Stimulation of gastrointestinal motility by loperamide in dogs

Inhibition of gastric emptying and drug absorption by narcotic analgesics.

1975 • 270 citations

Rate of flow of digesta and electrical activity of the small intestine in dogs and sheep.

1975 • 202 citations

Mechanism of the Antidiarrheal Effect of Loperamide

1984 • 195 citations

Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.

1984 • 136 citations

Centrally and peripherally mediated inhibition of intestinal motility by opioids

1979 • 108 citations

Abnormalities in gastrointestinal motor activity in patients with short bowels: Effect of a synthetic opiate

1983 • 96 citations

Electrical and extraluminal contractile-force activity of the duodenum of the dog

1965 • 84 citations

Diurnal changes in gastric motor activity in conscious dogs

1977 • 76 citations

Human intestinal motor activity and transport: Effects of a synthetic opiate

1986 • 72 citations

EFFECT OF MORPHINE AND DILAUDID ON THE ILEUM AND OF MORPHINE, DILAUDID AND ATROPINE ON THE COLON OF MAN

1942 • 67 citations

Effect of lidamidine hydrochloride and loperamide on gastric emptying and transit of the small intestine

1986 • 61 citations

Central and peripheral control of gastrointestinal and colonic motility by endogenous opiates in conscious dogs

1985 • 59 citations

Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test.

1985 • 57 citations

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 3: in vitro studies on the peristaltic reflex and other experiments on isolated tissues.

1974 • 48 citations

Diurnal changes in colonic motor profile in conscious dogs

1983 • 44 citations

NALOXONE INHIBITS THE ANTI‐DIARRHOEAL ACTIVITY OF LOPERAMIDE

1979 • 43 citations

EFFECTS OF MORPHINE AND SOME OTHER OPIUM ALKALOIDS ON THE MUSCULAR ACTIVITY OF THE ALIMENTARY CANAL I. ACTION ON THE SMALL INTESTINE IN UNANESTHETIZED DOGS AND MAN

1926 • 40 citations

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 2: in vivo parenteral pharmacology and acute toxicity in mice. Comparison with morphine, codeine and diphenoxylate.

1974 • 37 citations

Subcutaneous morphine reduces intestinal propulsion in rats partly by a central action

1981 • 33 citations

Differential Response of Longitudinal and Circular Muscles of Intact Canine Colon to Morphine and Bethanechol

1971 • 24 citations

Distribution of loperamide in the intestinal wall

1979 • 24 citations

Local inhibition of myoelectrical activity of human colon by loperamide

1984 • 21 citations

A micro-computerised system to measure the colonic contractile activity. Application to pharmacological tests in dogs

1980 • 16 citations

Comparative effects of morphine and cyclazocine on gastrointestinal motility in conscious dogs.

1984 • 14 citations

EFFECTS OF LOPERAMIDE ON THE MOTILITY OF THE ISOLATED INTESTINE IN GUINEA PIGS, RATS AND DOGS.

1977 • 13 citations

Multiple balloon kymograph recording of the comparative action of morphine and placebos on the motility of the upper small intestine in man.

1950 • 11 citations

Use of gut cyclic motor activity to evaluate a stimulant (narcotic) and inhibitor (anticholinergic) of gastrointestinal-tract activity in the unanesthetized dog

1985 • 8 citations

Naloxone-induced facilitation of contractions, spontaneous activity and tolerance to morphine in ileum of morphine-dependent guinea-pigs.

1974 • 7 citations