Colony-stimulating factors in the clinic

Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium

1988 • 961 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR TO HARVEST CIRCULATING HAEMOPOIETIC STEM CELLS FOR AUTOTRANSPLANTATION

1989 • 776 citations

Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer

1987 • 605 citations

Apparent role of the macrophage growth factor, CSF-1, in placental development

1987 • 506 citations

Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.

1991 • 454 citations

Granulocyte Colony-Stimulating Factor Enhances the Phagocytic and Bactericidal Activity of Normal and Defective Human Neutrophils

1991 • 323 citations

Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia

1990 • 289 citations

Recombinant human granulocyte-macrophage colony-stimulating factor reduces hematologic toxicity and widens clinical applicability of high-dose cyclophosphamide treatment in breast cancer and non-Hodgkin's lymphoma.

1990 • 203 citations

Administration of interleukin-6 stimulates multilineage hematopoiesis and accelerates recovery from radiation-induced hematopoietic depression

1991 • 194 citations

Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in de novo acute myeloid leukemia

1991 • 187 citations

Phase I trial of recombinant human macrophage colony-stimulating factor in patients with invasive fungal infections

1991 • 156 citations

The molecular control of blood cells

1988 • 146 citations

Combined therapy with recombinant granulocyte colony-stimulating factor and erythropoietin decreases hematologic toxicity from zidovudine

1991 • 133 citations

Blasts from patients with acute myelogenous leukemia express functional receptors for stem cell factor

1992 • 113 citations

A phase II trial of recombinant human granulocyte colony‐stimulating factor in the myelodysplastic syndromes

1991 • 96 citations

Recombinant human granulocyte-macrophage colony-stimulating factor accelerates neutrophil and monocyte recovery after allogeneic T-cell- depleted bone marrow transplantation

1992 • 93 citations

Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption.

1992 • 79 citations

Recombinant human granulocyte-macrophage colony-stimulating factor accelerates neutrophil and monocyte recovery after allogeneic T-cell- depleted bone marrow transplantation

1992 • 73 citations

Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis.

1991 • 73 citations

Simultaneous Administration of Granulocyte-Macrophage Colony-Stimulating Factor and Cytosine Arabinoside for the Treatment of High-Risk Myeloid Leukemia

1992 • 71 citations

Macrophage colony stimulating factor prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits

1992 • 63 citations

The cytokine CSF-1 (M-CSF) expressed by endometrial carcinomas in vivo and in vitro, may also be a circulating tumor marker of neoplastic disease activity in endometrial carcinoma patients

1990 • 55 citations

In vivo effects of macrophage colony‐stimulating factor on human monocyte function

1991 • 54 citations

Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels

1991 • 51 citations

Granulocyte colony-stimulating factor (G-CSF) receptors on acute myeloblasts leukaemia cells and their relationship with the proliferative response to G-CSF in clonogenic assay

1991 • 50 citations

In vivo production of interleukin-5, granulocyte-macrophage colony- stimulating factor, macrophages colony-stimulating factor, and interleukin-6 during intravenous administration of high-dose interleukin-2 in cancer patients [see comments]

1991 • 50 citations

The capacity of peripheral blood stem cells mobilised with chemotherapy plus G-CSF to repopulate irradiated marrow stroma in vitro is similar to that of bone marrow

1992 • 49 citations

Autotransplantation of peripheral blood stem cells mobilized by chemotherapy and recombinant human granulocyte colony‐stimulating factor in childhood neuroblastoma and non‐Hodgkin's lymphoma

1992 • 47 citations

Hematopoietic effects of a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein

1991 • 44 citations

Severe congenital neutropenia: clinical effects and neutrophil function during treatment with granulocyte colony-stimulating factor.

1991 • 36 citations

Recombinant human granulocyte-colony-stimulating factor in the treatment of patients with chronic benign granulocytopenia and congenital agranulocytosis (Kostmann's syndrome)

1992 • 30 citations

Synergistic effects of interleukin-1 beta and interleukin-3 on the expansion of human hematopoietic progenitor cells in liquid cultures

1991 • 27 citations

In vivo effects of granulocyte-macrophage colony-stimulating factor and interleukin-3 on clonal and non-clonal cell populations in patients with clonal hematopoietic disorders.

1991 • 27 citations

Failure of GM-CSF to influence the growth of small cell and non-small cell lung cancer cell lines in vitro

1991 • 19 citations

Enhancement by interleukin 4 of interleukin 2- or antibody-induced proliferation of lymphocytes from interleukin 2-treated cancer patients.

1990 • 17 citations

Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption

1992 • 17 citations

Clinical uses of growth factors

1992 • 15 citations

The molecular control of blood cells

1989 • 6 citations

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