myocardial infarction mortality in patients with ventricular premature depolarizations. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Pilot Study.

1991 • 160 citations

Magnesium and cardiovascular disease

1993 • 146 citations

Beneficial effects of low dose amiodarone in patients with congestive cardiac failure: A placebo-controlled trial

1989 • 146 citations

Prospective, double-blind, placebo-controlled trial of low-dose amiodarone in patients with severe heart failure and asymptomatic frequent ventricular ectopy

1991 • 139 citations

Rationale, design, implementation, and baseline characteristics of patients in the dig trial: A large, simple, long-term trial to evaluate the effect of digitalis on mortality in heart failure

1996 • 128 citations

Five-year follow-up of 589 patients treated with amiodarone

1993 • 118 citations

Effect of propranolol in patients with myocardial infarction and ventricular arrhythmia

1986 • 117 citations

Meta-analysis of Empirical Long-term Antiarrhythmic Therapy After Myocardial Infarction

1989 • 105 citations

Influence of the Implantable Cardioverter/Defibrillator on Sudden Death and Total Mortality in Patients Evaluated for Cardiac Transplantation

1995 • 101 citations

Clinical significance of ventricular arrhythmias in patients with and without coronary artery disease

1980 • 100 citations

LIGNOCAINE PROPHYLAXIS IN ACUTE MYOCARDIAL INFARCTION: AN EVALUATION OF RANDOMISED TRIALS

1981 • 96 citations

Increased risk of death and cardiac arrest from encainide and flecainide in patients after non-Q-wave acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial

1991 • 95 citations

Interaction of ischaemia and encainide/flecainide treatment: a proposed mechanism for the increased mortality in CAST I.

1995 • 94 citations

Pathological view of sudden cardiac death.

1981 • 89 citations

A controlled trial of verapamil in patients after acute myocardial infarction: Results of the calcium antagonist reinfarction italian study (CRIS)

1996 • 82 citations

Effect of amiodarone therapy on mortality in patients with left ventricular dysfunction and asymptomatic complex ventricular arrhythmias: Argentine pilot study of sudden death and amiodarone (EPAMSA)

1995 • 76 citations

Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrhythmias and on mortality after acute myocardial infarction

1993 • 75 citations

Comparison of d,l -Sotalol and Implantable Defibrillators for Treatment of Sustained Ventricular Tachycardia or Fibrillation in Patients With Coronary Artery Disease

1996 • 73 citations

An Epidemiological Perspective of Sudden Death 26-Year Follow-Up in the Framingham Study

1984 • 70 citations

Clinical experience with sotalol in patients with drug-refractory ventricular Arrhythmias

1989 • 63 citations

Epidemiological studies on the relationship between magnesium intake and cardiovascular diseases.

1981 • 63 citations

Sotalol

1993 • 62 citations

Safety and efficacy of sotalol in patients with drug-refractory sustained ventricular tachyarrhythmias

1990 • 59 citations

Effectiveness of amiodarone on ventricular arrhythmias during and after acute myocardial infarction

1987 • 50 citations

INTRACELLULAR ELECTROLYTES IN CARDIAC FAILURE

1986 • 49 citations

Relationship of ventricular ectopy in men without apparent heart disease to occurrence of ischemic heart disease and sudden death

1981 • 49 citations

Implantable cardioverter-defibrillators are preferable to drugs as primary therapy in sustained ventricular tachyarrhythmias

1996 • 48 citations

A controlled trial of sotalol for 1 year after myocardial infarction.

1983 • 44 citations

Usefulness of d, I sotalol for suppression of chronic ventricular arrhythmias

1991 • 38 citations

Sotalol for refractory sustained ventricular tachycardia and nonfatal cardiac arrest

1988 • 35 citations

Adherence and arrhythmic mortality in the Cardiac Arrhythmia Suppression Trial (CAST)

1996 • 31 citations

Lidocaine to prevent ventricular fibrillation in the prehospital phase of suspected acute myocardial infarction: The North-Norwegian Lidocaine Intervention Trial

1992 • 27 citations

Critical review of the approaches to the prevention of sudden death

1993 • 25 citations

Design of a placebo-controlled clinical trial of long-acting diltiazem and aspirin versus aspirin alone in patients receiving thrombolysis with a first acute myocardial infarction

1995 • 24 citations

Mortality risk and patterns of practice in 4606 acute care patients with congestive heart failure. The relative importance of age, sex, and medical therapy. Clinical Quality Improvement Network Investigators

1996 • 23 citations

Effectiveness of sotalol for therapy of complex ventricular arrhythmias and comparisons with placebo and class I antiarrhythmic drugs

1990 • 21 citations

Secondary prevention of ischemic heart disease: a long-term controlled lidoflazine study.

1979 • 20 citations

What is an antiarrhythmic drug? From clinical trials to fundamental concepts

1990 • 19 citations

Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience

1992 • 17 citations

Early out-of-hospital lidocaine administration decreases the incidence of primary ventricular fibrillation in acute myocardial infarction

1993 • 17 citations

Implantable defibrillators are superior to d,I-sotalol for treatment of sustained ventricular tachycardia or fibrillation in patients with coronary artery disease

1996 • 17 citations

Amiodarone in Long Term Prophylaxis

1991 • 15 citations

Survival in patients declining implantable cardioverter-defibrillators

1991 • 11 citations

Management of patients with life-threatening sustained ventricular tachyarrhythmias—The role of guided antiarrhythmic drug therapy

1996 • 10 citations

Silent Myocardial Ischemia and Angina: Prevalence, Prognostic, and Therapeutic Significance

1989 • 8 citations

Results of randomized clinical trials of magnesium - can a consensus be reached?

1996 • 3 citations

[The comparative efficacy of verapamil, nifedipine and propranolol in patients with IHD and an enhanced risk of a fatal outcome].

1994 • 3 citations

Nonsustained Ventricular Tachycardia

1997 • 1 citations

Nonischemic Ventricular Tachycardia: Surgical or Medical Treatment?

1995 • 1 citations

Deleted Work

1955 • 0 citations