Interaction of the EcoRV restriction endonuclease with the deoxyadenosine and thymidine bases in its recognition hexamer d(GATATC)

Facilitated Target Location in Biological Systems

1989 • 1,011 citations

Recognition of a DNA Operator by the Repressor of Phage 434: A View at High Resolution

1988 • 531 citations

Structure of the DNA-Eco RI Endonuclease Recognition Complex at 3 Å Resolution

1986 • 492 citations

The hydrogen bond in molecular recognition

1987 • 462 citations

Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis

1987 • 234 citations

Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis

1988 • 172 citations

Effects of functional group changes in the EcoRI recognition site on the cleavage reaction catalyzed by the endonuclease

1987 • 169 citations

Restriction and modification of a self-complementary octanucleotide containing the EcoRI substrate

1975 • 164 citations

The effects of base analogue substitutions on the cleavage by the EcoRI restriction endonuclease of octadeoxyribonucleotides containing modified EcoRI recognition sequences.

1986 • 131 citations

Discrimination between DNA sequences by the EcoRV restriction endonuclease

1989 • 124 citations

Probing the limits of protein-amino acid side chain recognition with the aminoacyl-tRNA synthetases. Discrimination against phenylalanine by tyrosyl-tRNA synthetases

1980 • 92 citations

The specificity of enzymic reactions aminoacyl-soluble RNA ligases

1966 • 91 citations

Modes of DNA cleavage by the EcoRV restriction endonuclease

1988 • 83 citations

Palindromic oiigonucleotides containing 7-deaza-2' -deoxyguanosine: solid-phasesynthesisof d[(p)GG*AATTCC] octamers and recognition by the endodeoxyribonncleaseEcoRI

1986 • 70 citations

Palindromic octa- and dodecanucleotides containing 2'-deoxytubercidin: synthesis, hairpin formation, and recognition by the endodeoxyribonuclease EcoRI

1987 • 69 citations

Establishing the misacylation/deacylation of the tRNA pathway for the editing mechanism of prokaryotic and eukaryotic valyl-tRNA synthetases

1979 • 62 citations

The cleavage site for the restriction endonuclease EcoRV is 5′-GAT/ATC-3′

1984 • 60 citations

Analysis of the recognition mechanism involved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynucleotides

1988 • 55 citations

The influence of the geometric properties of the active centre on the specificity of α‐chymotrypsin catalysis

1972 • 55 citations

Interaction of the HpaI endonuclease with synthetic oligonucleotides

1982 • 47 citations

Thymine methyls and DNA–protein interactions

1987 • 46 citations

Specificity of the Valyl Ribonucleic Acid Synthetase from Escherichia coli in the Binding of Valine Analogues

1970 • 46 citations

Minor-groove-modified oligonucleotides: synthesis of decadeoxynudeotides containing hypoxanthine, N²-methylguanine and 3-deazaadenine, and their interactions with restriction endonucleasesBgiII,Sau3AI, andMboI (Nucleosides and Nucleotides Part 75)

1987 • 45 citations

Oligonucleotide duplexes containing inosine, 7-deazainosine, tubercidin, nebularine and 7-deazanebularine as substrates for restriction endonucleasesHindII,SalI andTaqI

1986 • 44 citations

Synthesis of deoxyoligonucteotides containing 7-deazaadenine: recognition and cleavage by restriction endonucleaseBglII andSau3AI (Nucleosides and Nucleotides Part 551)

1984 • 40 citations

Interaction of EcoRII restriction and modification enzymes with synthetic DNA fragments. VI. The binding and cleavage of substrates containing nucleotide analogs

1985 • 39 citations

The cloning, purification and characterization of theEcoRV modification methylase

1988 • 35 citations

The EcoRI restriction endonuclease, covalently closed DNA and ethidium bromide

1981 • 27 citations

Synthesis of decadeoxyribonucleotides containing 5-modified uracils and their interactions with restriction endonucleasesBglII,Sau3AI andMboI (Nucleosides and Nudeotides 82¹)

1988 • 25 citations

How does EcoRI cleave its recognition site on DNA?

1983 • 21 citations

Interaction of the restriction endonucleaseScaI with its substrates

1985 • 18 citations